CGDB Gene Information

Tag Content
CGDB ID CGD-OtG-040337
Ensembl Accession ENSOGAP00000005581.2
Protein Name PER2
Ensembl Information ENSOGAG00000006245; ENSOGAT00000006251
Organism Otolemur garnettii
NCBI Taxa ID 30611
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
ZT 6 ZT 18 LD 5 skeletal muscle Predicted from orthologs F6ZZH0
ZT 21 ZT 9 LD 6 duodenum Predicted from orthologs Q8QGQ8
ZT 2 ZT 18 LD 3.17 embryos Predicted from orthologs Q8QGQ8
ZT 6 ZT 18 LD 8 embryos Predicted from orthologs Q8QGQ8
CT 12 CT 0 DD1 3 granulosa cells Predicted from orthologs Q8QGQ8
ZT 3 ZT 18 LD 84.29 pineal glands Predicted from orthologs Q8QGQ8
ZT 23 ZT 11 LD 2.25 spleen Predicted from orthologs Q8QGQ8
CT 4 CT 12 DD2 27 aortic smooth muscle cells Predicted from orthologs O15055
ZT 4 ZT 21 LD 5 human HaCaT keratinocytes Predicted from orthologs O15055
ZT 1 ZT 19 LD 2.67 human hair follicle cells Predicted from orthologs O15055
CT 12 CT 0 LL1 3.43 oral mucosa Predicted from orthologs O15055
CT 3 CT 15 DD2 5 U2OS cells Predicted from orthologs O15055
CT 6 CT 18 DD1 4 SCN Predicted from orthologs O54943
CT 9 CT 3 DD1 3 eye Predicted from orthologs O54943
ZT 19 ZT 7 LD 2.5 amygdala Predicted from orthologs O54943
ZT 12 ZT 4 LD 2 bone Predicted from orthologs O54943
ZT 13 ZT 5 LD 2.4 bone marrow Predicted from orthologs O54943
ZT 18 ZT 6 LD 1.89 brain Predicted from orthologs O54943
ZT 15 ZT 23 LD 3 cortex Predicted from orthologs O54943
ZT 13 ZT 2 LD 10 heart Predicted from orthologs O54943
ZT 13 ZT 1 LD 2.5 hippocampus Predicted from orthologs O54943
ZT 16 ZT 0 LD 25 jejunum Predicted from orthologs O54943
ZT 15 ZT 23 LD 6 kidney Predicted from orthologs O54943
CT 15 CT 3 DD1 4 liver Predicted from orthologs O54943
ZT 16 ZT 4 LD 7 liver Predicted from orthologs O54943
CT 18 CT 6 DD2 10 MEFs Predicted from orthologs O54943
ZT 17 ZT 1 LD 6 megakaryocytes Predicted from orthologs O54943
ZT 18 ZT 6 LD 3 n primary visualcortex (V1) Predicted from orthologs O54943
CT 0 CT 12 DD2 10 NIH-3T3 cells Predicted from orthologs O54943
CT 12 CT 0 DD3 4.79 ovary Predicted from orthologs O54943
ZT 12 ZT 4 LD 5 pituitary gland Predicted from orthologs O54943
CT 12 CT 20 DD3 5 retina Predicted from orthologs O54943
ZT 12 ZT 16 LD 5 retina Predicted from orthologs O54943
CT 12 CT 20 DD3 6 retinal pigment epithelium)圧PE) Predicted from orthologs O54943
ZT 0 ZT 16 LD 2 retinal pigment epithelium)圧PE) Predicted from orthologs O54943
CT 9 CT 21 DD1 6 SCN Predicted from orthologs O54943
CT 8 CT 16 DD1 20 SCN Predicted from orthologs O54943
CT 15 CT 3 DD1 3 skeletal muscle Predicted from orthologs O54943
CT 14 CT 2 DD3 12 suprachiasmatic nucleus (SCN) Predicted from orthologs O54943
ZT 16 ZT 4 LD 9 abdominal adipose tissue Predicted from orthologs Q9Z301
ZT 16 ZT 4 LD 2 anterior cingulate Predicted from orthologs Q9Z301
ZT 14 ZT 2 LD 2.05 area postrema Predicted from orthologs Q9Z301
ZT 18 ZT 2 LD 6.38 AV3V Predicted from orthologs Q9Z301
ZT 16 ZT 4 LD 14 basolateral nucleus of the amygdala Predicted from orthologs Q9Z301
ZT 10 ZT 6 LD 2 caudal ventrolateral medulla Predicted from orthologs Q9Z301
CT 12 CT 8 DD17 4.35 colon Predicted from orthologs Q9Z301
ZT 14 ZT 2 LD 3.29 dorsal vagal motor nucleus Predicted from orthologs Q9Z301
ZT 2 ZT 14 LD 1.8 dorsomedial nucleus Predicted from orthologs Q9Z301
ZT 4 ZT 16 LD 5.5 entral nucleus of the amygdala Predicted from orthologs Q9Z301
ZT 14 ZT 2 LD 5.7 heart Predicted from orthologs Q9Z301
ZT 4 ZT 16 LD 15 hippocampus Predicted from orthologs Q9Z301
ZT 16 ZT 3 LD 57 intestinal jejunal mucosa Predicted from orthologs Q9Z301
CT 16 CT 4 DD17 5 liver Predicted from orthologs Q9Z301
ZT 14 ZT 2 LD 8.5 liver Predicted from orthologs Q9Z301
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q9Z301
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q9Z301
ZT 0 ZT 12 LD 7 nucleus accumbens shell Predicted from orthologs Q9Z301
ZT 14 ZT 6 LD 2.07 nucleus ambiguus Predicted from orthologs Q9Z301
ZT 14 ZT 6 LD 2.63 paraventricular nucleus Predicted from orthologs Q9Z301
ZT 8 ZT 20 LD 4 prefrontal cortex Predicted from orthologs Q9Z301
ZT 12 ZT 8 LD 2.5 PVN Predicted from orthologs Q9Z301
ZT 16 ZT 4 LD 2 rostral agranular insula Predicted from orthologs Q9Z301
ZT 12 ZT 20 LD 3.92 SCN Predicted from orthologs Q9Z301
ZT 8 ZT 20 LD 2 SCN Predicted from orthologs Q9Z301
ZT 12 ZT 20 LD 2 SCN Predicted from orthologs Q9Z301
Descriptionperiod circadian clock 2 [Source:HGNC Symbol;Acc:HGNC:8846](View all)
Protein Sequence
(Fasta)		 MNRYTEFPCS PSNLTKEPME AKPSQAPPLQ DDVDMSGGSS GNEATENCST GRDSQGSDCD 60
DSGKELGMLV EPPDVHQSPN AFSLMMATSE HNPSTSGCSS DQSAKANTHK ELIKTLKELK 120
VHLPADKKAK GKASTLATLK YALKSVKQVK ANEEYYQLLM SSESQPCGVD VPCYTVGEME 180
SMTSEYIGKN VDMFAVAVSL VTGKILYISD QVASIFHCKR DAFSDAKFVE FLAPHDVSVF 240
HSFTTPCKLP SWSVCGRADS FTQECMEEKS FFCRVSVGKN HENEIRYHPF RMTPYLAKVW 300
DQQGGERQFC CLLLAERVHS GYEAPRIPPE KRIFTTTHTP NCLFQDIDER AVPLLGYLPQ 360
DLIETPVLLQ LHPSDRPLML AVHKKILQSG GQPFDYSPIR FRAQNGEYIT LDTSWSSFIN 420
PWSRKISFII GRHKVRVGPL NEDVFAAHPC TEEKAPSPSI QELTEQIHRL LLQPVPHSGS 480
SGYGSLGSNG SHEHLMSQTS SSDSNGHEDS HQRRAETCKS GNRTKTKSHH SPEPGEQKKK 540
SSSEVPSSPS AQMKAVPAAK KDSSGASFSK ASMPEDLACR TQPTCSYQQI SCLDSVIRYL 600
ESCSEAATLK RKCEFPANIP TLRSSDKRKA VISPMPTGVL SYKEAVLPSK ANGHTEVRTH 660
LTSLALPSKA ESVVSLTSQC SYSSTIVHVG DKKPQPELEM VEDSVSGPES LDCLVGPSLP 720
CGLNQEKEPF KKLGLTKEVL AAHTQKEEQS FLQKFKEIRK LNIFQSHCHY YLQERSKGQL 780
SERTASGLRN TSGIDSSWKK TGKNRKLKSK RVKPRDSSDS TGSGGPVLHR PPLLGLNATA 840
WSPSDTSQAS CPTVPCPAPV PTFSLPVFPT AGTLAAPPAA PHASFTVPTV PMDAQNQFAV 900
QSPPFPTPLA PVVAFVLPSY SFPPGPPSLP QAFFPGHPHF PSHPMLVTEM TSPSQPKFPG 960
QTSTPRQPCT CPATPATPAT PPSAVGRASP PLFQSRGSSP LQLNLLQLEE TPEGGTGTAG 1020
TVGATGIAAA GLDCKPGTSR DRQPKASPTH HESSEAQNSD ALSTSSDLLN LLLNEDLCSA 1080
SGSALSGSAA SATSDSLGSS SLGGNASHSA AGSSDTSHTS KYFGSIDSSE NNHRAKLNAG 1140
MEGSEHLLKC VLQDPIWLLM ADTDDSVMMT YQLPARNLET VLKEDREKLK LLQKFQPRFT 1200
ESQKQELSEV HPWMRVGSLP TALDVAECVY CENKEKGSIC VTYEEDIPSL GQSEVSDTKE 1260
VENGPPLSHK NEEQT 1275
Nucleotide Sequence
(Fasta)		 ATGAATAGAT ACACGGAGTT TCCCTGCAGC CCCAGTAACC TCACCAAGGA GCCCATGGAG 60
GCCAAGCCCA GCCAGGCCCC CCCGCTCCAG GATGATGTGG ACATGAGCGG TGGCTCCAGC 120
GGAAATGAGG CCACTGAGAA CTGCTCCACG GGGCGGGACT CACAGGGCAG TGACTGTGAC 180
GACAGCGGGA AGGAGCTGGG GATGCTGGTG GAGCCACCGG ACGTCCACCA GAGTCCAAAT 240
GCCTTTAGCC TGATGATGGC CACGTCTGAA CACAACCCCT CTACGAGTGG CTGCAGTAGT 300
GACCAGTCTG CCAAAGCAAA CACACACAAA GAATTGATAA AAACACTGAA GGAGCTGAAG 360
GTCCACCTCC CCGCAGATAA GAAGGCCAAG GGGAAGGCCA GCACACTGGC AACTCTGAAG 420
TATGCCCTGA AGAGTGTGAA GCAAGTGAAA GCTAATGAAG AGTATTACCA GCTGCTGATG 480
TCCAGTGAGA GCCAGCCCTG TGGAGTGGAT GTGCCCTGCT ACACTGTGGG GGAGATGGAG 540
AGCATGACCT CCGAGTACAT CGGGAAGAAC GTGGATATGT TTGCAGTGGC TGTGTCCCTG 600
GTGACTGGGA AAATCCTGTA CATCTCTGAC CAAGTCGCAT CCATATTTCA CTGTAAAAGA 660
GACGCCTTCA GTGACGCCAA GTTCGTGGAG TTCCTGGCGC CTCACGATGT CAGTGTGTTC 720
CATAGCTTCA CCACACCTTG CAAGCTGCCC TCGTGGAGTG TGTGTGGCAG GGCAGATTCT 780
TTTACTCAAG AGTGCATGGA GGAGAAATCT TTCTTTTGCC GTGTCAGTGT CGGGAAGAAC 840
CACGAGAACG AGATTCGCTA CCACCCGTTC CGCATGACGC CCTACCTGGC TAAGGTGTGG 900
GACCAGCAGG GTGGGGAGAG ACAGTTCTGC TGCCTCCTGC TGGCAGAGCG CGTGCACTCA 960
GGCTATGAAG CTCCTAGAAT TCCTCCTGAA AAGAGAATTT TTACAACCAC CCACACACCA 1020
AATTGTTTGT TCCAGGACAT AGATGAAAGG GCAGTCCCCC TGCTGGGCTA CCTACCTCAG 1080
GACCTGATTG AGACCCCTGT GCTCCTGCAG CTTCACCCCA GCGACAGGCC CTTGATGCTG 1140
GCTGTCCACA AAAAGATCCT GCAGTCCGGT GGGCAGCCTT TTGATTATTC CCCCATCCGC 1200
TTCCGGGCTC AGAATGGGGA GTACATCACA CTGGACACCA GCTGGTCCAG CTTCATCAAC 1260
CCCTGGAGCA GGAAAATCTC CTTCATCATC GGGAGACATA AAGTCAGGGT GGGCCCTTTG 1320
AATGAGGACG TGTTCGCAGC ACACCCATGC ACAGAAGAAA AGGCCCCAAG TCCCAGCATT 1380
CAGGAGCTCA CGGAGCAGAT CCACCGGCTG CTGCTGCAGC CTGTCCCCCA CAGCGGTTCC 1440
AGTGGCTACG GGAGTCTGGG CAGCAACGGG TCTCACGAGC ACCTCATGAG CCAGACGTCC 1500
TCCAGCGACA GCAACGGCCA TGAGGACTCT CACCAGAGAA GAGCCGAAAC TTGTAAAAGT 1560
GGTAACAGGA CCAAAACGAA AAGTCATCAT TCTCCTGAAC CTGGAGAACA AAAGAAAAAG 1620
TCCAGTTCAG AAGTGCCAAG TAGTCCCTCA GCTCAGATGA AAGCTGTACC TGCTGCAAAG 1680
AAGGACAGCT CAGGAGCCAG CTTCTCCAAG GCCAGCATGC CAGAGGACCT GGCCTGCAGG 1740
ACCCAGCCCA CCTGCTCCTA CCAGCAGATC AGCTGCTTGG ACAGCGTCAT CAGGTACTTG 1800
GAGAGCTGCA GCGAGGCCGC CACTCTGAAG CGGAAGTGTG AGTTCCCAGC CAACATCCCC 1860
ACACTGAGGT CCAGCGACAA GCGGAAGGCC GTAATCAGCC CCATGCCCAC CGGAGTCTTG 1920
TCTTATAAAG AGGCAGTATT GCCCTCCAAA GCAAACGGCC ACACGGAGGT CAGAACTCAC 1980
CTCACCTCGC TGGCTCTGCC CAGCAAGGCT GAGAGCGTGG TGTCCCTCAC CAGCCAGTGC 2040
AGCTACAGCA GCACCATCGT CCACGTGGGG GACAAAAAAC CCCAGCCGGA GTTAGAGATG 2100
GTGGAAGATT CTGTGAGCGG TCCTGAGTCC CTGGACTGCC TGGTGGGCCC TTCCCTGCCT 2160
TGTGGCCTCA ACCAGGAGAA GGAGCCCTTT AAGAAGCTTG GCCTCACCAA GGAAGTGCTC 2220
GCTGCGCATA CCCAGAAGGA GGAGCAGAGC TTCCTGCAAA AGTTCAAGGA AATAAGAAAA 2280
CTCAATATTT TCCAATCTCA CTGCCATTAT TACTTACAAG AAAGATCCAA GGGGCAGTTG 2340
AGTGAACGAA CTGCCTCTGG ACTAAGAAAC ACTTCTGGAA TAGATTCATC TTGGAAAAAA 2400
ACTGGAAAAA ACAGAAAACT AAAGTCCAAA CGAGTCAAGC CTCGAGACTC CTCTGACAGC 2460
ACCGGGTCGG GGGGTCCTGT GCTCCACCGA CCCCCACTCT TAGGCCTGAA TGCCACTGCC 2520
TGGTCACCTT CAGACACATC CCAGGCCAGC TGCCCCACTG TGCCCTGTCC TGCTCCAGTG 2580
CCCACTTTCT CCCTGCCCGT GTTTCCAACA GCAGGGACTC TGGCGGCCCC GCCTGCAGCT 2640
CCTCACGCCA GCTTCACAGT GCCCACTGTG CCCATGGACG CCCAGAACCA GTTTGCAGTC 2700
CAGTCCCCAC CCTTCCCCAC ACCCTTAGCC CCTGTTGTGG CTTTCGTGCT ACCCAGCTAC 2760
TCCTTCCCCC CGGGTCCCCC AAGCCTGCCA CAGGCCTTCT TCCCCGGCCA CCCTCACTTC 2820
CCCAGCCATC CCATGCTTGT GACCGAGATG ACCTCTCCCT CACAGCCCAA GTTCCCAGGC 2880
CAGACCTCTA CCCCTAGACA GCCATGTACT TGTCCAGCAA CCCCAGCCAC CCCAGCCACC 2940
CCACCATCAG CTGTAGGCCG GGCCTCCCCG CCACTCTTCC AGTCCCGTGG CAGCTCGCCC 3000
CTGCAACTCA ACCTCCTGCA GTTAGAGGAG ACCCCTGAGG GTGGCACTGG GACTGCGGGG 3060
ACAGTGGGAG CCACAGGGAT AGCAGCTGCG GGGCTGGACT GCAAACCTGG CACCTCTCGG 3120
GACCGACAGC CAAAGGCTTC TCCAACTCAT CACGAGTCCT CAGAGGCCCA GAATAGTGAC 3180
GCCCTCTCCA CGTCCAGTGA CCTGCTGAAC CTCCTATTGA ATGAAGACCT CTGCTCAGCC 3240
TCAGGCTCAG CCCTGTCTGG GAGCGCAGCC TCCGCCACCT CGGACTCGCT GGGCTCCAGC 3300
TCACTGGGCG GCAATGCTTC CCACAGCGCG GCAGGCAGTA GTGACACAAG TCACACCAGC 3360
AAATATTTTG GAAGCATTGA CTCTTCAGAG AATAATCACA GAGCAAAGCT GAATGCAGGC 3420
ATGGAAGGCA GTGAGCACCT CCTCAAGTGT GTCCTGCAGG ACCCCATCTG GCTGTTGATG 3480
GCCGATACGG ACGACAGCGT CATGATGACG TACCAGCTGC CAGCCCGAAA TTTAGAAACA 3540
GTTTTGAAGG AGGACAGAGA GAAGCTGAAA CTACTGCAGA AGTTCCAGCC CCGGTTCACG 3600
GAGAGTCAGA AGCAGGAGCT GAGCGAGGTC CACCCGTGGA TGCGTGTGGG CAGCCTGCCC 3660
ACGGCCCTGG ACGTGGCGGA ATGTGTTTAT TGTGAAAACA AGGAAAAAGG CAGCATTTGT 3720
GTGACATATG AAGAAGATAT CCCTTCTCTG GGACAAAGCG AAGTTTCAGA CACCAAAGAA 3780
GTGGAAAATG GACCCCCCTT GAGTCACAAG AATGAGGAAC AGACATAA 3828
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans24.54 2.70e-17 88.58
CGD-EqC-020992Equus caballus68.27 0.00e+00 1616.3
CGD-GaG-021834Gallus gallus52.57 0.00e+00 1226.5
CGD-HoS-021036Homo sapiens (Human)73.9 0.00e+00 1847.4
CGD-MuM-021066Mus musculus (Mouse)65.83 0.00e+00 1624.8
CGD-RaN-022186Rattus norvegicus64.74 0.00e+00 1600.5
Gene Ontology

GO:0005515--protein binding
GO:0004871--signal transducer activity
GO:0007165--signal transduction
GO:0005654--nucleoplasm
GO:0005634--nucleus
GO:0005737--cytoplasm