CGDB Gene Information

Tag Content
CGDB ID CGD-MiM-058960
Ensembl Accession ENSMICP00000007691.1
Protein Name PER3
Ensembl Information ENSMICG00000008437; ENSMICT00000008445
Organism Microcebus murinus
NCBI Taxa ID 30608
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 15 ZT 9 LD 6 duodenum Predicted from orthologs E1C8E2
ZT 0 ZT 12 LD 5 pineal gland Predicted from orthologs E1C8E2
ZT 8 ZT 0 LD 4.6 brown adipose tissue Predicted from orthologs O70361
ZT 8 ZT 0 LD 2.46 epididymal white adipose tissue Predicted from orthologs O70361
ZT 12 ZT 0 LD 10 femur vertebra Predicted from orthologs O70361
ZT 8 ZT 4 LD 5.2 heart Predicted from orthologs O70361
ZT 12 ZT 0 LD 35 jejunum Predicted from orthologs O70361
CT 9 CT 21 DD1 2 SCN Predicted from orthologs O70361
ZT 8 ZT 16 LD 2.5 SCN Predicted from orthologs O70361
CT 15 CT 3 DD1 2 testis Predicted from orthologs O70361
CT 15 CT 3 DD1 4 liver Predicted from orthologs O70361
ZT 8 ZT 0 LD 14 lumbar vertebra Predicted from orthologs O70361
CT 0 CT 12 DD2 8.8 NIH-3T3 cells Predicted from orthologs O70361
ZT 8 ZT 0 LD 23 liver Predicted from orthologs O70361
ZT 6 ZT 18 LD 4 muscle Predicted from orthologs W5PL09
ZT 12 ZT 0 LD 25 abdominal adipose tissue Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 2.3 basolateral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 12 ZT 0 LD 5 entral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 4.5 hippocampus Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 14 nucleus accumbens core Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 5 nucleus accumbens shell Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 8 prefrontal cortex Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 6 SCN Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 2 ventral tegmental area Predicted from orthologs Q8CJE2
Descriptionperiod circadian clock 3 [Source:HGNC Symbol;Acc:HGNC:8847](View all)
Protein Sequence
(Fasta)		 MPGGKAPDPR RLEAHEEALC GESEMWSPKF QLQRKYVESS NSEQQDRNRV SEELIMVVQE 60
MKKYFPSERH SKPSTLDALN YALRCVHSVQ ANSEFFQLLS QNGAPQADVT MYSLEELATI 120
ASEHTSKNTD TFVAVFSFLS GRLVHISEQA TLILNYKKDC LESSHFVDLL APQDVRVFYT 180
HTARAQLPFW NNWTQRXXXX XXXXXXXXXX XXXXGGEGRR EQEKYYSPFR IIPYLIHVHS 240
PTHPEPEPCC LTLAEKIHSG YEXXXXXXXX XXXXXXXXXX XXXXXXXXXA VPLLGYLPQD 300
LIGTSILTYL HPEDRSLMVA IHQKVLKYAG HPPFEHSPIR FCTQNGDYII LDSSWSSFVN 360
PSRKVSFIIG RHKVRTSPLN EDVFATRIKK MNSNDKNITE LQQQIHKLLL QPVHVSASSG 420
YGSLGSSGSQ EQQVSAASSS GSSGHCVEEA QREPMTLQQV YASVNKIKNL GQQLYIESMT 480
KSSVKPARGT HTELLGGGKL AXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 540
XXXXXXXYLK SYNIPALKRK CISCANTTSS SSEDDKQNLK ADDVQALQAV SEIPAIPKSE 600
MPTNAWSTDA GGAAPQTLST AALGLGSGVS QCSYSSTLVH VAPTEPAEDA NQFFFFKKTP 660
VSASEEFRSV GLTKAVLSTH TQKEEQNYVD KFREKILSSP YSSYLQQESR SKAKYSYVQG 720
DSTSRQTRSA GCKKGKHKRK KLPAPSGSSS YEAGSGSRAG GAPGHTQPWC PSTAPCPHAS 780
SLALPSAVMI PSQAPYLIPA FPLPATASLG RECAASGTAL ERLPEPPPSS GLMSLPAFPS 840
PYLDTFMTIF LHDIPVCPLL SSALFPHPFL GAAGSFEISA MAPNLGPPPA VTSPRGAEEE 900
WETHSGEHLF INSRSSSPLQ LDLLQEEMPR SSEFSDHMKR DVYLEAEHXX XXXXXXXXXX 960
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 1020
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXSS DSSSDYSSEI SQNGQQSQDA 1080
QKKETFPSLA EESIWRMIQQ TPESILMTYQ VPEXXXXXXX XXXXXXXXXX XXXXXXXXXX 1140
XXXXXXXXXX XXXXXXXXXX XXXXGCVTCD NKASVDDAAE PCGQDPAEDR G 1191
Nucleotide Sequence
(Fasta)		 ATGCCCGGCG GGAAGGCTCC TGACCCCCGG CGACTGGAGG CCCACGAAGA GGCTCTGTGT 60
GGAGAGTCTG AGATGTGGAG CCCCAAGTTC CAGCTGCAGA GGAAATACGT GGAGAGCAGC 120
AACAGTGAAC AGCAAGATCG AAACAGAGTT TCTGAAGAAC TTATAATGGT TGTCCAAGAA 180
ATGAAGAAAT ATTTCCCATC AGAGAGACAC AGTAAGCCAA GCACTCTAGA TGCCCTCAAC 240
TACGCCCTTC GCTGTGTACA CAGTGTGCAA GCAAACAGTG AGTTTTTCCA GCTTCTCAGT 300
CAAAATGGAG CACCTCAAGC AGATGTGACC ATGTACAGTC TTGAGGAGCT GGCCACTATT 360
GCTTCAGAAC ACACTTCCAA AAACACAGAT ACCTTTGTGG CAGTGTTTTC ATTTCTGTCT 420
GGAAGGTTAG TGCACATTTC TGAACAGGCT ACTTTGATCC TGAATTATAA GAAAGATTGC 480
TTGGAGTCCT CTCACTTTGT TGACCTGCTT GCCCCTCAAG ACGTGCGGGT GTTCTACACG 540
CACACTGCCC GAGCTCAGCT CCCCTTCTGG AACAACTGGA CCCAAAGAGN NNNNNNNNNN 600
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NTGGAGGGGA AGGCAGAAGA 660
GAGCAAGAGA AATACTACTC CCCATTCCGG ATTATTCCCT ACTTGATTCA CGTACATAGC 720
CCTACCCATC CAGAGCCAGA ACCTTGCTGT CTCACGCTGG CTGAAAAGAT TCACTCTGGT 780
TATGAAGNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 840
NNNNNNNNNN NNNNNNNNNN NNNNNNAGCG GTGCCTTTGC TGGGTTATCT ACCTCAGGAC 900
CTGATCGGAA CATCCATCTT AACATACTTG CACCCAGAAG ATCGTTCTCT AATGGTTGCT 960
ATACACCAAA AAGTCTTGAA GTATGCAGGC CATCCTCCCT TTGAACATTC TCCCATTAGA 1020
TTTTGTACTC AAAATGGAGA TTACATCATA TTGGATTCCA GTTGGTCCAG CTTTGTGAAC 1080
CCCAGCCGGA AAGTTTCTTT CATCATTGGT CGACATAAAG TTCGAACGAG TCCACTAAAT 1140
GAGGATGTTT TTGCTACCAG AATAAAAAAG ATGAACAGTA ATGACAAAAA CATAACAGAA 1200
TTACAGCAAC AAATTCACAA ACTTCTGTTG CAGCCAGTTC ACGTGAGCGC TTCCAGCGGC 1260
TACGGCAGCC TGGGGAGCAG CGGCTCGCAG GAGCAGCAGG TCAGCGCCGC GTCCTCCAGC 1320
GGGTCCAGCG GGCACTGCGT GGAGGAAGCA CAGAGGGAGC CGATGACCTT GCAGCAGGTC 1380
TATGCCAGTG TAAACAAAAT TAAGAATCTG GGTCAGCAGC TCTACATTGA GTCAATGACC 1440
AAATCATCAG TCAAGCCAGC GAGGGGGACA CACACAGAAC TGCTTGGTGG TGGTAAGTTA 1500
GCAGNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1560
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1620
NNNNNNNNNN NNNNNNNNNN ATACCTGAAG AGCTACAACA TTCCAGCTTT GAAAAGAAAG 1680
