CGDB Gene Information

Tag Content
CGDB ID CGD-LoA-069322
Ensembl Accession ENSLAFP00000010215.4
Protein Name PER1
Ensembl Information ENSLAFG00000012222; ENSLAFT00000012225
Organism Loxodonta africana
NCBI Taxa ID 9785
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSGPIEGAHG GGDPRPGDAF CPGGPPSLGP SQHRPCPGPS LADDTDANSN GSSGNESNGP 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMM ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCAMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGR IVYISEQAGI 240
LLRCKRDVFR GARFSELLAP QDVGVFYGST APSRLPTWGT GASAGSGPKD FTQEKSVFCR 300
ISGGPDRDSG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAL 480
SLDPDIQELS EQIHRLLLQP VHSPSPTGLC GVGPATSPGP LLSPGSSSDS NRGDTQGPGP 540
PGPVTFQQIC KDVHLVKHQG QQLFIESRVR PPPRPRLPAT GTFKAKALPC QSPELEVALA 600
PVHVPLGLAH EEGEKKEAST CSYQQINCLD SILRYLESCN IPNTTKRKCA SSSSCTTSSV 660
SDDDKQRAGP VPASVKKDPT AVLSGEGATP QKEPVVGGNL SPLALANKAE SVVSITSQCS 720
FSSTIVHVGD KKPPESDIVM MEDLPGLAPG PAPSPAPSST VAPDPAPDAY RPVGLTKAVL 780
SLHTQKEEQA FLSRFRDLGR LPGLDGSSPA PSAPGCHHGP VTPGRRHHCR SKAKRSRHQQ 840
IPRPGTPCYV SQPSPAPPSA PWPPPPATTP FSAVVQPYPL PVFSPRGGPQ PLPPAPTPVP 900
PAAFPAPLVT PVVALVLPNY LFPTPSSCPY GVPQAPAEGP PTPASHSPSP SLPPPPPSPP 960
HCPDSPLFNS RCSSPLQLNL LQLEEPPRAE GGAVAGPPGN SAGPPLPNEE ALEPEARLVE 1020
VTESSNQDML SGSSDLLELL LQEDSRSGTG SAASGSLGSG LGSGSGSGSH AGGSTSASVT 1080
RSSQSSHTSK YFGSIDSSEA EAGTAQAEAE PGDQVMKYVL QDPLWLLLAN ADQRVMMTYQ 1140
VPARDMASVL KQDRERLRVM QKQQPRFSED QRRELGAVHS WVRRGQLPRA LDVMACVDCG 1200
SSTQDPGHPD DPLFSELDVL GLEPMEEGGG EGVGGSEGGG GEGEGGGEAG AQAGAIVSSS 1260
QDLAMEEEEQ GGSSSSPALP APVNGTS 1287
Nucleotide Sequence
(Fasta)		 ATGAGCGGCC CCATAGAGGG GGCTCATGGG GGAGGGGACC CCAGGCCTGG AGATGCTTTT 60
TGTCCTGGAG GGCCCCCATC CCTGGGGCCC TCACAGCACC GGCCTTGCCC AGGCCCCAGT 120
CTGGCCGATG ACACGGATGC CAACAGCAAT GGCTCGAGTG GCAATGAATC CAATGGTCCT 180
GAGTCCAGGG GTGCATCTCA GCGGAGCTCA CATAGCTCCT CCTCCGGCAA CGGCAAGGAC 240
TCAGCCCTGC TGGAGACCAC TGAGAGCAGC AAGAGCACAA ACTCTCAGAG CCCATCCCCA 300
CCCAGCAGTT CCATTGCCTA CAGCCTCCTG AGTGCCAGCT CAGAGCAGGA CAACCCATCT 360
ACCAGTGGCT GCAGCAGTGA ACAGTCAGCT CGGGCGAGGA CCCAGAAGGA GCTCATGATG 420
GCGCTTCGGG AGCTCAAGCT TCGGCTGCCA CCAGAGCGCC GGGGCAAGGG TCGCTCTGGG 480
ACCCTGGCTA CACTTCAGTA CGCACTGGCT TGCGTCAAGC AGGTGCAGGC CAACCAGGAA 540
TACTACCAGC AGTGGAGCCT GGAGGAGGGT GAGCCCTGTG CCATGGACAT GTCCACCTAC 600
ACTCTGGAGG AGCTGGAACA TATCACATCT GAGTACACGC TTCGTAACCA GGACACCTTC 660
TCGGTGGCTG TCTCTTTCCT GACAGGCCGC ATTGTCTACA TTTCGGAGCA GGCAGGTATC 720
CTGCTGCGCT GCAAGCGGGA TGTGTTCCGG GGTGCCCGCT TCTCAGAGCT CCTGGCACCC 780
CAGGATGTGG GCGTCTTCTA TGGTTCCACT GCCCCATCTC GCTTGCCCAC CTGGGGCACT 840
GGGGCCTCAG CAGGTTCAGG CCCCAAGGAC TTCACCCAGG AGAAGTCTGT CTTCTGCCGT 900
ATCAGTGGAG GTCCTGACCG GGATTCAGGG CCTCGGTACC AGCCATTCCG CCTAACTCCA 960
TACGTGACCA AGATCCGGGT CTCGGATGGG GCCCCCGCAC AGCCGTGTTG CCTGCTCATT 1020
GCAGAGCGAA TCCACTCGGG TTATGAAGCT CCCCGGATTC CTCCTGACAA AAGGATTTTT 1080
ACTACTCGGC ACACACCCAG CTGCCTCTTC CAGGATGTGG ATGAGAGGGC GGCCCCACTG 1140
CTGGGCTACC TACCCCAGGA CCTCCTAGGG GCCCCCGTGC TCCTGTTCTT ACATCCTGAG 1200
GACCGACCCC TCATGCTGGC CATTCACAAG AAGATCCTCC AGCTGGCGGG CCAGCCGTTT 1260
GACCATTCCC CTATTCGCTT CTGTGCCCGT AATGGTGAAT ACGTCACCAT GGACACCAGC 1320
TGGGCCGGCT TTGTGCACCC TTGGAGCCGC AAGGTGGCGT TTGTGTTGGG CCGCCACAAA 1380
GTCCGCACGG CACCCCTGAA TGAGGACGTG TTCACTCCCC CGGCCCCCAG CCCAGCTCTG 1440
TCCCTGGACC CTGATATCCA GGAGCTCTCA GAGCAAATTC ACCGGCTGCT GTTACAGCCT 1500
GTACACAGCC CCAGCCCCAC GGGGCTCTGT GGAGTTGGCC CCGCGACCTC CCCAGGCCCT 1560
CTCCTCAGCC CTGGCTCCTC CAGCGATAGC AACAGGGGTG ATACCCAGGG GCCTGGGCCT 1620
CCCGGCCCGG TGACTTTCCA GCAGATCTGT AAGGACGTGC ATCTGGTGAA GCACCAGGGG 1680
CAGCAGCTTT TTATTGAGTC TCGGGTTCGG CCTCCACCCC GGCCCCGACT CCCTGCTACA 1740
GGCACATTCA AGGCCAAGGC CCTTCCCTGC CAGTCCCCAG AGCTGGAGGT GGCCCTTGCT 1800
CCTGTCCACG TCCCACTAGG CTTGGCCCAT GAGGAGGGTG AGAAGAAAGA AGCCTCCACC 1860
TGCTCCTACC AGCAGATTAA TTGCCTGGAC AGCATCCTCA GGTACCTGGA GAGTTGTAAC 1920
ATCCCCAACA CAACCAAGCG CAAGTGTGCC TCCTCCTCTT CCTGCACCAC CTCATCTGTC 1980
TCCGACGATG ACAAGCAGAG GGCAGGTCCT GTCCCCGCAA GTGTCAAAAA AGATCCAACG 2040
GCAGTGTTGT CTGGGGAGGG GGCCACCCCA CAGAAGGAGC CAGTGGTGGG AGGCAACCTG 2100
AGCCCTCTCG CCCTGGCCAA TAAGGCGGAG AGCGTGGTAT CCATCACCAG TCAGTGTAGC 2160
TTCAGCTCCA CCATCGTCCA TGTGGGAGAC AAGAAGCCCC CGGAGTCGGA CATTGTCATG 2220
ATGGAGGACC TGCCTGGTCT GGCCCCGGGC CCAGCCCCCA GCCCGGCCCC CAGCTCCACA 2280
GTAGCTCCTG ATCCAGCCCC AGATGCCTAC CGCCCTGTGG GCCTGACCAA GGCCGTGCTG 2340
TCCCTGCACA CACAGAAGGA GGAGCAGGCC TTCCTCAGCC GCTTCCGGGA CCTTGGCAGG 2400
CTACCGGGAC TCGACGGCTC TTCCCCAGCA CCATCGGCCC CTGGCTGTCA CCATGGCCCC 2460
GTAACTCCTG GCCGCCGGCA CCACTGTCGA TCCAAAGCCA AGCGCTCACG CCACCAGCAG 2520
ATCCCCCGGC CTGGAACCCC CTGCTATGTC TCCCAGCCCT CACCTGCACC ACCCTCTGCC 2580
CCCTGGCCCC CCCCACCAGC CACTACTCCC TTCTCAGCTG TGGTCCAGCC CTATCCCCTC 2640
CCGGTATTTT CCCCCAGAGG AGGCCCCCAG CCTCTGCCAC CTGCCCCCAC ACCTGTGCCC 2700
CCTGCAGCTT TCCCTGCCCC CCTGGTAACC CCAGTGGTGG CCTTGGTGCT CCCTAACTAT 2760
CTGTTCCCTA CCCCCTCTAG TTGTCCCTAT GGGGTACCCC AGGCTCCTGC TGAGGGGCCT 2820
CCCACTCCAG CCTCCCACTC CCCTTCTCCG TCCCTGCCCC CACCGCCCCC CAGCCCTCCC 2880
CACTGCCCGG ACTCTCCACT ATTCAACTCA AGGTGCAGCT CCCCGCTCCA GCTAAATCTG 2940
CTGCAGCTTG AAGAGCCCCC TCGTGCTGAG GGGGGTGCTG TTGCAGGGCC CCCAGGGAAC 3000
AGTGCTGGGC CCCCCCTTCC CAATGAGGAG GCTTTGGAGC CAGAGGCCAG ACTGGTGGAA 3060
GTGACTGAGT CCTCCAATCA GGACATGCTG TCGGGCTCCA GTGACCTGCT GGAGCTCCTG 3120
CTGCAAGAGG ACTCACGCTC GGGCACAGGC TCTGCCGCCT CGGGCTCCCT GGGCTCTGGC 3180
TTGGGCTCTG GGTCTGGCTC GGGCTCCCAC GCGGGGGGCA GCACCTCAGC CAGCGTCACC 3240
CGCAGCAGTC AGAGCAGCCA CACAAGCAAG TACTTCGGCA GCATCGACTC CTCGGAGGCC 3300
GAGGCGGGAA CGGCCCAGGC CGAGGCTGAG CCCGGGGACC AGGTCATGAA GTACGTGCTC 3360
CAGGACCCTC TCTGGCTGCT CCTGGCCAAC GCCGACCAGC GCGTCATGAT GACCTACCAG 3420
GTGCCGGCCA GGGACATGGC CTCTGTGCTG AAGCAGGACC GAGAGCGGCT CCGGGTCATG 3480
CAGAAGCAGC AGCCTCGGTT CTCGGAGGAC CAGCGGAGGG AACTGGGTGC TGTGCACTCC 3540
TGGGTCCGGA GGGGCCAGCT GCCTCGGGCC CTTGACGTGA TGGCTTGTGT GGACTGTGGT 3600
AGCAGCACCC AAGACCCTGG CCACCCTGAT GACCCACTCT TCTCGGAGCT GGATGTACTG 3660
GGGCTGGAGC CCATGGAAGA GGGCGGAGGC GAGGGTGTTG GTGGCAGTGA GGGCGGAGGA 3720
GGTGAGGGAG AGGGTGGAGG TGAGGCTGGG GCCCAAGCTG GGGCCATAGT CTCAAGCTCT 3780
CAGGACTTGG CCATGGAGGA GGAGGAACAA GGCGGGAGCT CATCCAGTCC AGCCTTACCT 3840
GCTCCAGTAA ATGGTACCAG C 3861
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus64.06 0.00e+00 1554.3
CGD-GaM-021007Gadus morhua52.59 0.00e+00 643.3
CGD-HoS-021038Homo sapiens (Human)64.11 0.00e+00 1568.9
CGD-OvA-022197Ovis aries65.2 0.00e+00 1533.9
CGD-RaN-021793Rattus norvegicus66.37 0.00e+00 1551.6
Gene Ontology

GO:0005515--protein binding
GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation