CGDB Gene Information

Tag Content
CGDB ID CGD-MaE-031352
Ensembl Accession ENSMEUP00000009308.1
Protein Name PER3
Ensembl Information ENSMEUG00000010189; ENSMEUT00000010236
Organism Macropus eugenii
NCBI Taxa ID 9315
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
ZT 15 ZT 9 LD 6 duodenum Predicted from orthologs E1C8E2
ZT 0 ZT 12 LD 5 pineal gland Predicted from orthologs E1C8E2
ZT 8 ZT 0 LD 4.6 brown adipose tissue Predicted from orthologs O70361
ZT 8 ZT 0 LD 2.46 epididymal white adipose tissue Predicted from orthologs O70361
ZT 12 ZT 0 LD 10 femur vertebra Predicted from orthologs O70361
ZT 8 ZT 4 LD 5.2 heart Predicted from orthologs O70361
ZT 12 ZT 0 LD 35 jejunum Predicted from orthologs O70361
CT 9 CT 21 DD1 2 SCN Predicted from orthologs O70361
ZT 8 ZT 16 LD 2.5 SCN Predicted from orthologs O70361
CT 15 CT 3 DD1 2 testis Predicted from orthologs O70361
CT 15 CT 3 DD1 4 liver Predicted from orthologs O70361
ZT 8 ZT 0 LD 14 lumbar vertebra Predicted from orthologs O70361
CT 0 CT 12 DD2 8.8 NIH-3T3 cells Predicted from orthologs O70361
ZT 8 ZT 0 LD 23 liver Predicted from orthologs O70361
ZT 6 ZT 18 LD 4 muscle Predicted from orthologs W5PL09
ZT 12 ZT 0 LD 25 abdominal adipose tissue Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 2.3 basolateral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 12 ZT 0 LD 5 entral nucleus of the amygdala Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 4.5 hippocampus Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 14 nucleus accumbens core Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 5 nucleus accumbens shell Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 8 prefrontal cortex Predicted from orthologs Q8CJE2
ZT 0 ZT 12 LD 6 SCN Predicted from orthologs Q8CJE2
ZT 4 ZT 16 LD 2 ventral tegmental area Predicted from orthologs Q8CJE2
Descriptionperiod circadian clock 3 [Source:HGNC Symbol;Acc:HGNC:8847](View all)
Protein Sequence
(Fasta)		 EQQDRNKTSE ELMMVVREMK RHFPSERSHK PSTLEALNYA LRCVHSVQXX XXXXXXXXXX 60
XXXXXXXXXX XXXXXXXXXX XXXXXXXDTF VAVFSFLSGK LVHVSEQATL ILNCKKNSLA 120
SSPFVELLAP QDVRVFYANT AQAHLPFWNV STQTXXXXXX XXXXXXXXXX XXGGKDREQE 180
AHYYPFRITP YVINVYSSAD AEAEPCCLTV VEKIHSGYEA PRIPVNKRIF TTTHTPGCVF 240
LEVDERAVPL LGYLPQDLIG TSVLMYLHPD DRPLMFAVHQ KILKYAGQTP FEHSPVRFCT 300
QNGDYVILDS SWSSFVNPWS RKVSFIIGRH KVRTXXXXXX XXXXXXXKMS SIDKDIIELQ 360
DQIYKLLLQP VHVSGSSGYG SLGSNGSQEH YVSIASSSES SGNCVEEIQK EPMTLQQVCA 420
TVNRIKNLGQ QLYIESRTKL SNQQFVGSGT EQQGGELNKK SSHPSFQELR NSSLGTDSCD 480
DLRKDQHTPS YQQINCVDSI IXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 540
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 600
XXSLSLQTLP VAPEGFRQVG LTKAVLSAHT QKEEKNYVDR FREKILSSPY CSYLQPDGRS 660
KMRYPLIPGD TPSKQAPSAG CKKGKHKRLK LPVSSHSSGS TICLLCWKHH PGRPPWLPSD 720
MTSWLMWGCT LLAPSPATGF PVLPPMSPVR AQCTASVPGL GPHPELSPAY RMQPLPTFPS 780
PYVGAFMTII LHNTPACPQM CQPFSSPCPF WGVPGCSEIV PAPLPSSSPV QPQEDLPELP 840
SPASSQRSAE EEWVLQSDQE HPLFSHSRSS SPLQLNLLQE EMPGAPEPLP PMRQEADTGV 900
QNSMAKGLFT LLLHKDSPTG ADSAASGSSD SSRYFASSDS SSEISQNGQK SEKKEAPHKS 960
GRDAIWGMIE QTPKCILMTY QVPERVKEDV LKEDLEKLES MKQHQPQFTE GQKEELAEVH 1020
PWIQSHTVPR EIDTHGCVTC DSKRSLGVGA LPYEKSLEEH SW 1062
Nucleotide Sequence
(Fasta)		 GAGCAGCAAG ATCGAAACAA GACTTCTGAA GAACTCATGA TGGTGGTCCG AGAAATGAAA 60
AGGCATTTCC CCTCTGAGCG AAGTCACAAA CCGAGTACTC TGGAGGCCCT CAACTACGCC 120
CTTCGCTGCG TGCACAGTGT TCAAGNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 180
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 240
NNNNNNNNNN NNNNNNNNNN NGATACCTTT GTGGCGGTTT TTTCATTTCT GTCGGGAAAG 300
TTGGTACATG TTTCGGAGCA AGCTACTCTT ATTCTAAACT GCAAGAAGAA TTCCCTGGCA 360
TCCTCTCCAT TTGTCGAGCT GCTTGCCCCT CAAGATGTGA GGGTGTTCTA TGCAAACACG 420
GCCCAGGCCC ATCTTCCATT CTGGAATGTC AGCACCCAAA CAGNNNNNNN NNNNNNNNNN 480
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNGGGAG GTAAAGACCG AGAACAAGAG 540
GCCCATTATT ATCCATTCCG GATCACCCCC TATGTGATCA ACGTATACAG TTCTGCTGAT 600
GCAGAGGCCG AACCGTGCTG CCTCACTGTG GTCGAGAAGA TCCACTCTGG TTATGAAGCT 660
CCCCGGATTC CCGTGAATAA AAGGATCTTT ACAACAACCC ATACCCCAGG GTGTGTGTTT 720
CTTGAAGTGG ATGAAAGAGC TGTGCCTTTG TTGGGCTACC TCCCTCAGGA CCTGATTGGA 780
ACCTCCGTCT TAATGTACCT GCATCCAGAT GACCGTCCTC TGATGTTTGC TGTGCACCAA 840
AAAATCTTGA AGTATGCAGG CCAAACTCCC TTTGAACATT CACCTGTTAG ATTTTGCACT 900
CAGAATGGAG ATTATGTCAT ATTGGATTCC AGCTGGTCCA GCTTTGTGAA CCCGTGGAGC 960
CGGAAAGTTT CCTTCATCAT TGGCCGACAC AAAGTCCGGA CNNNNNNNNN NNNNNNNNNN 1020
NNNNNNNNNN NNNNNNNNNN NAAGATGAGC AGTATTGATA AAGATATAAT AGAATTACAA 1080
GATCAAATTT ACAAACTTCT CTTACAGCCA GTTCACGTCA GTGGGTCCAG CGGCTATGGC 1140
AGCCTGGGAA GCAATGGGTC ACAGGAACAT TACGTTAGCA TTGCGTCATC TAGCGAGTCC 1200
AGTGGAAACT GTGTGGAGGA AATACAGAAG GAGCCGATGA CATTGCAGCA GGTCTGTGCC 1260
ACTGTCAACA GAATCAAAAA CCTGGGTCAG CAGCTGTATA TTGAATCGAG GACCAAATTA 1320
TCAAACCAAC AGTTTGTAGG ATCAGGTACA GAGCAACAAG GAGGTGAGTT AAACAAGAAG 1380
TCTTCTCATC CTTCATTTCA GGAGCTGAGA AATAGTAGTT TGGGCACCGA TTCTTGTGAT 1440
GACTTAAGAA AAGATCAGCA TACTCCATCC TATCAGCAGA TCAATTGTGT GGACAGCATT 1500
ATCAGNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1560
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1620
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1680
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1740
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1800
NNNNGAAGCC TGAGCCTTCA GACTTTGCCT GTGGCCCCAG AGGGCTTCAG GCAGGTAGGG 1860
CTCACAAAAG CAGTGCTCTC TGCTCACACA CAGAAGGAGG AGAAGAACTA TGTGGACAGA 1920
TTTCGGGAAA AGATCCTGTC TTCTCCATAT TGCTCCTACC TTCAGCCAGA TGGCAGAAGC 1980
AAGATGAGAT ATCCCCTCAT CCCAGGAGAC ACTCCTTCCA AGCAGGCCCC GTCAGCTGGC 2040
TGTAAAAAGG GGAAACACAA GCGCCTGAAG CTGCCGGTGT CCTCTCACAG CAGTGGCTCG 2100
ACAATTTGCC TTCTCTGCTG GAAACACCAT CCGGGCAGAC CACCCTGGTT GCCTTCAGAC 2160
ATGACCTCCT GGCTCATGTG GGGCTGCACC CTCTTGGCCC CCTCCCCGGC CACTGGCTTT 2220
CCTGTTCTGC CCCCCATGTC CCCTGTGAGA GCACAGTGCA CAGCATCCGT TCCTGGACTG 2280
GGACCTCATC CGGAGTTAAG CCCTGCCTAC AGGATGCAGC CGCTGCCAAC ATTCCCTTCT 2340
CCTTATGTGG GTGCTTTTAT GACCATTATT TTGCACAACA CCCCTGCCTG TCCCCAGATG 2400
TGCCAACCAT TCTCTTCCCC CTGTCCGTTC TGGGGTGTGC CTGGTTGCTC TGAAATAGTC 2460
CCAGCGCCAC TACCCTCCTC ATCACCAGTG CAGCCGCAGG AGGACCTTCC AGAGCTGCCA 2520
TCCCCAGCCT CTAGCCAGAG ATCGGCTGAA GAGGAGTGGG TGCTCCAGAG TGATCAGGAG 2580
CATCCCTTAT TTAGTCATTC CAGGAGCAGC TCCCCACTAC AGCTGAACCT GCTTCAGGAA 2640
GAAATGCCAG GGGCTCCCGA GCCTTTGCCA CCCATGAGAC AGGAGGCAGA TACAGGAGTG 2700
CAGAATTCTA TGGCCAAGGG ACTGTTTACA CTGTTACTTC ACAAGGACTC TCCAACTGGA 2760
GCTGATTCTG CAGCATCAGG AAGCAGCGAT AGCAGCAGAT ACTTTGCAAG TAGCGACTCT 2820
TCCTCTGAAA TCTCCCAGAA TGGGCAGAAA TCAGAGAAGA AAGAAGCACC CCACAAATCA 2880
GGTAGAGATG CCATCTGGGG CATGATAGAG CAGACCCCCA AGTGCATCCT GATGACGTAT 2940
CAGGTCCCCG AGAGGGTTAA AGAAGATGTA TTAAAAGAGG ACCTAGAGAA GCTGGAAAGT 3000
ATGAAACAGC ATCAACCTCA GTTTACGGAA GGACAGAAAG AGGAGTTGGC AGAAGTGCAC 3060
CCTTGGATTC AAAGCCACAC GGTCCCTCGA GAAATAGACA CCCATGGCTG TGTCACGTGT 3120
GACAGCAAAC GCTCGCTGGG TGTCGGGGCT CTGCCTTATG AGAAGAGTCT GGAAGAACAC 3180
AGTTGGTGA 3189
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans30.17 8.60e-14 76.64
CGD-GaG-020965Gallus gallus57.11 2.00e-154 543.1
CGD-MuM-021078Mus musculus (Mouse)60.16 2.00e-162 571.2
CGD-OvA-022195Ovis aries57.8 2.00e-161 566.6
CGD-RaN-021797Rattus norvegicus60.08 3.00e-167 586.6
Gene Ontology

GO:0005515--protein binding
GO:0045187--regulation of circadian sleep/wake cycle, sleep
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0031625--ubiquitin protein ligase binding
GO:0019900--kinase binding
GO:0007623--circadian rhythm