TGTATATCCT GTGCAAATAC AACTTCTTCA TCCTCAGAAG ATGACAAACA GAACCTCAAG 1740
GCAGATGATG TCCAAGCATT GCAAGCTGTT TCTGAGATCC CAGCCATACC TAAGTCAGAA 1800
ATGCCAACAA ATGCATGGTC CACAGACGCT GGAGGAGCAG CTCCGCAGAC CTTGTCCACC 1860
GCGGCGCTGG GCCTGGGCTC GGGCGTGAGC CAGTGCAGTT ACAGCAGCAC CCTGGTCCAT 1920
GTCGCACCCA CGGAGCCAGC AGAGGATGCT AATCAGTTTT TTTTTTTTAA AAAGACGCCA 1980
GTCTCGGCCT CTGAAGAATT CAGAAGTGTA GGGCTCACAA AGGCTGTTCT ATCAACCCAC 2040
ACACAGAAGG AAGAACAGAA TTACGTTGAC AAATTCCGGG AAAAGATCCT GTCATCACCC 2100
TACAGCTCAT ATCTTCAGCA AGAAAGCAGA AGCAAAGCTA AATATTCATA TGTTCAAGGA 2160
GATTCTACTT CCAGGCAGAC AAGATCAGCT GGTTGCAAGA AAGGGAAGCA CAAACGCAAG 2220
AAGCTGCCTG CGCCGTCCGG CAGCAGCAGC TATGAAGCTG GCTCCGGCTC CCGTGCCGGG 2280
GGTGCGCCTG GGCACACGCA GCCCTGGTGC CCTTCCACTG CCCCCTGTCC TCACGCCTCC 2340
AGCCTGGCAC TCCCGTCTGC TGTGATGATT CCCAGCCAGG CCCCTTATCT CATCCCAGCT 2400
TTTCCCCTCC CAGCCACGGC CTCTCTGGGG AGAGAATGTG CAGCGTCAGG AACTGCCCTG 2460
GAGCGTCTGC CTGAGCCGCC GCCCTCCAGT GGCTTGATGT CCCTTCCAGC ATTCCCTTCT 2520
CCTTACTTGG ACACTTTTAT GACCATTTTC CTGCATGACA TCCCCGTCTG TCCTCTCTTG 2580
TCATCAGCGC TCTTTCCACA TCCATTCTTG GGAGCAGCAG GCTCTTTTGA AATCTCAGCA 2640
ATGGCTCCAA ACCTAGGGCC ACCACCTGCA GTCACCAGCC CCAGGGGAGC CGAGGAAGAG 2700
TGGGAGACTC ACAGTGGTGA ACACCTGTTT ATTAACTCAA GGAGTAGCTC ACCATTGCAG 2760
CTGGACTTAC TTCAGGAGGA GATGCCCAGG TCTTCTGAAT TCTCAGACCA CATGAAACGA 2820
GATGTTTACC TAGAAGCTGA GCATNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 2880
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 2940
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 3000
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 3060
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 3120
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNGAAGCAGT 3180
GACAGCAGTA GTGATTATTC TTCTGAAATA TCCCAAAATG GGCAGCAATC TCAGGATGCA 3240
CAGAAAAAAG AAACATTTCC CAGTTTAGCT GAAGAGTCCA TCTGGAGGAT GATACAACAA 3300
ACACCCGAGA GCATTCTAAT GACGTATCAG GTACCTGAGA GNNNNNNNNN NNNNNNNNNN 3360
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 3420
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 3480
NNNNNNNNNN NNGGCTGTGT CACTTGTGAC AACAAAGCTT CAGTTGATGA TGCTGCAGAG 3540
CCCTGTGGTC AGGATCCCGC AGAAGACCGC GGCTGA 3576
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-GaG-020965Gallus gallus42.2 4.00e-170 595.5
CGD-MuM-021078Mus musculus (Mouse)54.6 0.00e+00 916.4
CGD-OvA-022195Ovis aries55.72 0.00e+00 940.3
CGD-RaN-021797Rattus norvegicus54.8 0.00e+00 914.1
Gene Ontology

GO:0005515--protein binding
GO:0045187--regulation of circadian sleep/wake cycle, sleep
GO:0007623--circadian rhythm
GO:0019900--kinase binding
GO:0031625--ubiquitin protein ligase binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter