CGDB Gene Information

Tag Content
CGDB ID CGD-OvA-022195
Uniprot Accession W5PL09; W5PL09; W5PL09_SHEEP
Protein Name Uncharacterized protein
Gene Name PER3
Ensembl Information ENSOART00000011292; ENSOARP000000111
Genbank Protein ID XP_012042759.1
Genbank Nucleotide ID XM_012187369.1
Organism Ovis aries
NCBI Taxa ID 9940
Circadian Information
Evidence Phase Amplitude
(FOLD)		 Sentence Tissue/Cell Data type PMID
Peak Trough External
condition
Small-scale ZT 6 ZT 18 LD 4.00 High-amplitude Bmal1, Clock, Nr1d1, Cry2 and Per3 mRNA rhythms were apparent in skeletal muscle, which were phase advanced by up to 3.5 h 2 days after phase shift, whereas Per1 expression was downregulated at this time. Pparα, Pgc1α and Nampt mRNA were constitutively expressed in both conditions. muscle Small-scale [1]
Protein Sequence
(Fasta)		 MDPCEDVERS SGKSENPRGN QRHELEGQQA SGPEAPENDA AELWSQKCEL RSKFVQTSNS 60
EQQNRNRVSD ELITVVQEMK KYFPSERHGK PNTLDALNYA LLCVHSVQAN NESFQILSQN 120
GAPQGDVTLC SLEELATIAS GHTSKTTGTF VAVFSFLSGR LVHISEQAPS ILNCQKEFLE 180
SCHFVELLAP QDMRVFYTHT AHAQLLFWNN WTQREASQYE LAPVKSFFCR IGGGEAGELQ 240
RPYCPFRITP NLIHVHSSAL MEPEPCCLLL AEKIHSGYQA PQIPADKRIF TTTHTPGCVF 300
LEIDERAVPF LGYLPQDLIG TSILAYLHPE DRPLMLAMHQ KVLKYAGHPP FEHLPIRFCC 360
QNGDYVILDS SWSSFMNPWS RKVSFIIGRH KVRTSPLNKD VFATRVKKVS NDDKDTTELQ 420
EQIQKLLLQP VHGSKSSGYG SLGSSGSQEP QVSLASSSES SGHGVDEVPE APLTLQQICA 480
SVNKIKNLGQ QLYVESRAKS ANKPVSGTRS GRPGDEQKTS SSFQTVKNNS MYTESCEDLR 540
KVQRSPSYQQ INCIDSVTRY LKSYHIPVLK RKCISSTNTT SSSSEEDRQS HRADDIQALQ 600
AISQIPTVPA SEMPTKGQST DAEGGAPWTL STVTLSLDTS QCSSSSVLVD IPPPDSELTP 660
AEHVPLACEP WTLSTHPAPL AAEAFKHSGL AKAVLSAHAQ KEEQSYVDKF QEKILSSPCS 720
FYLQQESRSK AKYLYVQGGS ASRLARSAGC RKGKHKRKKP LMWSDGRSAK DHFCPHQDGQ 780
PWCPSSASCP HASGPSLPAT VMVPSPAPCL VPALRLPATT SLGREHEALI TVLPRLPEPP 840
LPSSLQYFPA LPSAYFNTFV NLFLHDPSLS PLSSLSFSPY PFLGAAPSSE ILSSVSAVAP 900
NPGPLSSTIN PRSREEKWET RNEGHPLINS GSSSMLQLDL LQGDRPRSCA SPETVCGVRG 960
SSGTEIDGFT IKKPSIASLH SVSPPGTGPA ASGSSGSSIN FAPSDDSSEI SENGQQSQDI 1020
QKKGTFPKLA EESIWRMIKQ TPDRILMTYQ VPERVKEIVL KEDLEKLESM RRQQPQFSRG 1080
QREEIANVHS WIHSRAIPRE IDTQGCVTCG HRDSAGDAAD PTVRIQQKQQ PSDSEGPALP 1140
LQTCWTAPPP CDSLRTLAA 1159
Sequence Source Uniprot/ENA
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-AnP-057114Anas platyrhynchos47.27 0.00e+00 660.6
CGD-CaJ-041907Callithrix jacchus53.53 0.00e+00 1081.2
CGD-CaF-038549Canis familiaris59.68 0.00e+00 1232.6
CGD-CaP-050028Cavia porcellus50.82 0.00e+00 788.5
CGD-ChR-032478Chlamydomonas reinhardtii39.39 1.57e-01 35.04
CGD-ChS-042175Chlorocebus sabaeus56.01 0.00e+00 1179.5
CGD-ChH-060322Choloepus hoffmanni49.93 2.00e-164 577
CGD-DaR-072762Danio rerio38.11 0.00e+00 653.7
CGD-DaN-060659Dasypus novemcinctus66.01 0.00e+00 852.4
CGD-DiO-049550Dipodomys ordii52.88 0.00e+00 784.6
CGD-EqC-051045Equus caballus63 0.00e+00 1289.2
CGD-FeC-041831Felis catus50.71 0.00e+00 908.7
CGD-FiA-032827Ficedula albicollis53.46 0.00e+00 676
CGD-GaG-020965Gallus gallus54.22 0.00e+00 674.9
CGD-GoG-059542Gorilla gorilla52.2 0.00e+00 1068.1
CGD-HoS-062136Homo sapiens (Human)55.36 0.00e+00 1167.5
CGD-IcT-051943Ictidomys tridecemlineatus59.28 0.00e+00 1012.3
CGD-LaC-038253Latimeria chalumnae45.53 0.00e+00 657.5
CGD-LeO-053510Lepisosteus oculatus42.88 1.00e-146 518.1
CGD-LoA-064706Loxodonta africana52.98 0.00e+00 974.9
CGD-MaM-036963Macaca mulatta75.21 3.00e-157 551.6
CGD-MaE-031352Macropus eugenii57.8 2.00e-161 566.6
CGD-MeG-072597Meleagris gallopavo47.63 0.00e+00 661.8
CGD-MiM-058960Microcebus murinus55.72 0.00e+00 940.3
CGD-MoD-067747Monodelphis domestica51.53 0.00e+00 872.1
CGD-MuM-021078Mus musculus (Mouse)54.1 0.00e+00 1087.8
CGD-MuP-062621Mustela putorius furo52.68 0.00e+00 1038.5
CGD-MyL-055612Myotis lucifugus55.19 0.00e+00 887.1
CGD-NoL-069268Nomascus leucogenys56.44 0.00e+00 1174.5
CGD-OrN-041249Oreochromis niloticus46.55 4.00e-155 546.2
CGD-OrB-064112Oryza brachyantha30.36 4.51e-01 32.34
CGD-OrL-069692Oryzias latipes47.2 6.00e-166 582
CGD-OtG-043281Otolemur garnettii58.57 0.00e+00 1236.1
CGD-PaT-063745Pan troglodytes57.41 0.00e+00 1219.1
CGD-PaA-041667Papio anubis56.84 0.00e+00 1199.1
CGD-PoA-060690Pongo abelii55.95 0.00e+00 1164.4
CGD-PrC-048229Procavia capensis46.66 0.00e+00 878.2
CGD-PtV-052486Pteropus vampyrus65.99 0.00e+00 933.7
CGD-RaN-021797Rattus norvegicus54.85 0.00e+00 1096.6
CGD-SaH-047243Sarcophilus harrisii47.86 0.00e+00 921.8
CGD-SuS-028663Sus scrofa56.63 0.00e+00 1144.8
CGD-TaG-047964Taeniopygia guttata54.24 0.00e+00 674.9
CGD-TaR-032238Takifugu rubripes45.86 4.00e-160 562.8
CGD-TaS-050246Tarsius syrichta64.5 0.00e+00 857.1
CGD-TeN-064311Tetraodon nigroviridis46.29 2.00e-163 573.5
CGD-TuB-071016Tupaia belangeri55.88 0.00e+00 964.9
CGD-TuT-040951Tursiops truncatus65.86 0.00e+00 1398.6
CGD-XeT-062261Xenopus tropicalis51.74 0.00e+00 664.1
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Gene Ontology

GO:0032922--P:circadian regulation of gene expression
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045187--P:regulation of circadian sleep/wake cycle, sleep
Interpro

IPR000014--PAS
IPR013655--PAS_fold_3
IPR015524--Per_circ_prot_3
IPR022728--Period_circadian-like_C
PROSITE

PS50112--PAS
Pfam

PF08447--PAS_3
PF12114--Period_C
SMART

SM00091--PAS