CGDB Gene Information

Tag Content
CGDB ID CGD-MaM-031836
Ensembl Accession ENSMMUP00000028711.2
Protein Name PER1
Ensembl Information ENSMMUG00000021798; ENSMMUT00000030676
Organism Macaca mulatta
NCBI Taxa ID 9544
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSGPLEGADG GGDPRPGESF CPGGVPSPGP PQHRPCPGPS LADDTDANSN GSSGNESNGH 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCSMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGR IVYISEQAAV 240
LLRCKRDVFR GTRFSELLAP QDVGVFYGST APSRLPTWGT GASAGSGLRD FTQEKSVFCR 300
IRGGPDRDPG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAP 480
TLDTDIQELS EQIHRLLLQP VHSPSPTGLC GVGPVTSPGP LHSPGSSSDS NGGDAEGPGP 540
PAPVTFQQIC KDVHLVKHQG QQLFIESRAR PQPRPRLPAT GTFKARALPC QSPDPELETG 600
SAPIPAPLAL APEEAERKEA SSCSYQQINC LDSILRYLES CNLPSTTKRK CASSSSYTTS 660
SASDDDKQRT GPVPVGTKKD PPSAVLSGEG ATPRKEPVVG GTLSPLALAN KAESVVSVTS 720
QCSFSSTIVH VGDKKPPESD IIMMEDLPGL APGPAPSPAP SPTVAPDPAP DAYRPVGLTK 780
AVLSLHTQKE EQAFLSRFRD LGRLRGLDSS STAPSALGER GCHHGPAPLS RRHHCRSKAK 840
RSRHHQSPRA EAPCYVSHPS PVPPSTPWPA PPATTPFPAV VQPYPLPVFS PRGGPQPLPP 900
APTSVPPAAF PTPLVTPMVA LVLPNYLFPT PSSYPYGAPQ TPAEGPPTPA SYSPSPSLPA 960
LPPSPPRRPD SPLFNSRCSS PLQLNLLQLE ELPRAEGAAG AGGPGSSAGP PPPSEEAAEP 1020
EARLVEVTES SNQVSLSGSS DLLELLLQDE SRSGTGSAAS GSLGSGLGSG SGSGSHEGGS 1080
TSASITRDSQ SSHTSKYFGS IDSSEAEAGA ARGGAEPGDQ VIKYVLQDPI WLLMANADQR 1140
VMMTYQVPSR DMTSVLKQDR ERLRAMQRQQ PRFSEDQRRE LGAVHSWVRK GQLPRALDVM 1200
ACVDCGSSTQ DPGHPDDPLF SELDGLGLEP MEEGGGEQGS SGGGSGEGEG CEEARAQGGA 1260
KASSSQDLAM EEEKESRSSA SPALPTAGNG TS 1292
Nucleotide Sequence
(Fasta)		 GGCTGGAGCA GCGGCGGGCA GGCGGGCCGA GGACACTCCC GCGACCAGGT ACTGGCTGTG 60
CTCGAACTTG TCAACCCTCA GAGACTTAAA TCTTCCACCT CACTCCCTCA GCCAGGCCTC 120
CAGGCCCCCC CGTGCATCCG TGGTGGCCTC TTCGCCTTCT CTGTTCTGTT CTCCCCATGG 180
CCCAGACATG AGTGGCCCCC TAGAAGGGGC TGATGGGGGA GGGGACCCCA GGCCTGGGGA 240
ATCATTTTGT CCTGGGGGGG TCCCATCCCC TGGGCCCCCA CAGCACCGGC CTTGCCCAGG 300
CCCCAGCCTG GCCGATGACA CCGATGCCAA CAGCAATGGT TCAAGTGGCA ATGAGTCCAA 360
CGGGCATGAG TCCAGGGGCG CATCTCAGCG GAGCTCACAC AGCTCCTCCT CAGGCAATGG 420
CAAGGACTCA GCCCTGTTGG AGACCACTGA GAGCAGCAAG AGCACAAACT CTCAGAGCCC 480
ATCCCCACCT AGCAGTTCCA TTGCCTACAG CCTCCTGAGT GCCAGCTCAG AGCAGGACAA 540
CCCGTCCACC AGTGGCTGCA GCAGTGAACA GTCAGCCCGG GCGAGGACCC AGAAGGAACT 600
CATGACAGCA CTTCGAGAGC TCAAGCTTCG ACTGCCACCA GAGCGCCGGG GCAAGGGCCG 660
CTCTGGGACC CTGGCCACGC TGCAGTACGC GCTGGCCTGT GTCAAGCAAG TGCAGGCCAA 720
CCAGGAATAC TACCAGCAGT GGAGCCTGGA GGAGGGCGAG CCTTGCTCCA TGGACATGTC 780
