CGDB Gene Information

Tag Content
CGDB ID CGD-MyL-066363
Ensembl Accession ENSMLUP00000003294.2
Protein Name PER1
Ensembl Information ENSMLUG00000003612; ENSMLUT00000003619
Organism Myotis lucifugus
NCBI Taxa ID 59463
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSSPPEGADG GGDPRPGESI CPGGAPSPGP PQHRSCPGPS LADDTDANSN GSSGNESNGH 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSVAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCAMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGR IVYISEQAGI 240
LLHCKQDVFR GARFSELLAP QDVGVFYGST APSRLPTWGL GASAGSGFKD FTQEKSVFCR 300
IRGGPDRDPV PRYQPFRLTP YVTKIRVSEG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KVLQLAGQPF 420
DHSPIRFCAR NGEYVTMDSS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPVPSPAL 480
SLDPDIQELS EQIHRLLLQP VHSPSAVGLC GVGPVTSPGP LFSPGSSSDS NGGDAEGPGP 540
PAPVTFQQIC KDVHLVKHQG QQLFIESRAR PPLPRPRFPG PAIDTVKAKT LYCQSPDPEL 600
EADPALVQAP PAVAPEEAER KEASSCSYQQ INSLDSILRY LESCNIPGTI KRKCASSSSS 660
SSCTASSASD EDKQRTGPVP VGTKKDQSAV LSGEGATPRK EPVVGGTLTP LALANKAESV 720
VSVTSQCSFS STIVHVGDKK PPESDIVMME DLPGLAPCPA PSPTVAPDPA PDAYRPVGLT 780
KALLSLHTQK EEQAFLSRFR DLGRLRGLNG SSMAPSAPGE RGCHHGRTPP SRRYHCRSKA 840
KRSRHHQIPR VEAPCYVSHP SSVPPSAPWP PPPAATPFPA VVQPYPLPIF SPRDGPQPLS 900
PAPTSVSPAA FPAPLVTPVV ALVLPNYLFP TPSSYPYGVP QTPAEGPPTP VSHSPSPSLP 960
PPAPSPPHRP DSPLFNSRCS SPLQLNLLQL EESLRVEGGA AAGGPGSNAG PLPPSEETAE 1020
PEARLVEATE SSNQDALSGS SDLLELLLQE DSRSGTGSAA SGSLGSGLGS GSGSGSHEGG 1080
STSASITRSS QSSHTSKYFG SIDSSEAEAG AAQAKAEPGD QVIKYVLQDP IWLLMANADQ 1140
RVMMTYQVPS RDMASVLKQD RERLRAMQKQ QPRFSEDQRR ELGAVHSWVR KGQLPRVLDV 1200
MACVDCASST QNLGHPEDPL FSGLDGLGLE PMEEGGGEGG GGSCEDEGRD EAQAQAGAGV 1260
SSSQDLAMEE EEQGGSSSSP ALPATENGTS
Nucleotide Sequence
(Fasta)		 ATGAGTAGTC CCCCAGAAGG GGCTGATGGG GGAGGGGACC CCAGGCCAGG AGAATCCATT 60
TGTCCTGGAG GGGCGCCTTC CCCTGGGCCT CCACAGCACC GGTCCTGCCC TGGCCCCAGC 120
TTGGCTGATG ACACAGATGC CAACAGCAAT GGCTCAAGTG GCAATGAGTC CAACGGGCAT 180
GAGTCCAGGG GTGCATCTCA GCGGAGCTCA CATAGCTCCT CCTCTGGCAA TGGCAAGGAC 240
TCAGCCCTGC TGGAGACCAC TGAGAGCAGC AAGAGCACAA ACTCTCAGAG CCCATCCCCA 300
CCCAGCAGTT CCGTTGCCTA CAGCCTCCTG AGTGCCAGCT CAGAACAGGA CAACCCATCT 360
ACCAGTGGCT GCAGCAGCGA ACAATCAGCC CGTGCAAGAA CCCAGAAGGA ACTCATGACG 420
GCGCTGCGGG AGCTCAAGCT TCGGCTCCCG CCAGAACGCC GGGGCAAGGG CCGCTCGGGG 480
ACCCTGGCCA CACTGCAGTA TGCACTGGCC TGTGTCAAGC AGGTGCAGGC CAACCAGGAG 540
TACTACCAGC AGTGGAGCCT GGAGGAAGGT GAGCCATGTG CCATGGACAT GTCCACCTAC 600
ACTCTGGAGG AGCTGGAGCA CATCACGTCT GAGTACACAC TTCGCAACCA GGATACCTTC 660
TCCGTGGCTG TCTCCTTCCT GACAGGCCGA ATCGTCTACA TTTCGGAGCA GGCAGGTATC 720
CTGCTGCACT GCAAGCAGGA CGTGTTCCGG GGTGCCCGCT TCTCAGAGCT CCTGGCTCCC 780
CAGGACGTGG GCGTCTTCTA TGGTTCCACG GCCCCATCTC GTCTGCCTAC CTGGGGCCTG 840
GGGGCTTCGG CAGGTTCAGG CTTCAAGGAC TTCACCCAGG AGAAGTCTGT CTTTTGCCGT 900
ATCAGAGGAG GTCCTGACCG GGACCCAGTG CCGCGGTACC AACCATTTCG CCTAACCCCA 960
TATGTGACCA AAATCCGGGT ATCAGAAGGG GCTCCCGCAC AGCCATGCTG CCTGCTCATT 1020
GCAGAGCGAA TCCACTCGGG TTATGAAGCT CCCCGGATAC CGCCCGACAA GAGGATCTTC 1080
ACTACACGGC ACACGCCCAG CTGCCTCTTT CAGGATGTGG ATGAAAGGGC TGCCCCCCTG 1140
CTGGGCTACC TCCCCCAGGA TCTCCTGGGG GCCCCAGTGC TCCTGTTCCT GCATCCTGAG 1200
GACCGACCCC TCATGCTGGC CATCCACAAG AAGGTCCTGC AGCTGGCTGG CCAGCCCTTT 1260
GACCACTCTC CCATTCGTTT CTGCGCACGT AATGGGGAAT ATGTTACCAT GGACAGCAGC 1320
TGGGCTGGCT TCGTGCACCC CTGGAGCCGC AAGGTGGCCT TTGTGTTGGG CCGCCACAAA 1380
GTCCGCACGG CACCCCTGAA TGAGGACGTA TTCACTCCTC CAGTCCCCAG CCCTGCTCTT 1440
TCCCTGGACC CTGATATCCA AGAGCTATCT GAGCAAATCC ATCGGCTGCT GTTACAGCCT 1500
GTGCACAGCC CCAGTGCCGT GGGGCTCTGT GGAGTTGGCC CTGTGACTTC CCCAGGCCCT 1560
CTCTTCAGCC CAGGCTCGTC TAGTGACAGC AACGGGGGTG ATGCCGAGGG GCCTGGGCCT 1620
CCTGCCCCGG TGACCTTCCA GCAGATCTGT AAGGATGTGC ATCTGGTGAA GCACCAGGGG 1680
CAGCAGCTTT TTATCGAGTC CCGGGCTCGG CCTCCTCTTC CCCGGCCCCG CTTCCCTGGC 1740
CCAGCTATAG ACACAGTCAA GGCCAAGACC CTTTACTGCC AGTCCCCAGA CCCAGAGCTG 1800
GAGGCAGACC CTGCTCTAGT CCAGGCCCCA CCAGCCGTGG CCCCTGAGGA GGCTGAGAGG 1860
AAAGAAGCCT CCAGTTGCTC CTACCAGCAG ATCAACTCCC TGGACAGCAT CCTCAGGTAC 1920
CTGGAGAGCT GCAACATCCC AGGCACCATC AAGCGTAAAT GTGCCTCCTC CTCTTCCTCC 1980
TCCTCCTGTA CCGCCTCCTC GGCCTCTGAT GAAGACAAGC AGAGGACAGG TCCAGTCCCT 2040
GTGGGGACCA AGAAAGATCA ATCGGCAGTG CTGTCGGGGG AGGGGGCCAC CCCTCGGAAG 2100
GAGCCGGTGG TGGGAGGCAC CCTGACCCCG CTCGCCCTGG CCAATAAGGC GGAGAGCGTG 2160
GTGTCCGTCA CCAGTCAGTG TAGCTTCAGC TCCACCATCG TCCATGTGGG AGACAAGAAG 2220
CCCCCGGAGT CGGACATCGT CATGATGGAG GACCTGCCTG GCCTGGCTCC GTGCCCAGCC 2280
CCCAGCCCCA CGGTGGCCCC TGACCCAGCC CCAGATGCCT ACCGCCCCGT GGGCCTGACC 2340
AAGGCCTTGC TGTCTCTGCA CACACAGAAG GAGGAGCAGG CCTTCCTCAG CCGCTTCCGG 2400
GACCTCGGCC GGCTGCGCGG ACTCAATGGC TCCTCCATGG CTCCCTCGGC CCCTGGAGAG 2460
CGAGGCTGCC ACCATGGCCG CACACCCCCC AGCCGCCGAT ACCACTGCCG GTCTAAAGCC 2520
AAGCGCTCAC GTCACCACCA GATCCCTCGG GTGGAAGCCC CCTGCTATGT GTCCCACCCC 2580
TCATCTGTCC CACCCTCTGC CCCCTGGCCC CCACCACCAG CCGCTACTCC CTTCCCAGCT 2640
GTGGTACAGC CCTACCCCCT CCCAATATTC TCCCCCCGAG ATGGTCCCCA GCCTCTTTCC 2700
CCGGCCCCCA CATCTGTGTC CCCTGCAGCT TTTCCTGCCC CCCTGGTGAC CCCAGTTGTA 2760
GCCTTGGTAC TACCTAACTA TCTGTTCCCT ACGCCATCCA GCTATCCCTA TGGGGTACCT 2820
CAGACTCCTG CCGAGGGTCC TCCTACCCCT GTGTCCCACT CCCCTTCTCC ATCCCTGCCC 2880
CCGCCAGCCC CCAGCCCTCC CCACCGCCCA GACTCTCCAC TGTTCAACTC GCGGTGCAGC 2940
TCCCCACTCC AGCTAAATCT GCTGCAGCTT GAGGAGTCCC TCCGTGTTGA GGGGGGTGCT 3000
GCTGCAGGGG GCCCTGGGAG CAATGCTGGG CCCCTGCCTC CCAGTGAGGA GACTGCTGAG 3060
CCAGAGGCCA GACTGGTGGA GGCAACTGAG TCCTCCAATC AGGATGCACT TTCGGGCTCC 3120
AGTGACCTCC TGGAATTGTT GCTGCAAGAA GACTCTCGCT CGGGCACAGG CTCTGCTGCC 3180
TCCGGCTCCT TGGGCTCTGG CTTGGGCTCT GGGTCTGGTT CAGGCTCCCA TGAGGGGGGC 3240
AGCACCTCAG CCAGCATCAC ACGAAGCAGT CAGAGTAGCC ACACAAGCAA GTACTTCGGC 3300
AGCATCGACT CTTCTGAAGC TGAGGCTGGG GCTGCCCAGG CCAAGGCTGA GCCCGGGGAC 3360
CAGGTCATTA AGTACGTGCT CCAGGATCCC ATCTGGCTGC TCATGGCCAA TGCTGACCAG 3420
CGTGTCATGA TGACCTACCA GGTGCCCTCC AGGGACATGG CCTCTGTGCT GAAGCAGGAC 3480
CGGGAGCGGC TCCGGGCCAT GCAAAAGCAG CAGCCTCGGT TTTCGGAGGA CCAGCGGAGG 3540
GAACTGGGTG CCGTGCACTC CTGGGTCCGG AAGGGCCAGC TGCCTCGGGT CCTTGATGTG 3600
ATGGCCTGTG TGGACTGCGC TAGTAGCACC CAAAACCTTG GCCACCCTGA AGACCCACTC 3660
TTCTCAGGAC TGGATGGATT GGGGCTGGAG CCCATGGAGG AGGGTGGAGG CGAAGGTGGT 3720
GGTGGCAGTT GTGAGGATGA GGGCAGAGAT GAGGCCCAGG CCCAAGCTGG GGCTGGGGTC 3780
TCAAGCTCTC AGGACCTGGC CATGGAGGAG GAGGAACAAG GTGGGAGCTC ATCCAGTCCA 3840
GCCTTACCTG CCACAGAAAA TGGCACCAGC TAA 3873
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus63.66 0.00e+00 1529.6
CGD-GaM-021007Gadus morhua53.02 0.00e+00 634
CGD-HoS-021038Homo sapiens (Human)66.26 0.00e+00 1546.2
CGD-OvA-022197Ovis aries65.07 0.00e+00 1505
CGD-RaN-021793Rattus norvegicus65.36 0.00e+00 1515.4
Gene Ontology

GO:0005515--protein binding
GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0051591--response to cAMP
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus