CGDB Gene Information

Tag Content
CGDB ID CGD-SoA-065078
Ensembl Accession ENSSARP00000005109.1
Protein Name PER1
Ensembl Information ENSSARG00000005605; ENSSART00000005640
Organism Sorex araneus
NCBI Taxa ID 42254
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 21 ZT 9 LD 6 duodenum Predicted from orthologs Q8QGQ8
ZT 2 ZT 18 LD 3.17 embryos Predicted from orthologs Q8QGQ8
ZT 6 ZT 18 LD 8 embryos Predicted from orthologs Q8QGQ8
CT 12 CT 0 DD1 3 granulosa cells Predicted from orthologs Q8QGQ8
ZT 3 ZT 18 LD 84.29 pineal glands Predicted from orthologs Q8QGQ8
ZT 23 ZT 11 LD 2.25 spleen Predicted from orthologs Q8QGQ8
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSSSQEGADG GGDSRTRESF CPGGTPSPGP PQHLPCPDPN LADDMDANSN GSSGNESNGP 60
ESRGASQRSS QSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSVAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCVMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGR IVYISEQAGI 240
LLRCKRDVFQ GARFSEFLAP QDVGIFYGST APSRLPIWGA GASEGSGTRD FTQEKSVFCR 300
IRGGPDRDPG PRYQPFRLIP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPTPSPAL 480
SLDPDIQELS EQIHRLLLQP VHSPPTGLCG VGPVTSPGPL LSPGSSSESN GGDTEGPGPP 540
APVTFQQICK DVHLVKHQGQ QVFIESRTRP LNRPRLPTTG AFKARTFPCR SPDPELESAP 600
SSQTPLAVVP EEAERKEASG CSYQQINCLD SILRYLESCS IPGTTKRKCA SSSSCTASSA 660
SDDDKQKTGP VPVGARKDPA SAVLSGEGAT PRKEPVVGGT LSPLALANKA ESVVSITSQC 720
SFSSTIVHVG DKKPPESDIV MMEDLPGLAS GPALSPAVAP DPVPDAYRPV GLTKAVLSLH 780
TQKEEQAFLS RFRDLGRLRG LHSSSMAPSA PGEGCHHGPE PSGRRHHCRS KAKRSRHHQT 840
PRTEAPCYVS HPSTMPSSAP WAPPPATTPF PAVVQPYPLP VFSPRGGPQP LPPSPTSMSS 900
TTFSAPLVTP MVALVLPNCL FPTPTSYPCG VPQTSAEGPT TPASHSPPSS LPLLPPSPTH 960
HPEAPLFNSR CSSPLQLNLL QLEETARVEG GAVAGGSGDS AGPPPPSEEA AEPEARLVEV 1020
TESSNQDALS GSSDLLELLL QVDSHSGTGS AASGSLGSAM GAGSGSGSQE WGSTSASITR 1080
DSQSSHTSKY FGSIDSSEAE AGVAQGRVEP GDQVIKYVLQ DPIWLLMANA DQHVMMTYQV 1140
PSRDMASVLK KDREQLRAMQ KQQPRFSEEQ RRELGAVHSW VWKGQLPRAL DVMACVDCGS 1200
STQDRGQHDD PLFTELDGLG LEPMEEGGGE GGGTGEGGNE TQTQFGTRVS SSQDLAMEEE 1260
EQGGSSSSRA LTATENGTS 1279
Nucleotide Sequence
(Fasta)		 ATGAGTAGCT CCCAAGAAGG GGCTGATGGG GGAGGGGACT CCAGGACCAG GGAATCCTTT 60
TGTCCTGGAG GGACCCCATC CCCTGGGCCT CCTCAGCATC TGCCTTGTCC AGACCCCAAC 120
CTGGCTGATG ATATGGATGC CAATAGCAAT GGCTCAAGTG GCAATGAGTC CAATGGGCCA 180
GAGTCCAGGG GTGCGTCTCA GCGGAGCTCA CAAAGTTCCT CCTCGGGCAA TGGCAAGGAC 240
TCAGCCCTGC TGGAGACCAC CGAGAGCAGC AAGAGTACAA ACTCTCAGAG CCCATCCCCA 300
CCCAGCAGTT CCGTTGCCTA CAGTCTCCTG AGTGCCAGCT CAGAGCAGGA TAACCCATCT 360
ACCAGTGGCT GCAGCAGTGA GCAGTCAGCT CGGGCAAGGA CTCAGAAGGA ACTCATGACA 420
GCACTTCGAG AGCTTAAGCT TCGACTGCCA CCAGAGCGCC GGGGCAAGGG CCGCTCTGGG 480
ACTCTGGCCA CACTACAGTA TGCGCTGGCC TGTGTCAAGC AAGTGCAAGC CAACCAAGAA 540
TACTACCAAC AGTGGAGCCT GGAGGAGGGG GAGCCTTGTG TTATGGACAT GTCCACCTAT 600
ACTCTGGAGG AACTGGAGCA CATCACGTCT GAGTATACAC TTCGCAACCA GGACACCTTC 660
TCCGTGGCTG TCTCCTTCCT GACAGGCCGC ATTGTCTACA TTTCGGAGCA AGCAGGTATC 720
CTGCTACGCT GCAAGCGGGA TGTGTTCCAG GGTGCCCGCT TCTCAGAGTT CCTGGCTCCC 780
CAGGATGTGG GCATTTTCTA TGGTTCCACT GCTCCATCCC GTCTGCCCAT CTGGGGTGCC 840
GGGGCTTCAG AAGGTTCAGG CACTAGGGAT TTCACCCAGG AGAAGTCTGT CTTCTGCCGT 900
ATCAGAGGAG GTCCTGACCG GGATCCAGGG CCTCGTTACC AGCCATTCCG CCTAATTCCA 960
TATGTCACCA AGATCCGGGT CTCAGATGGA GCCCCTGCTC AACCATGTTG CCTGCTTATT 1020
GCAGAGCGCA TCCACTCGGG TTATGAAGCT CCTAGGATCC CTCCTGACAA AAGGATCTTC 1080
ACCACACGAC ACACGCCTAG CTGCCTCTTC CAGGATGTGG ATGAAAGGGC TGCCCCGCTG 1140
CTGGGCTATC TCCCTCAGGA CCTCCTGGGG GCCCCAGTGC TTCTGTTCCT GCATCCGGAG 1200
GACCGACCCC TGATGCTGGC AATCCACAAG AAAATTCTGC AGCTGGCGGG CCAGCCCTTT 1260
GATCACTCCC CCATTCGCTT CTGTGCCCGA AATGGGGAGT ATGTCACCAT GGATACCAGC 1320
TGGGCTGGCT TCGTGCACCC CTGGAGCCGA AAGGTAGCCT TTGTTTTAGG CCGCCACAAA 1380
GTACGCACGG CACCTCTGAA TGAGGACGTG TTCACTCCTC CTACTCCCAG CCCAGCATTG 1440
TCCCTTGACC CTGATATCCA GGAGCTATCT GAGCAGATCC ATCGGCTGCT GTTACAGCCT 1500
GTGCACAGCC CCCCCACAGG GCTCTGTGGA GTTGGTCCTG TGACTTCCCC AGGCCCTCTC 1560
CTCAGCCCTG GCTCCTCCAG TGAGAGCAAC GGGGGAGACA CCGAGGGGCC TGGCCCTCCT 1620
GCCCCGGTGA CCTTCCAGCA GATCTGTAAG GATGTCCATC TGGTGAAGCA CCAGGGCCAG 1680
CAGGTCTTCA TTGAGTCCCG CACCCGGCCA CTAAACCGGC CTCGCCTCCC TACTACAGGC 1740
GCATTCAAAG CTAGGACCTT TCCCTGCCGG TCCCCAGACC CAGAGTTGGA GTCAGCTCCT 1800
TCCAGCCAGA CCCCTCTAGC TGTGGTCCCT GAAGAGGCAG AGAGGAAGGA AGCCTCTGGT 1860
TGTTCCTACC AACAGATCAA CTGCCTGGAC AGCATTCTTA GGTACCTAGA GAGCTGCAGC 1920
ATTCCTGGCA CGACCAAGCG TAAATGTGCC TCCTCTTCCT CCTGTACTGC ATCCTCAGCC 1980
TCTGATGATG ACAAGCAGAA GACAGGGCCA GTCCCTGTGG GGGCCAGGAA AGATCCGGCA 2040
TCAGCAGTGC TGTCTGGGGA GGGGGCCACT CCTCGGAAGG AGCCAGTGGT GGGTGGCACC 2100
CTGAGCCCGC TCGCCCTGGC CAATAAGGCA GAGAGCGTGG TGTCCATCAC CAGTCAGTGT 2160
AGCTTCAGCT CCACCATCGT CCATGTGGGA GACAAGAAGC CCCCGGAGTC GGACATTGTC 2220
ATGATGGAGG ACCTGCCTGG GCTAGCTTCA GGCCCAGCCC TCAGCCCTGC AGTAGCCCCT 2280
GACCCCGTCC CAGACGCTTA CCGCCCAGTG GGTTTGACCA AGGCAGTTCT GTCCCTGCAC 2340
ACACAGAAGG AGGAGCAGGC CTTCCTCAGC CGCTTCCGTG ACCTGGGTAG GCTGCGTGGC 2400
CTCCACAGCT CCTCCATGGC TCCCTCGGCC CCTGGTGAGG GCTGCCACCA TGGCCCTGAG 2460
CCCTCTGGCC GCCGACACCA CTGCCGATCC AAAGCCAAGC GCTCACGCCA CCACCAGACT 2520
CCCCGGACCG AAGCCCCCTG CTATGTCTCC CACCCCTCGA CTATGCCATC CTCTGCCCCT 2580
TGGGCCCCAC CACCAGCTAC TACTCCCTTC CCAGCTGTGG TCCAGCCCTA CCCTCTTCCA 2640
GTATTCTCTC CGAGAGGAGG CCCCCAGCCT CTTCCCCCTT CCCCTACATC CATGTCCTCT 2700
ACAACTTTCT CTGCCCCCCT GGTGACCCCG ATGGTGGCCT TGGTACTCCC TAACTGTCTG 2760
TTCCCTACTC CAACCAGTTA CCCTTGTGGG GTGCCCCAGA CTTCTGCCGA GGGGCCTACA 2820
ACTCCTGCCT CCCATTCTCC TCCTTCGTCT CTGCCCCTTC TGCCCCCCAG CCCTACTCAC 2880
CACCCAGAAG CTCCATTATT CAATTCGAGA TGTAGCTCCC CACTCCAGCT AAATCTGCTG 2940
CAGCTTGAGG AGACCGCCCG AGTTGAGGGG GGTGCTGTTG CAGGGGGCTC TGGGGACAGT 3000
GCTGGGCCCC CGCCTCCCAG TGAGGAGGCT GCTGAGCCAG AGGCCAGACT GGTGGAGGTG 3060
ACTGAGTCCT CCAATCAGGA TGCACTTTCG GGCTCCAGTG ATCTGCTGGA GTTGCTGCTG 3120
CAGGTGGACT CTCACTCGGG CACAGGCTCT GCTGCCTCGG GCTCCTTGGG CTCTGCCATG 3180
GGCGCTGGAT CCGGTTCAGG CTCTCAGGAG TGGGGCAGCA CTTCAGCCAG CATCACACGT 3240
GACAGTCAGA GCAGCCACAC AAGCAAGTAC TTTGGCAGCA TCGACTCTTC CGAGGCAGAG 3300
GCTGGAGTTG CCCAGGGTAG GGTTGAGCCT GGGGATCAGG TCATCAAGTA TGTGCTCCAG 3360
GATCCCATCT GGCTGCTCAT GGCCAATGCT GACCAGCATG TCATGATGAC TTACCAGGTG 3420
CCGTCCAGGG ACATGGCCTC TGTATTGAAA AAGGATCGGG AGCAACTCCG GGCCATGCAG 3480
AAGCAGCAAC CGCGATTTTC AGAAGAGCAG CGGAGAGAGC TGGGTGCCGT GCACTCCTGG 3540
GTCTGGAAGG GCCAACTGCC TCGGGCTCTC GATGTGATGG CCTGTGTGGA CTGTGGCAGT 3600
AGCACCCAAG ACCGTGGCCA GCATGATGAC CCACTCTTCA CGGAGCTCGA TGGACTGGGG 3660
CTGGAGCCTA TGGAGGAGGG TGGAGGCGAG GGTGGCGGCA CTGGTGAAGG TGGAAATGAG 3720
ACCCAGACCC AATTTGGGAC CAGGGTCTCA AGCTCTCAGG ACTTGGCTAT GGAGGAGGAA 3780
GAACAAGGTG GGAGCTCATC CAGTCGAGCC TTAACTGCCA CAGAAAATGG CACAAGCTAA 3840
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans26.32 7.30e-15 80.49
CGD-EqC-020994Equus caballus66.67 0.00e+00 1615.5
CGD-GaM-021007Gadus morhua53.28 4.00e-180 629
CGD-GaG-021834Gallus gallus42.41 2.00e-177 620.2
CGD-HoS-021038Homo sapiens (Human)66.46 0.00e+00 1620.5
CGD-OvA-022197Ovis aries67.1 0.00e+00 1551.2
CGD-RaN-021793Rattus norvegicus68.44 0.00e+00 1597.4
Gene Ontology

GO:0007165--signal transduction
GO:0004871--signal transducer activity
GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0005515--protein binding
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0051591--response to cAMP
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus