CGDB Gene Information

Tag Content
CGDB ID CGD-ErE-072203
Ensembl Accession ENSEEUP00000008506.1
Protein Name PER1
Ensembl Information ENSEEUG00000009292; ENSEEUT00000009330
Organism Erinaceus europaeus
NCBI Taxa ID 9365
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 21 ZT 9 LD 6 duodenum Predicted from orthologs Q8QGQ8
ZT 2 ZT 18 LD 3.17 embryos Predicted from orthologs Q8QGQ8
ZT 6 ZT 18 LD 8 embryos Predicted from orthologs Q8QGQ8
CT 12 CT 0 DD1 3 granulosa cells Predicted from orthologs Q8QGQ8
ZT 3 ZT 18 LD 84.29 pineal glands Predicted from orthologs Q8QGQ8
ZT 23 ZT 11 LD 2.25 spleen Predicted from orthologs Q8QGQ8
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSSSLEGDGG GDPRPGESFG PGGTPPPGPP QHRPCPDPSL ADDTDANSNG SSGNESNGPE 60
SRGASQRSSH SSSSGNGKDS ALLETTESSK STNSQSPSPP SSSIAYSLLS ASSEQDNPST 120
SGCSSEQSAR ARTQKELMTA LRELKLRLPP ERRGKGRSGT LATLQYALAC VKQVQANQEY 180
YQQWSLEEGE SCAMDMSTYT LEELEHITSE YTLRNQDTFS VAVSFLTGRI IYISEQAGIL 240
LRCKRDVFRG ARFSELLAPQ DVGVFYGSTA PSRLPTWGAG AAAGSGLKDF TQEKSVFCRI 300
RGGPDRDPGP WYQPFRLTPY VTKIRVTDGA PAQPCCLLIA ERVHSGYEAP RIPPDKRIFT 360
TRHTPSCLFQ DVDERAAPLL GYLPQDLLGA PVLLFLHPED RPLMLAIHKK ILQLAGQPFD 420
HSPIRFCARN GEYVTMDTSW AGFVHPWSRK VAFVLGRHKV RTGPLXXXXX XXXXXXXXXX 480
XXXXXXXXXX XXXXXXXXXX HSPSPTGLCG VGTVTSPAPL LSPGSSSDSN GGDTEGPGPP 540
APVTFQQICK DVHLVKHQGQ QVFIESRTRP PARPRLPATG TFKAKTFACQ PPAPELDIAP 600
APVQVSLALA PEESEKKETP TSSYQQINCL DSILRYLESC NIPSTTKRKC ASSSSCTTSS 660
ASDDDKQRTG PVPVEAKKDP SSAVLSGEGA TPRKEPVVGG TLSPLALANK AESVVSVTSQ 720
CSFSSTIVHV GDKKPPESDI IMMEDLPGLA PGPAPSPAPS PIVAPDPAPD AYRPVGLTKA 780
VLSLHTQKEE QAFLSRFRDL GRLRGLDGSS TAPLAPGEQG CHHGPTPHGR RHHCRSKAKR 840
SRHHQTPRTE APCYVNHPSP VPPSAPWPPP PTTTPFPAVV QPYPLPVFSP RAGAQTLPPA 900
PTSVSPAAFP APLVTPMVAL VLPNYLFPTP TSYPYDVPQV PAEGPPTPAS HSPSPSLLPL 960
PPSPPNRPDS PLFNSRCSSP LQLNLLQLEE LPRAEGSAVI GGPGSSVGPP PPSEEAAEPE 1020
ARLVEVTESS NQDALSGSSD LLELLLQEDS RSGTGSAASG SLGSGMGSGS GSGSHEGGST 1080
SASITRDSQS SHTSKYFGSI DSSEAETGAA QVRAEPGDQV IKYVLQDPIW LLMANADQHV 1140
MMTYQVPSRD VASVLKQDRE RLRAMQKQQP RFSEDQQREL GAVHSWVRKG QLPRALDVMA 1200
CVDCGSSSQD PSHPSDPLFS ELDGLGLEPM EEGGGDGGGP GGEGAGGDET QVQADARVSS 1260
SQDLAMEEEE QGGSSSGPAL PATENGTS 1288
Nucleotide Sequence
(Fasta)		 ATGAGTAGCT CCCTAGAAGG GGATGGGGGA GGGGACCCCA GACCTGGGGA ATCCTTTGGT 60
CCTGGAGGAA CCCCACCCCC TGGCCCTCCA CAGCATCGGC CTTGCCCAGA CCCCAGTCTG 120
GCTGATGACA CTGATGCCAA CAGCAATGGC TCCAGCGGCA ATGAGTCCAA TGGGCCAGAG 180
TCCAGGGGTG CATCTCAGCG GAGCTCACAT AGTTCCTCCT CTGGCAATGG CAAGGACTCG 240
GCCCTGCTGG AGACAACTGA GAGCAGCAAG AGCACAAACT CTCAAAGCCC ATCCCCACCC 300
AGCAGTTCCA TTGCCTACAG CCTCCTGAGT GCCAGCTCAG AGCAGGACAA CCCATCTACC 360
AGCGGCTGCA GCAGTGAACA GTCAGCCCGG GCAAGGACCC AGAAGGAACT TATGACTGCA 420
TTGCGGGAGC TCAAGCTTCG ACTGCCACCA GAACGTCGGG GCAAGGGCCG CTCTGGGACC 480
CTGGCCACAC TACAGTACGC ACTGGCCTGT GTTAAGCAGG TGCAAGCCAA CCAGGAATAC 540
TACCAGCAGT GGAGCCTGGA GGAGGGGGAA TCTTGTGCAA TGGACATGTC TACCTATACT 600
TTGGAGGAAC TGGAGCACAT CACATCTGAG TACACCCTTC GCAACCAGGA CACCTTCTCC 660
GTGGCTGTCT CCTTCCTGAC AGGCCGCATC ATCTACATTT CGGAGCAGGC AGGTATCTTA 720
CTGCGCTGCA AGCGGGATGT GTTCCGAGGT GCCCGATTCT CAGAGCTGCT GGCTCCTCAG 780
GATGTGGGCG TCTTCTATGG TTCCACTGCC CCATCCCGTC TGCCCACCTG GGGTGCTGGG 840
GCCGCAGCAG GTTCAGGCCT CAAGGATTTC ACCCAGGAGA AGTCTGTTTT CTGCCGTATC 900
AGAGGAGGTC CTGACCGTGA CCCAGGGCCC TGGTACCAGC CATTCCGCTT AACCCCATAT 960
GTGACCAAGA TCCGGGTCAC AGATGGTGCC CCCGCACAGC CCTGCTGCCT GCTTATCGCA 1020
GAACGTGTCC ACTCGGGTTA TGAAGCTCCC CGGATCCCAC CTGATAAGAG GATCTTCACC 1080
ACACGGCACA CACCCAGCTG CCTCTTCCAG GACGTGGATG AAAGGGCCGC CCCACTGCTG 1140
GGCTATCTCC CCCAGGACCT CTTGGGGGCC CCAGTGCTCC TGTTTCTGCA TCCTGAGGAC 1200
CGCCCTCTCA TGCTGGCCAT CCACAAGAAG ATCCTGCAGC TGGCTGGTCA ACCTTTTGAC 1260
CACTCACCTA TCCGTTTCTG TGCTCGTAAT GGGGAGTATG TCACCATGGA CACCAGCTGG 1320
GCCGGCTTTG TGCACCCGTG GAGCCGCAAG GTAGCCTTTG TGTTGGGCCG CCACAAAGTA 1380
CGCACGGGAC CCCTGNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1440
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1500
CACAGCCCCA GCCCCACGGG GCTCTGTGGA GTAGGCACTG TGACTTCCCC AGCCCCTCTC 1560
CTCAGCCCTG GATCCTCCAG TGATAGCAAT GGGGGAGATA CAGAAGGACC AGGGCCTCCC 1620
GCCCCGGTGA CCTTCCAGCA AATCTGTAAG GATGTCCATC TGGTGAAGCA CCAGGGGCAG 1680
CAGGTCTTTA TTGAGTCCCG TACTAGGCCT CCAGCCCGGC CCCGCCTCCC TGCTACAGGC 1740
ACATTCAAGG CCAAGACCTT TGCCTGCCAG CCCCCAGCCC CAGAGCTGGA CATTGCCCCT 1800
GCTCCAGTCC AGGTTTCATT AGCCTTGGCT CCAGAGGAAT CTGAAAAGAA AGAGACCCCC 1860
ACCTCCTCCT ACCAGCAGAT CAACTGCCTT GACAGCATTC TTCGGTACCT GGAGAGCTGC 1920
AACATCCCCA GCACAACCAA GCGTAAATGT GCCTCCTCCT CCTCCTGCAC CACCTCCTCA 1980
GCCTCTGACG ATGACAAGCA GAGGACAGGT CCAGTTCCTG TGGAGGCCAA GAAAGATCCA 2040
TCGTCGGCAG TGCTGTCTGG GGAGGGGGCC ACCCCTCGGA AGGAGCCAGT GGTGGGAGGC 2100
ACCTTGAGCC CGCTCGCCCT GGCTAATAAG GCAGAGAGTG TGGTGTCCGT CACCAGTCAG 2160
TGTAGCTTCA GCTCCACCAT CGTCCATGTG GGAGACAAGA AGCCCCCGGA GTCGGACATC 2220
ATCATGATGG AAGATCTCCC TGGCCTGGCT CCAGGCCCAG CCCCCAGCCC AGCCCCCAGC 2280
CCCATCGTAG CTCCTGACCC AGCCCCAGAT GCCTACCGAC CGGTGGGTCT GACCAAGGCT 2340
GTGCTGTCCC TGCACACACA GAAGGAGGAG CAGGCCTTCC TCAGCCGCTT CCGTGACCTT 2400
GGCAGGCTGC GTGGACTGGA TGGCTCCTCC ACAGCCCCCT TGGCTCCTGG TGAGCAAGGC 2460
TGTCACCACG GCCCCACACC CCATGGCCGT CGACACCACT GCCGATCCAA AGCTAAGCGC 2520
TCACGCCACC ACCAGACCCC CCGGACTGAA GCCCCCTGCT ATGTCAATCA CCCCTCACCT 2580
GTGCCGCCCT CTGCCCCCTG GCCCCCACCA CCAACCACTA CCCCCTTCCC AGCTGTGGTC 2640
CAGCCATACC CCCTCCCAGT GTTCTCCCCC AGAGCAGGAG CCCAGACTCT TCCCCCTGCC 2700
CCCACATCAG TGTCCCCTGC AGCTTTCCCT GCCCCCTTAG TGACCCCAAT GGTAGCCTTG 2760
GTGCTCCCTA ACTATCTGTT CCCTACCCCA ACCAGCTATC CCTATGATGT ACCCCAGGTC 2820
CCTGCTGAGG GGCCTCCTAC CCCTGCCTCC CATTCTCCTT CTCCATCCCT GCTCCCCTTA 2880
CCCCCCAGCC CTCCCAACCG CCCAGACTCT CCACTGTTCA ACTCAAGATG CAGCTCCCCA 2940
CTCCAGCTGA ATCTGCTGCA GCTTGAGGAG CTTCCCCGAG CTGAGGGGAG TGCTGTTATA 3000
GGGGGCCCTG GGAGCAGTGT TGGGCCCCCA CCTCCCAGTG AGGAGGCTGC TGAGCCAGAG 3060
GCCAGACTGG TGGAGGTAAC TGAGTCCTCC AACCAGGATG CCCTTTCGGG CTCCAGTGAC 3120
CTGTTGGAGT TGCTGCTGCA AGAGGACTCT CGGTCTGGCA CCGGCTCTGC TGCCTCGGGC 3180
TCCTTGGGCT CTGGCATGGG CTCTGGGTCT GGTTCAGGCT CCCATGAAGG GGGCAGCACC 3240
TCTGCCAGTA TCACACGTGA CAGTCAAAGC AGCCACACAA GCAAGTACTT TGGCAGCATC 3300
GACTCTTCTG AAGCTGAGAC TGGTGCTGCC CAGGTTAGGG CTGAGCCCGG GGACCAGGTC 3360
ATTAAGTATG TGCTCCAGGA TCCCATCTGG CTGCTCATGG CCAATGCTGA CCAGCACGTC 3420
ATGATGACCT ACCAGGTGCC CTCCAGGGAT GTGGCCTCTG TGCTGAAGCA GGATCGGGAG 3480
AGGCTCCGTG CCATGCAGAA GCAGCAGCCT AGGTTCTCAG AGGATCAGCA GAGAGAGCTG 3540
GGGGCTGTGC ACTCCTGGGT TCGAAAGGGC CAGCTTCCAC GGGCCCTTGA TGTGATGGCC 3600
TGTGTGGACT GTGGAAGTAG CAGCCAAGAC CCCAGCCACC CCAGTGACCC ACTTTTCTCA 3660
GAACTGGATG GACTGGGGCT GGAGCCCATG GAGGAGGGTG GAGGGGATGG GGGTGGTCCT 3720
GGTGGTGAGG GTGCAGGTGG AGATGAGACC CAGGTCCAAG CTGACGCTAG GGTTTCAAGC 3780
TCTCAAGACT TAGCCATGGA GGAAGAGGAA CAAGGTGGGA GTTCGTCCGG TCCAGCCTTA 3840
CCTGCCACAG AAAACGGCAC CAGCTAA 3867
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans28.24 2.60e-12 72.02
CGD-EqC-020994Equus caballus63.61 0.00e+00 1372.8
CGD-GaG-021834Gallus gallus38.86 1.00e-158 557.4
CGD-HoS-021038Homo sapiens (Human)59.87 0.00e+00 1384
CGD-OvA-022197Ovis aries62.07 0.00e+00 1337
CGD-RaN-021793Rattus norvegicus62.35 0.00e+00 1366.7
Gene Ontology

GO:0004871--signal transducer activity
GO:0007165--signal transduction
GO:0005515--protein binding
GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation