CGDB Gene Information

Tag Content
CGDB ID CGD-OcP-070087
Ensembl Accession ENSOPRP00000015483.2
Protein Name PER1
Ensembl Information ENSOPRG00000016943; ENSOPRT00000016958
Organism Ochotona princeps
NCBI Taxa ID 9978
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 21 ZT 9 LD 6 duodenum Predicted from orthologs Q8QGQ8
ZT 2 ZT 18 LD 3.17 embryos Predicted from orthologs Q8QGQ8
ZT 6 ZT 18 LD 8 embryos Predicted from orthologs Q8QGQ8
CT 12 CT 0 DD1 3 granulosa cells Predicted from orthologs Q8QGQ8
ZT 3 ZT 18 LD 84.29 pineal glands Predicted from orthologs Q8QGQ8
ZT 23 ZT 11 LD 2.25 spleen Predicted from orthologs Q8QGQ8
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSGPVRADGG GDPRPGSFRA GEEAFGADRE GPEFDGATRR XXXXXXXXXX XXXXXXXXXX 60
XXXXTNSQSP SPPSSSIAYS LLSASSEQDN PSTSGCSSEQ SARARTQKEL MTALRELKLR 120
LPPERRGKGR SGTLATLQYA LACVKQVQAN QEYYQQWSLE EGEPCAMDMS TYTLEELEHI 180
TSEYTLRNQD TFSVAVSFLT GRIVYISEQA AILLRCKRDV FRGARFSELL APQDVGVFYG 240
STAPSRLPTW GAGASAGSHL KDFTQEKSIF CRIPDRDPGP RYQPFRLTPY VTKIRVSDGA 300
PAQPCCLLIA ERIHSGYEAP RIPPDKRIFT TRHTPSCLFQ DVDERAAPLL GYLPQDLLGA 360
PVLLFLHPED RPLMLAIHKK ILQLAGQPFD HSPIRFCARN GEYVTMDTSW AGFVHPWSRK 420
VAFVLGRHKV RTAPLNEDVF TPPAPNPALS LDSDIHELSE QIHRLLLQPV HSSSPTGICG 480
LGPLTSPGPL HSPGSSSDSN GGDAEGPGPP VPVTFQQICK DVHLVKHQGQ QLFIESRARP 540
PPRPRLPATG TFKAKALGSQ SPDPELEVSP APVQAPLAFV PEEAEQKEAS TCSYQQINCL 600
DSILRYLESC NIPSTTKRKC ASSSSCTASS ASDDDKQRTG TGPVPTGAKK DPAAAAGVFS 660
GEGATPRKEP VVGGSLSPLA LANKAESVAS VTSQCSFSST IVHVGDKKPP ESDIIMEDLP 720
GLAPGLAPSP APSPTVAPDP APDAYRPVGL TKAVLSLHTQ KEEQAFLSRF RDLGHLRRLD 780
GSSTTPSAPG ERGCHHGPAP PGRRHHCRSK AKRSRHHQTA RAEAPCYVPH PSPVPTSATW 840
PPPQATTPFP AVVQPYALPV FSPRGPQALP PASTSVPPAT FPAPVTPMXX XXXXXXXXXX 900
XXXXXXXXXQ SPAEGPPTPA SHSPSPSLPP LPPSPPPHPD SPLFQSRCSS PLQLNLLQLE 960
EPPRTEGAAV AGGPGSSAGP PPPSEEAAEP EARMVEVTES SNQDALFGSS DLLELLLQKD 1020
SRSGTGSAAS GSLGSGLGSG SGSGSHEGGS TSASITRSSQ SSHTSKYFGS VESSEAEAGA 1080
ARVGAEPGEQ VIKYVLQDPI WLLMANADQR VMMTYQVPSR DMASVLKLDR ERLRAMQKQQ 1140
PRFSEEQRRE LGAVHSWVRK GQLPRALDVM ACVDCGSSAQ DPGQPEDPLF SELDGLGLEP 1200
MEEGGGEGGG GGGAGGDGSG EGEGGEEAQA QVGVKVSSSQ DQDAAMEEEE QGGSSSGPAL 1260
RSEEEDGTS 1269
Nucleotide Sequence
(Fasta)		 ATGAGTGGCC CCGTAAGGGC TGATGGGGGT GGGGATCCCA GACCCGGGTC CTTCCGTGCA 60
GGGGAGGAAG CGTTTGGTGC CGACCGCGAA GGACCCGAGT TTGATGGAGC GACTCGGCGG 120
ANNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 180
NNNNNNNNNN NCACAAACTC TCAGAGCCCC TCCCCGCCCA GCAGTTCCAT CGCTTACAGC 240
CTGCTGAGCG CCAGCTCAGA GCAGGACAAC CCATCTACCA GTGGCTGCAG CAGTGAGCAG 300
TCAGCGCGGG CGAGGACCCA GAAGGAACTC ATGACTGCGC TGCGGGAGCT CAAGCTCCGG 360
CTGCCGCCAG AGCGCCGGGG CAAAGGCCGC TCTGGCACGT TGGCCACGCT GCAGTATGCG 420
CTGGCCTGCG TGAAGCAGGT GCAGGCTAAC CAGGAGTACT ACCAGCAGTG GAGCCTGGAG 480
GAAGGGGAGC CCTGTGCCAT GGACATGTCT ACTTACACCT TGGAGGAGCT GGAGCACATC 540
ACATCAGAGT ACACACTTCG TAACCAGGAC ACCTTCTCGG TGGCGGTCTC CTTCCTGACA 600
GGCCGGATCG TCTACATCTC CGAGCAGGCA GCTATCCTGC TGCGCTGCAA GCGGGATGTG 660
TTCCGAGGCG CCCGCTTCTC TGAGCTCCTG GCTCCGCAGG ATGTGGGTGT CTTCTATGGC 720
TCCACCGCCC CATCCCGACT GCCCACCTGG GGTGCTGGGG CCTCAGCAGG TTCACACCTC 780
AAGGACTTCA CCCAAGAGAA GTCTATCTTT TGCCGTATCC CTGACCGGGA CCCAGGACCT 840
CGGTACCAGC CATTCCGTCT AACTCCCTAC GTGACCAAGA TCCGGGTGTC TGATGGGGCC 900
CCCGCCCAGC CGTGCTGCCT GCTCATTGCA GAGCGTATCC ACTCGGGTTA TGAAGCTCCC 960
CGGATCCCTC CGGATAAGAG GATCTTTACC ACGCGCCACA CACCCAGCTG CCTCTTCCAG 1020
GACGTGGACG AGAGGGCTGC TCCGCTGCTG GGCTACCTGC CCCAAGACCT GCTCGGCGCC 1080
CCAGTCCTCC TGTTCCTACA CCCAGAGGAC CGGCCCCTCA TGTTGGCCAT CCACAAGAAG 1140
ATTCTACAGC TGGCAGGCCA GCCCTTCGAC CACTCCCCTA TCCGCTTCTG TGCCCGTAAT 1200
GGGGAGTACG TCACCATGGA CACCAGCTGG GCTGGCTTTG TCCACCCCTG GAGCCGCAAG 1260
GTGGCCTTTG TGTTGGGCCG CCATAAAGTA CGCACGGCAC CCCTGAACGA GGATGTGTTC 1320
ACACCTCCGG CCCCCAACCC AGCTCTGTCC TTGGACTCTG ATATCCACGA GCTGTCCGAG 1380
CAGATCCACC GGTTGCTGCT GCAGCCCGTG CATAGCTCTA GCCCCACGGG GATCTGTGGC 1440
CTTGGCCCCT TGACGTCCCC AGGCCCTCTC CACAGCCCTG GCTCCTCCAG TGACAGCAAC 1500
GGGGGTGATG CTGAGGGGCC TGGACCTCCG GTTCCAGTGA CTTTCCAGCA GATCTGTAAG 1560
GACGTGCATC TGGTGAAGCA CCAGGGACAG CAGCTCTTCA TTGAGTCCCG GGCCCGGCCC 1620
CCGCCTCGGC CCCGCCTCCC TGCCACAGGC ACATTCAAGG CCAAGGCCCT TGGCAGCCAG 1680
TCCCCAGACC CGGAGCTGGA GGTGAGCCCT GCTCCCGTCC AGGCCCCACT AGCCTTCGTG 1740
CCTGAGGAGG CTGAACAGAA GGAGGCCTCC ACTTGCTCCT ACCAACAGAT CAACTGCCTG 1800
GACAGCATCC TCAGGTACCT GGAGAGCTGC AACATCCCCA GCACAACCAA GCGCAAGTGT 1860
GCCTCCTCTT CCTCCTGTAC TGCCTCATCG GCCTCCGATG ATGACAAGCA GAGGACAGGG 1920
ACGGGTCCAG TCCCCACAGG AGCCAAGAAA GATCCTGCAG CGGCGGCGGG CGTGTTCTCT 1980
GGGGAGGGGG CGACTCCACG GAAGGAGCCC GTGGTGGGAG GCAGCCTGAG CCCGCTCGCG 2040
CTGGCCAATA AGGCAGAGAG CGTGGCGTCC GTCACCAGTC AGTGTAGCTT CAGCTCCACC 2100
ATCGTCCATG TGGGAGACAA GAAGCCCCCG GAGTCGGACA TCATCATGGA GGATCTGCCT 2160
GGCCTAGCCC CGGGCCTGGC CCCCAGTCCA GCCCCCAGCC CCACAGTAGC CCCTGACCCG 2220
GCTCCAGACG CCTACCGCCC TGTGGGCTTG ACCAAGGCCG TGCTGTCCCT GCACACACAG 2280
AAGGAAGAGC AAGCCTTTCT CAGTCGTTTC CGGGACCTTG GGCACCTGCG CAGACTCGAT 2340
GGCTCTTCCA CAACCCCTTC AGCCCCGGGC GAGCGAGGCT GCCACCATGG CCCTGCGCCC 2400
CCTGGCCGCC GCCACCACTG CCGGTCTAAA GCCAAGCGCT CACGCCACCA CCAGACTGCC 2460
CGAGCTGAAG CCCCTTGCTA TGTTCCCCAC CCCTCACCTG TGCCCACCTC TGCCACCTGG 2520
CCCCCGCCAC AAGCCACCAC CCCCTTCCCT GCAGTGGTCC AGCCCTATGC CCTCCCTGTG 2580
TTCTCCCCTC GGGGACCCCA GGCTCTGCCC CCGGCTTCCA CGTCTGTACC CCCTGCCACT 2640
TTCCCTGCCC CCGTGACCCC TATGGNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 2700
NNNNNNNNNN NNNNNNNNNN NNNNNNNCAG AGCCCAGCAG AGGGACCTCC AACCCCTGCC 2760
TCCCACTCCC CCTCGCCATC CCTGCCTCCT CTGCCTCCCA GCCCCCCACC ACACCCAGAC 2820
TCCCCACTGT TCCAGTCGAG ATGCAGCTCT CCACTCCAGC TGAACCTGCT ACAGCTGGAG 2880
GAGCCCCCCC GTACTGAGGG GGCTGCTGTG GCAGGGGGTC CTGGGAGCAG TGCTGGGCCC 2940
CCACCTCCCA GTGAGGAGGC AGCTGAGCCA GAGGCCAGAA TGGTGGAGGT GACTGAGTCC 3000
TCCAATCAGG ACGCGCTTTT CGGCTCCAGT GACCTGCTGG AGCTGCTGCT GCAGAAGGAC 3060
TCGCGCTCGG GTACCGGCTC TGCGGCCTCC GGCTCCCTGG GCTCTGGCCT AGGCTCTGGG 3120
TCCGGATCAG GCTCCCATGA GGGGGGCAGC ACCTCAGCCA GCATCACCCG CAGCAGTCAG 3180
AGCAGCCACA CAAGCAAGTA CTTTGGCAGC GTCGAGTCTT CGGAGGCCGA GGCTGGGGCT 3240
GCGCGGGTCG GGGCTGAGCC TGGGGAGCAG GTCATTAAGT ATGTACTCCA GGATCCCATT 3300
TGGCTGCTCA TGGCCAATGC TGACCAGCGT GTCATGATGA CCTACCAGGT GCCCTCCAGG 3360
GACATGGCGT CTGTGCTGAA GCTGGACCGG GAGCGGCTGC GGGCCATGCA GAAGCAGCAG 3420
CCTCGGTTCT CTGAGGAGCA GCGGCGGGAA CTAGGGGCTG TGCACTCCTG GGTCCGGAAG 3480
GGCCAGCTTC CTCGAGCCCT CGATGTGATG GCCTGCGTGG ACTGTGGGAG CAGTGCCCAA 3540
GACCCTGGTC AACCTGAAGA TCCTCTCTTC TCGGAGCTGG ATGGACTGGG CCTGGAGCCC 3600
ATGGAGGAGG GGGGAGGCGA GGGTGGTGGT GGTGGTGGGG CTGGGGGTGA CGGCAGTGGT 3660
GAGGGGGAGG GTGGTGAGGA GGCCCAGGCC CAGGTGGGGG TCAAGGTCTC AAGCTCCCAG 3720
GACCAGGATG CGGCCATGGA GGAGGAGGAG CAAGGTGGGA GCTCATCTGG TCCAGCCTTA 3780
CGGTCCGAGG AGGAGGACGG CACCAGCTAG
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans26.01 2.70e-14 78.57
CGD-EqC-020994Equus caballus61.1 0.00e+00 1394.8
CGD-GaM-021007Gadus morhua53.3 0.00e+00 633.3
CGD-GaG-021834Gallus gallus43 4.00e-173 605.5
CGD-HoS-021038Homo sapiens (Human)63.1 0.00e+00 1418.7
CGD-OvA-022197Ovis aries61.86 0.00e+00 1372.1
CGD-RaN-021793Rattus norvegicus62.29 0.00e+00 1389
Gene Ontology

GO:0005515--protein binding
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0032922--circadian regulation of gene expression
GO:0051591--response to cAMP
GO:0007623--circadian rhythm
GO:0019900--kinase binding
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0043966--histone H3 acetylation
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0043967--histone H4 acetylation
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm