CGDB Gene Information

Tag Content
CGDB ID CGD-PaT-063745
Ensembl Accession ENSPTRP00000043002.5
Protein Name PER3
Ensembl Information ENSPTRG00000000099; ENSPTRT00000046803
Organism Pan troglodytes
NCBI Taxa ID 9598
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
ZT 15 ZT 9 LD 6 duodenum Predicted from orthologs E1C8E2
ZT 0 ZT 12 LD 5 pineal gland Predicted from orthologs E1C8E2
ZT 15 ZT 3 LD 2 blood Predicted from orthologs P56645
CT 16 CT 4 DD2 2.7 human HaCaT keratinocytes Predicted from orthologs P56645
ZT 4 ZT 21 LD 3.5 human HaCaT keratinocytes Predicted from orthologs P56645
ZT 8 ZT 0 LD 4.6 brown adipose tissue Predicted from orthologs O70361
ZT 8 ZT 0 LD 2.46 epididymal white adipose tissue Predicted from orthologs O70361
ZT 12 ZT 0 LD 10 femur vertebra Predicted from orthologs O70361
ZT 8 ZT 4 LD 5.2 heart Predicted from orthologs O70361
ZT 12 ZT 0 LD 35 jejunum Predicted from orthologs O70361
CT 9 CT 21 DD1 2 SCN Predicted from orthologs O70361
ZT 8 ZT 16 LD 2.5 SCN Predicted from orthologs O70361
CT 15 CT 3 DD1 2 testis Predicted from orthologs O70361
CT 15 CT 3 DD1 4 liver Predicted from orthologs O70361
ZT 8 ZT 0 LD 14 lumbar vertebra Predicted from orthologs O70361
CT 0 CT 12 DD2 8.8 NIH-3T3 cells Predicted from orthologs O70361
ZT 8 ZT 0 LD 23 liver Predicted from orthologs O70361
ZT 6 ZT 18 LD 4 muscle Predicted from orthologs W5PL09
ZT 12 ZT 0 LD 25 abdominal adipose tissue Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 2.3 basolateral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 12 ZT 0 LD 5 entral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 4.5 hippocampus Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 14 nucleus accumbens core Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 5 nucleus accumbens shell Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 8 prefrontal cortex Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 6 SCN Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 2 ventral tegmental area Predicted from orthologs Q8CJE2
Descriptionperiod circadian clock 3 [Source:VGNC Symbol;Acc:VGNC:6130](View all)
Protein Sequence
(Fasta)		 MPRGEAPGPG RRGAEDEALG EESGERWSPE FHLQRKLADS SHSEQQDRNR VSEELIMVVQ 60
EMKKYFPSER RNKPSTLDAL NYALRCVHSV QANSEFFQIL SQNGAPQADV SMYSLEELAA 120
IASEHTSKNT DTFVAVFSFL SGRLVHISEQ AALILNRKKD VLASSHFVDL LAPQDVRVFY 180
AHTARAQLPF WNNWTQRAAR YECAPVKPFF CRIRGGEDRK QEKCHSPFRI IPYLIHVRHP 240
AQPESESEPC CLTVVEKIHS GYEAPRIPVN KRIFTTTHTP GCVFLEVDEK AVPLLGYLPQ 300
DLIGTSILSY LHPEDRSLMV AIHQKVLKYA GHPPFEHSPI RFCTQNGDYI ILDSSWSSFV 360
NPWSRKVSFI IGRHKVRTSP LNEDVFATKI KKMNNNDKDI TELQEQIYKL LLQPVHVSVS 420
SGYGSLGSSG SQEQLVSIAS SSEASGHCVE ETKAEQMTLQ QVYASVNKIK NLGQQLYIES 480
MTKSSFKPVT GTRTEPNGGG ECKAFTSFHQ TLKNNSVYTE PCEDLRNDEH SPSYQQINCI 540
DSVIRYLKSY NIPALKRKCI SCTNTTSSSS EEDKQNHKAD DVQALQAGLQ IPAIPKSEVP 600
TNGRSIDTGG GAPQILSTAM LSLGSGISQC GYSSTIVHVP PPETARDATL FCEPWTLNMQ 660
PAPLTSEEFK HVGLTAAVLS AHTQKEEQNY VDKFREKILS SPYSSYLQQE SRSKAKYSYF 720
QGDSTSKQTR SAGCRKGKHK RKKLPEPPDS SSSNTGSGPR RGAHQNAQPC CPSAASSPHT 780
SSLTFPPAAM VPSQAPYLVP AFPLPAATSP GREYAAPGTA PEGLHGPPLS EGLQPYPAFP 840
FPYLDTFMTV FLPDPPVCPL LSPSFFPCPF LGATASSAIS PSMLSAMSPT LDPTPSVTSQ 900
RREEEKWEAQ SEGHPFITSR SSSPLQLNLL QEEMPRPSES PDQMRRNTCP QAEYCVTGNN 960
GSESSPATTG ALSTGSPPRE NPSHPTASAL STGSPPMENP SHPTASTLSM GLPPSGTPSH 1020
PTATVLSTGS PPSKSPSRTG SAASGSSDSS IYLTSSVYSS KISQNGQQSQ DVQKKETFPN 1080
VAEEPIWRMI RQTPERILMT YQVPERVKEV VLKEDLEKLE SMRQQQPQFS HGQKEELAKV 1140
YNWIQSQTVT QEIDIQACVT CGNEDSADGA ATSCGQVLVE DSS 1183
Nucleotide Sequence
(Fasta)		 TGCGCGGCCG GGCGGGAGTT CTGGGCACTC GCACGCGGCA GAGGAGCCCC GCGAGCCCTG 60
TCCTCGGCCG GAGTCCTGAA AGTCGAGCGA GCTCCGGGTT TTGAAAATGC TGGAGGGAAA 120
AGCTCCTCGG AGATGAGCGT GACCCCCTGG CTCGTGGTGG CCGCCTGTTG TCACTAACGC 180
CATGGCGGGG ACCGGAGTGA GAAACCGGTG TCTGTCACTG ACTGCAAAGT GAGCGAGAAG 240
CAGGCTACGG GCCGTCCCAG CACGACGTGG AGCCCCGCGG AGACCTGGAG ATGCCCCGCG 300
GGGAAGCTCC TGGCCCCGGG AGACGGGGGG CTGAGGACGA GGCCCTGGGC GAAGAATCGG 360
GGGAGCGGTG GAGCCCCGAG TTCCATCTGC AGAGGAAATT GGCGGACAGC AGCCACAGTG 420
AACAGCAAGA TCGAAACAGA GTTTCTGAAG AACTTATCAT GGTTGTCCAA GAAATGAAAA 480
AATACTTCCC CTCAGAGAGA CGCAATAAAC CAAGCACTCT AGATGCCCTC AACTATGCCC 540
TCCGCTGTGT CCACAGCGTG CAAGCAAACA GTGAGTTTTT CCAGATTCTC AGTCAGAATG 600
GAGCACCTCA GGCAGATGTG AGCATGTACA GTCTTGAGGA GCTGGCCGCT ATTGCTTCAG 660
AACACACTTC CAAAAACACA GATACCTTTG TGGCAGTATT TTCATTTCTG TCTGGAAGGT 720
TAGTGCACAT TTCTGAACAG GCTGCTTTGA TCCTGAATCG TAAGAAAGAT GTCCTGGCGT 780
CTTCTCACTT TGTTGACCTG CTTGCACCTC AAGACGTGAG GGTATTCTAC GCGCACACTG 840
CCAGAGCTCA GCTTCCTTTC TGGAACAACT GGACCCAAAG AGCTGCACGG TATGAATGTG 900
CTCCGGTGAA ACCTTTTTTC TGCAGGATCC GTGGAGGTGA AGACAGAAAG CAAGAGAAGT 960
GTCACTCCCC ATTCCGGATC ATCCCCTATC TGATTCATGT ACGTCACCCT GCCCAGCCAG 1020
AATCGGAATC GGAACCTTGC TGTCTCACTG TGGTTGAAAA GATTCACTCT GGTTATGAAG 1080
CTCCTCGGAT CCCAGTGAAT AAAAGAATCT TCACCACCAC ACACACCCCA GGGTGTGTTT 1140
TTCTTGAAGT AGATGAAAAA GCAGTGCCTT TGCTGGGTTA CCTACCTCAG GACCTGATTG 1200
GAACATCGAT CCTAAGCTAC CTGCACCCTG AAGATCGTTC TCTGATGGTT GCCATACACC 1260
AAAAAGTTTT GAAGTATGCA GGGCATCCTC CCTTTGAACA TTCTCCCATT CGATTTTGTA 1320
CTCAAAACGG AGACTACATC ATACTGGATT CCAGTTGGTC CAGCTTTGTG AATCCCTGGA 1380
GCCGGAAGGT TTCTTTCATC ATTGGTCGGC ATAAAGTTCG AACGAGCCCA CTAAATGAGG 1440
ATGTTTTTGC TACCAAAATT AAAAAGATGA ACAATAATGA CAAAGACATA ACAGAATTAC 1500
AAGAACAAAT TTACAAACTT CTCTTACAGC CAGTTCACGT GAGCGTGTCC AGCGGCTACG 1560
GGAGCCTGGG GAGCAGCGGG TCGCAGGAGC AGCTTGTCAG CATCGCCTCC TCCAGTGAGG 1620
CCAGCGGGCA CTGCGTGGAG GAGACGAAGG CGGAGCAGAT GACCTTGCAG CAGGTCTATG 1680
CCAGTGTGAA CAAAATTAAG AATCTGGGTC AGCAGCTCTA CATTGAGTCA ATGACCAAAT 1740
CATCCTTCAA GCCAGTGACG GGGACACGCA CAGAACCGAA TGGTGGTGGT GAATGTAAGG 1800
CCTTTACTTC CTTCCACCAA ACACTGAAAA ATAATAGTGT GTACACTGAG CCCTGTGAGG 1860
ATTTGAGGAA CGATGAGCAC AGCCCATCCT ATCAACAGAT CAACTGTATC GACAGTGTCA 1920
TCAGGTACCT GAAGAGCTAC AACATTCCAG CTTTGAAAAG AAAGTGTATC TCCTGTACAA 1980
ATACAACTTC TTCCTCCTCA GAAGAAGACA AACAGAACCA CAAGGCAGAT GATGTCCAAG 2040
CCTTACAAGC TGGTTTGCAA ATCCCAGCCA TACCTAAATC AGAAGTGCCA ACAAATGGAC 2100
GGTCCATAGA CACAGGAGGA GGAGCTCCAC AGATCCTGTC CACGGCGATG CTGAGCTTGG 2160
GGTCGGGCAT AAGCCAATGC GGTTACAGCA GCACCATTGT CCATGTCCCA CCCCCAGAGA 2220
CAGCCAGGGA TGCCACCCTC TTCTGTGAGC CCTGGACCCT GAACATGCAG CCAGCCCCTT 2280
TGACCTCGGA AGAATTTAAA CACGTGGGGC TCACAGCGGC TGTTCTGTCA GCGCACACCC 2340
AGAAGGAAGA GCAGAATTAT GTTGATAAAT TCCGAGAAAA GATCCTGTCA TCACCCTACA 2400
GCTCCTATCT TCAGCAAGAA AGCAGGAGCA AAGCTAAATA TTCATATTTT CAAGGAGATT 2460
CTACTTCCAA GCAGACGCGG TCGGCCGGCT GCAGGAAAGG GAAGCACAAG CGGAAGAAGC 2520
TGCCGGAGCC GCCAGACAGC AGCAGCTCGA ACACCGGCTC TGGTCCCCGC AGGGGAGCGC 2580
ATCAGAACGC ACAGCCCTGC TGCCCCTCCG CGGCCTCCTC TCCGCACACC TCCAGCCTGA 2640
CCTTCCCACC TGCCGCCATG GTGCCCAGCC AGGCCCCTTA CCTCGTCCCA GCTTTTCCCC 2700
TCCCAGCCGC GACCTCTCCC GGAAGAGAAT ACGCAGCCCC CGGAACTGCA CCTGAAGGCC 2760
TGCATGGGCC GCCCTTGTCC GAGGGCTTGC AGCCTTACCC AGCTTTCCCT TTTCCTTACT 2820
TGGATACTTT TATGACCGTT TTCCTGCCTG ACCCCCCTGT CTGTCCTCTG TTGTCGCCAT 2880
CGTTCTTTCC ATGTCCATTC CTGGGGGCGA CAGCCTCTTC TGCGATATCA CCCTCAATGT 2940
TGTCAGCAAT GAGTCCAACC CTGGACCCAA CCCCTTCAGT CACCAGCCAA AGGAGAGAGG 3000
AGGAAAAGTG GGAGGCACAA AGCGAGGGGC ACCCGTTCAT TACTTCGAGA AGCAGCTCAC 3060
CCTTGCAGTT AAACTTACTT CAGGAAGAGA TGCCCAGACC CTCTGAATCT CCAGATCAGA 3120
TGAGAAGGAA CACGTGCCCA CAAGCTGAGT ATTGTGTTAC AGGCAACAAT GGCAGTGAGA 3180
GCAGTCCTGC TACTACCGGT GCACTGTCCA CGGGGTCACC TCCCAGGGAG AATCCATCCC 3240
ATCCTACTGC CAGCGCTCTG TCCACAGGAT CACCTCCCAT GGAGAATCCA TCCCATCCTA 3300
CTGCCAGCAC ACTGTCCATG GGATTGCCTC CCAGCGGGAC TCCATCCCAT CCTACTGCCA 3360
CTGTTCTGTC CACGGGGTCA CCTCCCAGCA AATCTCCATC CAGAACTGGT TCAGCAGCAT 3420
CAGGAAGCAG CGACAGCAGT ATATACCTTA CTAGTAGTGT TTATTCTTCT AAAATCTCCC 3480
AAAATGGGCA GCAATCTCAG GACGTACAGA AAAAAGAAAC ATTTCCTAAT GTCGCCGAAG 3540
AGCCCATCTG GAGAATGATA CGGCAGACAC CTGAGCGCAT TCTCATGACA TACCAGGTAC 3600
CTGAGAGGGT TAAAGAAGTT GTACTAAAAG AAGACCTGGA AAAGCTAGAA AGTATGAGGC 3660
AGCAGCAGCC CCAGTTTTCT CATGGGCAAA AGGAGGAGCT GGCTAAGGTG TATAATTGGA 3720
TTCAAAGCCA GACTGTCACT CAAGAAATCG ACATTCAAGC CTGTGTCACT TGTGGAAATG 3780
AAGATTCAGC TGATGGTGCG GCCACATCCT GTGGTCAGGT TCTGGTAGAA GACAGCAGTT 3840
GA 3842
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans28.47 1.10e-14 79.72
CGD-GaG-020965Gallus gallus44.17 0.00e+00 801.6
CGD-HoS-021431Homo sapiens (Human)88.52 0.00e+00 2091.2
CGD-MuM-021078Mus musculus (Mouse)57.45 0.00e+00 1186
CGD-OvA-022195Ovis aries57.41 0.00e+00 1219.1
CGD-RaN-021797Rattus norvegicus58.48 0.00e+00 1213.4
Gene Ontology

GO:0032922--circadian regulation of gene expression
GO:0005515--protein binding
GO:0045187--regulation of circadian sleep/wake cycle, sleep
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0031625--ubiquitin protein ligase binding
GO:0019900--kinase binding
GO:0007623--circadian rhythm