CACCTATACC CTGGAGGAGC TGGAGCACAT CACGTCTGAG TACACGCTTC GTAACCAGGA 840
TACCTTCTCA GTGGCTGTCT CCTTCCTGAC GGGCCGAATC GTCTACATTT CGGAGCAGGC 900
AGCTGTCCTG CTGCGTTGCA AGCGGGACGT GTTCCGGGGT ACCCGCTTCT CCGAGCTCCT 960
GGCTCCCCAG GATGTGGGAG TCTTCTATGG TTCCACTGCT CCATCTCGCC TGCCCACCTG 1020
GGGCACAGGG GCCTCAGCAG GTTCAGGCCT CAGGGACTTT ACCCAGGAGA AGTCTGTCTT 1080
CTGCCGTATC AGAGGAGGTC CTGACCGGGA TCCAGGGCCT CGGTACCAGC CATTCCGCCT 1140
AACCCCGTAT GTGACCAAGA TCCGGGTCTC AGATGGGGCC CCTGCGCAGC CGTGCTGCCT 1200
GCTGATTGCA GAGCGCATCC ACTCGGGTTA CGAAGCTCCC CGGATACCCC CTGACAAGAG 1260
GATTTTCACT ACACGGCACA CGCCCAGCTG CCTCTTCCAG GATGTGGATG AAAGGGCTGC 1320
CCCCCTGCTG GGCTACCTGC CCCAGGACCT CCTGGGGGCC CCAGTGCTCC TGTTCCTGCA 1380
CCCTGAGGAC CGACCCCTCA TGCTGGCTAT CCACAAGAAG ATCCTGCAGT TGGCGGGCCA 1440
GCCCTTTGAC CACTCCCCCA TCCGCTTCTG TGCCCGCAAC GGGGAGTATG TCACCATGGA 1500
CACCAGTTGG GCTGGCTTTG TGCATCCCTG GAGCCGCAAG GTAGCCTTCG TGTTGGGCCG 1560
CCACAAAGTA CGCACGGCCC CGCTGAATGA GGATGTGTTC ACTCCCCCGG CCCCCAGCCC 1620
AGCTCCGACC CTGGACACTG ATATCCAGGA GCTGTCAGAG CAGATCCACC GGCTGCTGCT 1680
ACAGCCTGTG CACAGCCCCA GCCCCACAGG ACTCTGTGGA GTCGGCCCCG TGACATCTCC 1740
AGGCCCTCTC CACAGCCCCG GCTCCTCCAG TGATAGCAAC GGGGGTGATG CAGAGGGGCC 1800
TGGGCCTCCT GCGCCAGTGA CTTTCCAGCA GATCTGTAAG GATGTGCATC TGGTGAAGCA 1860
CCAGGGCCAG CAGCTTTTTA TTGAGTCTCG GGCCCGGCCT CAGCCCCGGC CTCGCCTCCC 1920
TGCTACAGGC ACATTCAAGG CCAGGGCCCT TCCCTGCCAA TCCCCAGACC CAGAGCTGGA 1980
GACGGGTTCT GCTCCCATCC CGGCCCCACT AGCCTTGGCC CCTGAGGAGG CCGAGAGGAA 2040
AGAAGCCTCC AGCTGCTCCT ACCAACAGAT CAACTGCCTG GACAGCATCC TCAGGTATCT 2100
GGAGAGCTGC AACCTCCCCA GCACCACTAA GCGTAAATGT GCCTCCTCCT CCTCTTACAC 2160
CACCTCCTCA GCCTCTGACG ATGACAAGCA GAGGACTGGT CCAGTCCCTG TGGGGACCAA 2220
GAAAGATCCG CCGTCAGCAG TGCTGTCTGG GGAGGGGGCC ACCCCCCGGA AGGAGCCAGT 2280
GGTGGGAGGC ACCTTGAGCC CGCTCGCCCT GGCCAATAAG GCGGAGAGCG TGGTGTCCGT 2340
CACCAGTCAG TGTAGCTTCA GCTCCACCAT CGTCCATGTG GGAGACAAGA AGCCCCCGGA 2400
GTCGGACATC ATCATGATGG AGGACCTGCC TGGCCTAGCC CCCGGCCCAG CCCCCAGCCC 2460
AGCCCCCAGC CCCACAGTAG CCCCTGACCC AGCCCCAGAT GCCTACCGTC CAGTAGGGCT 2520
GACCAAGGCC GTGCTGTCCC TGCACACACA GAAGGAAGAG CAAGCCTTCC TCAGCCGCTT 2580
CCGAGACCTG GGCAGGCTGC GTGGACTCGA CAGCTCTTCC ACAGCGCCCT CAGCCCTTGG 2640
CGAGCGAGGC TGCCACCACG GCCCCGCACC CCTAAGCCGC CGACACCACT GCCGATCCAA 2700
AGCCAAGCGC TCACGCCACC ACCAGAGCCC TCGGGCTGAA GCGCCCTGCT ACGTCTCACA 2760
CCCCTCACCT GTGCCACCCT CCACCCCCTG GCCTGCCCCA CCAGCCACTA CCCCCTTCCC 2820
AGCAGTTGTC CAGCCCTACC CTCTCCCAGT GTTCTCCCCT CGAGGAGGCC CCCAGCCTCT 2880
TCCCCCTGCT CCCACATCTG TGCCCCCGGC TGCTTTCCCC ACCCCTCTGG TGACCCCCAT 2940
GGTGGCCTTG GTGCTCCCTA ACTATCTGTT CCCAACCCCA TCCAGCTATC CTTACGGGGC 3000
ACCCCAGACC CCTGCTGAAG GGCCTCCCAC TCCTGCCTCG TACTCCCCTT CTCCATCCTT 3060
GCCCGCCCTC CCCCCAAGCC CTCCTCGCCG CCCGGACTCT CCACTGTTCA ACTCAAGATG 3120
CAGCTCTCCA CTCCAGCTTA ATCTGCTGCA GCTCGAGGAG CTCCCCCGTG CTGAGGGGGC 3180
TGCTGGTGCA GGGGGCCCTG GGAGCAGTGC TGGGCCCCCA CCTCCCAGTG AGGAGGCTGC 3240
TGAGCCAGAG GCCAGACTGG TGGAGGTCAC TGAGTCCTCC AATCAGGTCT CACTGTCCGG 3300
CTCCAGCGAC CTGCTGGAAC TGCTGCTGCA AGATGAGTCG CGCTCCGGCA CAGGCTCCGC 3360
AGCCTCGGGC TCCTTGGGCT CTGGCTTGGG CTCTGGGTCT GGTTCAGGCT CCCATGAGGG 3420
GGGCAGCACC TCAGCCAGCA TCACTCGTGA CAGCCAGAGC AGCCACACAA GCAAATACTT 3480
TGGCAGCATC GACTCTTCCG AGGCTGAGGC TGGGGCTGCT CGGGGCGGGG CTGAGCCGGG 3540
GGACCAGGTG ATTAAGTACG TGCTCCAGGA TCCCATTTGG CTGCTCATGG CCAATGCTGA 3600
CCAGCGCGTC ATGATGACTT ACCAGGTACC CTCCAGGGAC ATGACCTCTG TGCTGAAGCA 3660
GGATCGGGAG CGGCTCCGAG CCATGCAGAG GCAGCAGCCC CGGTTTTCTG AGGACCAGCG 3720
GCGGGAACTG GGCGCTGTGC ACTCCTGGGT CCGCAAGGGC CAACTGCCTC GGGCTCTTGA 3780
TGTGATGGCC TGTGTGGACT GTGGGAGCAG CACCCAAGAT CCTGGTCACC CTGATGACCC 3840
ACTCTTCTCA GAGCTGGATG GACTGGGGCT GGAGCCCATG GAAGAGGGTG GAGGCGAGCA 3900
GGGCAGCAGC GGTGGCGGCA GTGGTGAGGG TGAGGGCTGC GAGGAGGCCA GGGCCCAAGG 3960
TGGGGCCAAG GCCTCAAGCT CTCAGGACTT GGCCATGGAG GAGGAGAAAG AAAGCAGGAG 4020
CTCAGCCAGT CCAGCCTTAC CTACAGCAGG AAACGGCACG AGCTAGACTC CATTCTGGGA 4080
CCATCTCCAG GAGTCCACAA GATGCTTTCT TCTCCTATGT CCCAATTCTC AGAACTCAGA 4140
TGTGGCTGGA CCAACCAGTG GGAAACTGCC CCAGCTTCTC CCACCATAGG GGGCCGGACC 4200
CCCATCACCA GCCCAGGATC CAGGGGCTGC CTCTGACCTC GTAGGGAGCA GAGAGCAGAA 4260
CTCCGCAGCC CAGCCCAGCC CAGAGGAGTG TCACCTCCCA CCTTTGGAGA GGAATCCTTC 4320
CCTCCCCTGG ACAGAGTTGC TGACAGGCTG CTTAAGTGGC CTCTCCATAT CCTAGCTGAG 4380
CCTGAATCCG ACTCCTGAGG GTTGGGGCTG CACTTATTTA TCGGGGGAGA CAGCTGTCTC 4440
TCCCACCTCC TCCCCACATG GGAGGAGAGC CTGAGGCCCA AGCAGGACCT GGGGGATCCA 4500
GCCCCTAGCT GCTCGGGGGT GGGGGAGGTT GGTGGACCAT GGAGTCCCTG GTGCTGCCCC 4560
TCAGGTGGGA CCCAGGTGTT CTCAGCTGTA CCCTCTGCCG ATGGCATTTG TGTTTTTGAT 4620
ATTTGTGTCT GTTACTACTT TTTTAAT 4647
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans27.17 2.10e-14 78.95
CGD-EqC-020994Equus caballus62.21 0.00e+00 1478.8
CGD-GaM-021007Gadus morhua54.28 5.00e-176 615.5
CGD-HoS-021038Homo sapiens (Human)65.63 0.00e+00 1587.4
CGD-OvA-022197Ovis aries61.13 0.00e+00 1446.4
CGD-RaN-021793Rattus norvegicus63.55 0.00e+00 1459.9
Gene Ontology

GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0005515--protein binding
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation