CGDB Gene Information

Tag Content
CGDB ID CGD-MyL-055612
Ensembl Accession ENSMLUP00000014533.2
Protein Name PER3
Ensembl Information ENSMLUG00000015940; ENSMLUT00000015954
Organism Myotis lucifugus
NCBI Taxa ID 59463
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
ZT 15 ZT 9 LD 6 duodenum Predicted from orthologs E1C8E2
ZT 0 ZT 12 LD 5 pineal gland Predicted from orthologs E1C8E2
ZT 15 ZT 3 LD 2 blood Predicted from orthologs P56645
CT 16 CT 4 DD2 2.7 human HaCaT keratinocytes Predicted from orthologs P56645
ZT 4 ZT 21 LD 3.5 human HaCaT keratinocytes Predicted from orthologs P56645
ZT 8 ZT 0 LD 4.6 brown adipose tissue Predicted from orthologs O70361
ZT 8 ZT 0 LD 2.46 epididymal white adipose tissue Predicted from orthologs O70361
ZT 12 ZT 0 LD 10 femur vertebra Predicted from orthologs O70361
ZT 8 ZT 4 LD 5.2 heart Predicted from orthologs O70361
ZT 12 ZT 0 LD 35 jejunum Predicted from orthologs O70361
CT 9 CT 21 DD1 2 SCN Predicted from orthologs O70361
ZT 8 ZT 16 LD 2.5 SCN Predicted from orthologs O70361
CT 15 CT 3 DD1 2 testis Predicted from orthologs O70361
CT 15 CT 3 DD1 4 liver Predicted from orthologs O70361
ZT 8 ZT 0 LD 14 lumbar vertebra Predicted from orthologs O70361
CT 0 CT 12 DD2 8.8 NIH-3T3 cells Predicted from orthologs O70361
ZT 8 ZT 0 LD 23 liver Predicted from orthologs O70361
ZT 6 ZT 18 LD 4 muscle Predicted from orthologs W5PL09
ZT 12 ZT 0 LD 25 abdominal adipose tissue Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 2.3 basolateral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 12 ZT 0 LD 5 entral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 4.5 hippocampus Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 14 nucleus accumbens core Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 5 nucleus accumbens shell Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 8 prefrontal cortex Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 6 SCN Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 2 ventral tegmental area Predicted from orthologs Q8CJE2
Descriptionperiod circadian clock 3 [Source:HGNC Symbol;Acc:HGNC:8847](View all)
Protein Sequence
(Fasta)		 SYSERQDRNR VSEELITVVQ EKKYFPSGRH HKPSTLDALN YARCVHSVQA SSEFFQILSP 60
NGAPQADVTM YSLEELASMA AEHTSKNTDT FVAVFSLVSG RVVHISEQAP SILSCRRESL 120
