CGDB Gene Information

Tag Content
CGDB ID CGD-OtG-043281
Ensembl Accession ENSOGAP00000008770.2
Protein Name PER3
Ensembl Information ENSOGAG00000009800; ENSOGAT00000009808
Organism Otolemur garnettii
NCBI Taxa ID 30611
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 15 ZT 9 LD 6 duodenum Predicted from orthologs E1C8E2
ZT 0 ZT 12 LD 5 pineal gland Predicted from orthologs E1C8E2
ZT 8 ZT 0 LD 4.6 brown adipose tissue Predicted from orthologs O70361
ZT 8 ZT 0 LD 2.46 epididymal white adipose tissue Predicted from orthologs O70361
ZT 12 ZT 0 LD 10 femur vertebra Predicted from orthologs O70361
ZT 8 ZT 4 LD 5.2 heart Predicted from orthologs O70361
ZT 12 ZT 0 LD 35 jejunum Predicted from orthologs O70361
CT 9 CT 21 DD1 2 SCN Predicted from orthologs O70361
ZT 8 ZT 16 LD 2.5 SCN Predicted from orthologs O70361
CT 15 CT 3 DD1 2 testis Predicted from orthologs O70361
CT 15 CT 3 DD1 4 liver Predicted from orthologs O70361
ZT 8 ZT 0 LD 14 lumbar vertebra Predicted from orthologs O70361
CT 0 CT 12 DD2 8.8 NIH-3T3 cells Predicted from orthologs O70361
ZT 8 ZT 0 LD 23 liver Predicted from orthologs O70361
ZT 6 ZT 18 LD 4 muscle Predicted from orthologs W5PL09
ZT 12 ZT 0 LD 25 abdominal adipose tissue Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 2.3 basolateral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 12 ZT 0 LD 5 entral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 4.5 hippocampus Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 14 nucleus accumbens core Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 5 nucleus accumbens shell Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 8 prefrontal cortex Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 6 SCN Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 2 ventral tegmental area Predicted from orthologs Q8CJE2
Descriptionperiod circadian clock 3 [Source:HGNC Symbol;Acc:HGNC:8847](View all)
Protein Sequence
(Fasta)		 MDPCEDLEMP GGQTPDPGRL EAGGEAERWS PQFQLQRKFV ESSNREQQDR NRVSEELVMV 60
VQEMKKYFPS ERHNKPSTLD ALNYALRCVH SVQANSGFFQ TLSQNGASQA DVTTYSLEEL 120
ATIASEHTSK NTDTFVAVFS FLSGRLVHIS EQAALTLNCK KGCLESSHFV DLLAPQDVRV 180
FYTHTARAQL PFWNNWTQRA ASQCEPALVK SFFCRIRGGE DRRKQEKYYY PFRIIPYMIH 240
VRSSAQPESE PCCLTLVEKI HSGYEAPRIP VDKRIFTTTH SPGCVFLEVD ERAVPLLGYL 300
PQDLIGTSIL TYLHPEDRSL MIAVHQKVLK YAGHPPFEHS PIRFCTQNGD YIILDSSWSS 360
FVNPWSRKVS FIIGRHKVQT SPLNEDVFAT RIKKMNNNDK DITELQEQIH KLLLQPVHVS 420
ASSGYGSLGS SGSQEQHVSA ASSSESSGHC AEEPRKEPMT LQQVYASVNK IKNLGQQLYI 480
ESMTRSSVKP VTGTCTEPLS ADEQKAFSSF QTLRNNSLCT ESCEDLRKGQ HSPSYQQINC 540
IDSVIRYLKS YNIPALKRKY VSCANTTSSS SEDDKQNLKA DDVQALHAIP KSEMPANEWS 600
TDAEVGAPRT LSTAALSLGS GISQCSYSST MVHVPPTEAA EDATLACEPW TLNTQPVPLT 660
SDEFKPIGLT KAVLSAHTQK EEQNYVDKFR ERILSSPYSS YLQQESRNEA KYSFVPGDST 720
SKQTRSAGCK KGKHKRKKVP APSASSSSDA GSRPHTRGTL GRTQPQYPPA ASCPHALGLS 780
FPSSVMIPSQ APYLTPAFPL PPVTSLGRGD AAVGTALDHL PEPPSASGLQ PLPAFPPPYL 840
DTVMTIFLHS PPVCPLLSSS FFPYPFLGAT DSSEIPPPTA AVAPYPEPSP SVTIQTGVEE 900
QWETGGEGHP FISSRSSSPL QLNLLQEEMP KSSEFSDHMK RDICPKPEYQ CVTGKSENKN 960
SRPPASELSP LSPHKESQSG ARFLIGSSDS STYFASSDYS SGISPNGQQS QDTQKKEAFP 1020
SSAEEPIWRM IREVPESILM TYQVPERVKE VVLKEDLEKL ERMRQQQPRF SHGQKEELAK 1080
IYSWVQSQTV PQEADIQDCA TGENKGSIDA AAESCGQDPA EDSS 1124
Nucleotide Sequence
(Fasta)		 ATGGACCCCT GCGAAGATCT GGAGATGCCC GGCGGGCAGA CTCCTGACCC CGGGCGACTG 60
GAGGCCGGTG GAGAGGCGGA GAGGTGGAGT CCTCAGTTCC AGCTGCAGAG GAAATTCGTG 120
GAAAGCAGCA ACAGGGAACA GCAAGATCGA AACAGAGTTT CTGAAGAACT TGTAATGGTT 180
GTCCAAGAAA TGAAGAAATA TTTCCCATCA GAGAGACACA ATAAGCCAAG TACTCTAGAT 240
GCCCTCAATT ATGCCCTTCG CTGCGTGCAC AGTGTGCAAG CAAACAGTGG GTTTTTCCAG 300
ACTCTCAGTC AAAATGGAGC ATCTCAGGCA GATGTGACCA CATACAGTCT TGAGGAGCTG 360
GCCACTATTG CTTCAGAACA CACTTCTAAA AACACAGATA CCTTTGTGGC AGTGTTTTCA 420
TTTCTGTCTG GAAGGTTAGT GCACATTTCT GAACAGGCTG CTTTGACCCT GAATTGTAAG 480
AAAGGTTGCT TGGAGTCTTC TCACTTTGTT GACCTGCTCG CTCCTCAAGA CGTGAGAGTG 540
TTCTACACGC ACACTGCCCG AGCTCAGCTT CCCTTTTGGA ACAACTGGAC CCAAAGAGCA 600
GCGTCCCAGT GTGAACCCGC TCTCGTGAAG TCCTTCTTCT GCAGGATCCG TGGAGGTGAA 660
GACCGGAGAA AGCAAGAGAA GTATTACTAC CCATTCCGGA TCATTCCCTA CATGATCCAT 720
GTACGAAGTT CTGCCCAACC AGAATCGGAA CCCTGCTGTC TCACACTGGT TGAAAAGATT 780
CACTCTGGTT ACGAAGCTCC TAGAATCCCA GTGGATAAAA GAATTTTTAC CACAACACAC 840
AGCCCAGGGT GTGTTTTTCT TGAAGTGGAT GAAAGAGCAG TGCCTTTGCT GGGTTACCTA 900
CCTCAGGACC TGATCGGGAC CTCCATCCTA ACATACTTGC ACCCAGAAGA TCGTTCTCTG 960
ATGATTGCTG TACACCAGAA AGTCTTGAAG TATGCAGGCC ATCCTCCCTT TGAACATTCT 1020
CCCATTAGAT TTTGTACTCA AAATGGAGAT TACATCATAT TGGATTCCAG TTGGTCCAGC 1080
TTTGTGAACC CATGGAGCCG GAAGGTTTCT TTCATCATTG GTCGGCATAA AGTTCAAACG 1140
AGTCCACTAA ATGAGGATGT TTTTGCTACC AGAATAAAAA AGATGAACAA TAATGACAAA 1200
GACATAACAG AATTACAAGA ACAAATTCAC AAACTTCTCT TGCAGCCAGT CCACGTGAGC 1260
GCTTCCAGTG GCTACGGGAG CCTGGGCAGC AGCGGCTCCC AGGAGCAGCA CGTGAGCGCA 1320
GCATCTTCCA GCGAGTCCAG TGGGCACTGT GCGGAGGAGC CGCGGAAGGA GCCGATGACG 1380
TTGCAACAGG TCTATGCCAG TGTAAACAAA ATTAAGAATC TGGGCCAGCA GCTATACATT 1440
GAGTCAATGA CCAGATCATC AGTCAAGCCA GTGACGGGGA CATGCACAGA GCCGCTCAGT 1500
GCTGATGAGC AGAAGGCCTT TTCTTCCTTC CAGACATTGA GAAATAATAG CTTGTGTACT 1560
GAGTCTTGTG AGGATTTGAG GAAAGGTCAG CACAGCCCAT CCTATCAACA AATAAACTGT 1620
ATTGACAGTG TTATCAGATA CCTGAAGAGC TATAATATTC CAGCTTTAAA AAGAAAGTAC 1680
GTATCCTGTG CAAATACAAC TTCTTCATCC TCTGAAGACG ACAAACAGAA CCTCAAGGCG 1740
GATGATGTCC AAGCATTGCA CGCCATACCT AAGTCAGAAA TGCCAGCAAA TGAATGGTCC 1800
ACAGATGCTG AAGTAGGAGC CCCACGTACC TTGTCCACTG CAGCGCTGAG CTTGGGGTCA 1860
GGCATAAGCC AGTGCAGTTA CAGCAGCACC ATGGTTCACG TCCCGCCCAC AGAGGCAGCA 1920
GAAGATGCTA CCCTGGCATG TGAGCCCTGG ACTCTCAACA CACAGCCAGT CCCTTTGACC 1980
TCGGATGAGT TCAAGCCCAT AGGGCTCACG AAGGCTGTAC TGTCAGCCCA CACACAGAAG 2040
GAGGAACAGA ATTACGTTGA TAAATTCCGG GAGAGGATCC TGTCATCACC CTATAGCTCC 2100
TATCTTCAGC AGGAAAGCAG AAACGAAGCT AAATATTCTT TTGTTCCAGG AGATTCTACT 2160
TCTAAACAGA CAAGATCAGC TGGTTGCAAG AAGGGGAAGC ATAAACGCAA GAAGGTGCCG 2220
GCACCCTCGG CCAGCAGCAG CTCTGATGCC GGCTCCAGAC CCCACACCAG GGGAACTCTT 2280
GGCCGCACAC AGCCCCAGTA CCCTCCTGCT GCCTCCTGTC CTCACGCCTT GGGCCTGTCA 2340
TTCCCGTCTT CTGTGATGAT TCCCAGCCAG GCCCCTTACC TCACCCCAGC TTTCCCCCTC 2400
CCACCCGTGA CCTCTCTAGG AAGAGGAGAT GCAGCTGTGG GCACTGCACT AGACCATCTG 2460
CCTGAGCCGC CCTCGGCCAG TGGCCTGCAG CCTCTCCCAG CTTTCCCCCC TCCTTATTTG 2520
GATACTGTCA TGACCATTTT CCTGCATAGC CCCCCAGTCT GTCCTCTCTT GTCATCATCA 2580
TTCTTTCCGT ATCCATTCTT GGGAGCAACA GATTCTTCTG AAATACCACC CCCAACAGCA 2640
GCAGTGGCTC CATACCCAGA ACCATCACCT TCAGTCACCA TCCAGACGGG AGTTGAGGAG 2700
CAATGGGAGA CTGGTGGTGA AGGGCACCCG TTTATTAGTT CAAGGAGCAG CTCACCACTG 2760
CAGCTGAACT TACTTCAGGA GGAAATGCCC AAATCTTCTG AATTTTCAGA TCACATGAAA 2820
AGGGATATTT GCCCAAAACC TGAGTATCAG TGTGTTACGG GCAAGAGTGA GAATAAGAAC 2880
AGTCGTCCTC CTGCCAGTGA ACTGTCCCCA CTGTCGCCTC ACAAGGAGTC TCAGTCTGGA 2940
GCAAGATTTT TAATAGGAAG CAGTGACAGC AGTACTTATT TTGCTAGTAG TGATTATTCT 3000
TCTGGAATAT CCCCAAATGG GCAGCAATCT CAGGATACAC AGAAAAAGGA AGCATTTCCC 3060
AGTTCAGCTG AAGAGCCCAT CTGGAGAATG ATACGAGAAG TCCCGGAGAG CATTCTCATG 3120
ACGTATCAGG TACCTGAGAG GGTTAAAGAA GTTGTACTAA AAGAAGACCT AGAAAAGCTG 3180
GAAAGAATGA GGCAGCAGCA GCCCCGGTTT TCTCATGGCC AAAAGGAGGA GCTTGCCAAG 3240
ATCTATTCTT GGGTTCAGAG CCAGACTGTC CCTCAAGAAG CAGACATCCA AGACTGTGCC 3300
ACTGGTGAAA ACAAAGGTTC AATTGATGCT GCTGCAGAAT CCTGTGGTCA GGACCCAGCA 3360
GAAGACAGCA GTTGA 3375
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-GaG-020965Gallus gallus46.11 0.00e+00 835.1
CGD-MuM-021078Mus musculus (Mouse)60.11 0.00e+00 1263.8
CGD-OvA-022195Ovis aries58.57 0.00e+00 1236.1
CGD-RaN-021797Rattus norvegicus60.19 0.00e+00 1275
Gene Ontology

GO:0005515--protein binding
GO:0032922--circadian regulation of gene expression
GO:0045187--regulation of circadian sleep/wake cycle, sleep
GO:0007623--circadian rhythm
GO:0019900--kinase binding
GO:0031625--ubiquitin protein ligase binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0006355--regulation of transcription, DNA-templated
GO:0004871--signal transducer activity
GO:0007165--signal transduction