ASSHFAELLA PQDVRVFYTH TAHAQLPVWS SWTQRASQYE LAPVKSFFCR IREGGSRGQR 180
YAPFRVIPYL IHVRPQSEPE PEPCCLALAE KMHSGYEAPR IPVDKRIFTT THTPGCVFLE 240
IDDRAVPLLG YLPQDLVGTS ILAHLHPEDR ALMVAVHQEV LRSAGRAPSE HRAVRFCTHN 300
GDYVILDSSW SGFVDPWSRK VSFIMGRHKV RTSPLNEDVF AARISKMDNN DKDITELQEQ 360
IHKLLLQPVH GSTSSGYSSL GSSGSQEQHV SVASSGESSG PGAEDAQKEP LTLQQVYASV 420
NKIKTLGQQL YIESMTKPPN KPAVGTRTGR PSGEQEAFSP VRPWKNESVR TESCQGLRKD 480
QHRPSYQQIN CIDGVIRYLR SCRTPALKRK CISCTNTASS SEDDRQAHKA DDAHAVREVP 540
ARGRSTGAEG GASRTEARAA PSLGSGISQC SYSSTMVHAP PPEPAEPTPA EDAAPACEPW 600
APGTLPAPLT AEEFQHVGLT TAVLSAHTQR EEQDYVDRFR EKMLSSPYSS YLQHEGRGQA 660
TCSDGQGASS PGQARSPGGK KGKHKRKKLP EPLGSRCAED ACCPHFGRDV QDAQPWSLPP 720
ASPLHAPGLA FPAAVVAPGQ ALPYLMPALP LPTVAPGGHC PPFPDVPSPY AETFLTIVLP 780
GPSVCPLWAP SFSPYLYLGA AGPSETPPSV PTAAPSVEPP FPVTTQRGAG QSWEMQSAGC 840
PGPSSRGSSP LQLALLQEDR PPSCESAEQV R 871
Nucleotide Sequence
(Fasta)		 TCTTACAGCG AACGGCAAGA CCGGAACAGA GTTTCTGAAG AACTGATCAC GGTTGTCCAA 60
GAAAAAAAAT ACTTCCCGTC GGGGAGACAC CATAAACCGA GCACCCTGGA TGCCCTCAAC 120
TATGCCCGCT GTGTGCACAG CGTACAAGCA AGCAGTGAGT TTTTCCAGAT TCTCAGTCCC 180
AATGGAGCGC CTCAAGCAGA TGTGACCATG TACAGTCTTG AGGAGCTGGC CTCCATGGCT 240
GCAGAGCACA CTTCCAAGAA CACAGACACC TTCGTGGCCG TGTTCTCATT GGTGTCTGGG 300
AGGGTGGTGC ACATCTCCGA GCAGGCGCCT TCCATCCTGA GCTGTCGGAG AGAGTCCTTG 360
GCGTCCTCTC ACTTCGCGGA GCTGCTTGCC CCTCAAGATG TGAGGGTGTT CTACACGCAC 420
ACGGCCCACG CTCAGCTTCC CGTCTGGAGC AGCTGGACCC AAAGAGCGTC GCAGTACGAA 480
CTGGCTCCCG TGAAGTCCTT TTTCTGCAGG ATCCGCGAAG GCGGCAGCCG AGGGCAGCGT 540
TACGCCCCGT TCCGGGTGAT TCCCTATTTG ATTCACGTGC GGCCGCAGTC GGAGCCGGAG 600
CCGGAGCCCT GCTGCCTTGC GCTGGCCGAG AAGATGCACT CTGGCTACGA AGCTCCTCGG 660
ATCCCCGTGG ATAAAAGAAT TTTCACCACA ACACACACTC CAGGCTGTGT TTTTCTTGAA 720
ATAGATGACC GGGCCGTGCC TTTGCTGGGG TACCTGCCGC AGGACCTGGT CGGCACGTCC 780
ATCCTCGCGC ACCTGCACCC GGAAGACCGC GCTCTGATGG TCGCCGTCCA CCAGGAAGTG 840
CTGCGGTCCG CAGGCCGCGC CCCCTCTGAG CACCGCGCCG TTCGCTTCTG CACACACAAC 900
GGCGACTACG TCATCCTGGA TTCCAGCTGG TCCGGCTTCG TGGACCCGTG GAGCCGGAAG 960
GTGTCCTTCA TCATGGGCCG GCACAAAGTG CGGACGAGTC CGCTGAACGA GGATGTTTTT 1020
GCTGCCAGAA TAAGCAAGAT GGACAATAAC GACAAAGACA TAACGGAATT ACAGGAACAG 1080
ATTCACAAAC TTCTGTTACA GCCAGTCCAC GGGAGCACCT CTAGTGGCTA CAGCAGCCTG 1140
GGGAGCAGCG GGTCCCAGGA GCAGCACGTC AGCGTGGCCT CCTCCGGCGA GTCCAGCGGG 1200
CCGGGGGCGG AGGACGCCCA GAAGGAGCCG TTGACTTTGC AGCAGGTCTA TGCCAGTGTA 1260
AATAAAATTA AAACCCTGGG GCAGCAGCTG TACATCGAGT CCATGACCAA ACCCCCCAAC 1320
AAGCCAGCGG TGGGGACGCG CACAGGACGG CCCAGTGGTG AGCAGGAGGC CTTTTCTCCC 1380
GTACGGCCCT GGAAGAATGA GAGCGTGCGC ACTGAGTCTT GCCAGGGTTT GAGGAAAGAC 1440
CAGCATCGCC CCTCCTACCA GCAAATCAAC TGCATCGACG GTGTCATCAG ATACCTGAGG 1500
AGCTGCCGCA CCCCAGCTCT GAAGAGAAAG TGTATCTCCT GCACAAATAC CGCTTCGTCC 1560
TCGGAAGACG ACCGGCAGGC CCACAAGGCA GACGATGCCC ACGCCGTGCG AGAAGTGCCA 1620
GCTCGCGGAC GGTCCACCGG TGCCGAGGGC GGAGCTTCGC GGACCGAGGC CAGGGCGGCG 1680
CCGAGCCTGG GCTCCGGCAT CAGCCAGTGC AGCTACAGCA GCACCATGGT CCACGCGCCG 1740
CCCCCAGAGC CAGCAGAACC GACTCCCGCT GAGGACGCCG CCCCCGCCTG CGAGCCCTGG 1800
GCGCCCGGCA CCCTGCCGGC CCCGTTGACT GCGGAGGAGT TTCAGCACGT GGGGCTCACC 1860
ACGGCCGTGC TGTCGGCGCA CACGCAGAGG GAGGAGCAGG ACTACGTGGA CAGGTTCCGG 1920
GAGAAGATGC TGTCCTCCCC CTACAGCTCC TACCTGCAGC ACGAAGGCAG AGGGCAGGCC 1980
ACGTGTTCAG ATGGTCAAGG AGCCTCCTCT CCCGGGCAGG CCAGGTCTCC TGGGGGCAAG 2040
AAGGGGAAGC ACAAGCGGAA GAAGCTGCCG GAGCCGCTGG GCAGCCGGTG TGCGGAGGAC 2100
GCCTGCTGTC CCCACTTCGG AAGGGACGTC CAGGACGCTC AGCCCTGGAG CCTGCCCCCT 2160
GCCTCCCCTC TCCACGCCCC CGGCCTGGCG TTCCCGGCGG CGGTGGTGGC TCCCGGCCAG 2220
GCCCTCCCTT ACCTCATGCC AGCGTTGCCC CTGCCCACCG TGGCCCCGGG GGGGCACTGC 2280
CCGCCTTTCC CAGATGTGCC TTCACCTTAC GCGGAGACTT TCCTAACCAT TGTGCTGCCT 2340
GGCCCCTCTG TGTGCCCTCT GTGGGCACCG TCGTTCTCTC CATACCTGTA TTTGGGAGCA 2400
GCAGGCCCTT CTGAAACGCC ACCCTCAGTA CCAACAGCAG CTCCCAGTGT GGAACCACCA 2460
TTTCCAGTCA CCACCCAGAG GGGCGCTGGG CAGAGCTGGG AGATGCAGAG CGCAGGGTGC 2520
CCGGGCCCCA GCTCCAGGGG CAGCTCGCCG CTGCAGCTGG CCTTGCTGCA GGAGGACAGG 2580
CCCCCGTCCT GCGAGTCTGC AGAGCAGGTG AGA 2613
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans23.24 3.30e-16 84.34
CGD-GaG-020965Gallus gallus42.9 1.00e-179 626.7
CGD-HoS-021431Homo sapiens (Human)57.41 0.00e+00 960.3
CGD-MuM-021078Mus musculus (Mouse)55.05 0.00e+00 897.1
CGD-OvA-022195Ovis aries55.19 0.00e+00 887.1
CGD-RaN-021797Rattus norvegicus54.93 0.00e+00 900.6
Gene Ontology

GO:0005515--protein binding
GO:0032922--circadian regulation of gene expression
GO:0045187--regulation of circadian sleep/wake cycle, sleep
GO:0007623--circadian rhythm
GO:0019900--kinase binding
GO:0031625--ubiquitin protein ligase binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter