CGDB Gene Information

Tag Content
CGDB ID CGD-CaF-064770
Ensembl Accession ENSCAFP00000025009.4
Protein Name PER1
Ensembl Information ENSCAFG00000016984; ENSCAFT00000026906
Organism Canis familiaris
NCBI Taxa ID 9615
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSGPLEGADG GGDPGPGESF CPGGAPSPGP LQHPSCPGPG LADDTDANSN GSSGNESNGP 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCAMDMSVY TLEELEHVTS EYTLRNQDTF SVAVSFLTGR IVYISEQAGV 240
LLRCKRDVFR GTRFSELLAP QDVGVFYGST APSRLPTWGA GASAGSGLKD FTQEKSVFCR 300
IRGGPDRDSG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAL 480
SLDSDIQELS EQIHRLLLQP VHSPSPSGLC GVGPITSPGP LLSPGSSSDS NGGDAEGPGP 540
PAPVTFQQIC KDVHLVKHQG QQLFIESRAR PMPRPRLPAT GMFKAKTLSG QFPDPELEMV 600
PAPGPAPLTL TPEEAERKEA SSCSYQQINC LDSILRYLES CNIPSTTKRK CASSSSCTTS 660
SASDDDKQRT GPVPLGTKKD PPAVLSGEGA SLQKEPVVGG ALSPLALANK AESVVSVTSQ 720
CSFSSTIVHV GDKKPPESDI IMMEDLPGLA PGPAPSPAPS PTVAPDPAPD AYRPVGLTKA 780
VLSLHTQKEE QAFLSRFRDL GRLRAFDSSS PAPLAPGERG CHHGPAPPGR RHHCRSKAKR 840
SRHHQTPRAE APCYGSHPPP VSPSAPWPPP PATTPFPAVV QPYPLPVFSP RGGSQSLASA 900
PTAGPPAAFP APLVTPMVAL VLPNYLFPTP SGYPYGVPQT PAEGPPTPAS HSPSPSLPPP 960
PPSPPRRSDS PLFNSRCSSP LQLNLLQLEE PPRVEGGATA GGPGSSAGPP PPSEETAEPE 1020
ARLVEVTESS NQDALSGSSD LLELLLQEDS RSGTGSAASG SLGSGLGSGS GLGSHEGGST 1080
SASITRSSQS SHTSKYFGSI DSSEAEAGAA QARAEPGDQV IKYVLQDPIW LLMANADQRV 1140
MMTYQVPSRD MATVLKQDRE RLRAMQKQQP RFSEDQRREL GAVHSWVRKG QLPRALDVMA 1200
CVDCGSSTQD PGHPNDPLFS ELDGLGLEPM EEGGGEGGGE GGGEGGGGEG EGGEEAQAQA 1260
GARVSSSQDL AMEEEEQGGS SSSPALPATE NGTS 1294
Nucleotide Sequence
(Fasta)		 NNNNNNNNNN NNNNNNNNNN NNNNNTCGGG GGCGGGGCCT GCGGCTCCGC GGCAGGAGGC 60
CAATGTGGGG CAGTGCCTGG CATTATGCAA CCCGCCTCCT GGCCCCGCGA AGCTTCCACT 120
CGGCGGAGGG CTGCAACGGC GGCGGGCAGG AGGCCGGAGA GAGCTCGCGC GGCCAGGTGC 180
TGTCTGTGAT CGAACTTCTC AACCCTCTCA CCTCACTCCC CCAGCCAGGC CGCCCGGCCC 240
CCTTGTGTGC TCGTGGTGGC CTCTCTGCCT TCCCTGTTTT CCTCCTGCCC TCCCCATGGC 300
CCAGACATGA GCGGCCCCCT AGAAGGGGCT GATGGGGGAG GGGACCCAGG GCCAGGGGAG 360
TCCTTTTGCC CTGGAGGGGC CCCATCCCCT GGGCCTCTAC AGCACCCGTC TTGCCCTGGC 420
CCTGGCCTGG CAGATGACAC AGATGCCAAC AGCAATGGCT CCAGCGGCAA TGAATCCAAT 480
GGGCCAGAGT CCAGGGGAGC ATCTCAGCGC AGCTCCCATA GCTCCTCTTC TGGCAATGGC 540
AAGGACTCCG CCCTGCTGGA GACCACTGAG AGCAGCAAGA GCACAAACTC TCAGAGTCCA 600
TCCCCACCCA GCAGTTCCAT TGCCTACAGC CTCCTGAGTG CCAGCTCAGA GCAGGACAAC 660
CCGTCTACCA GTGGCTGCAG CAGTGAACAG TCAGCTCGGG CAAGGACCCA GAAGGAACTT 720
ATGACGGCTC TGCGGGAGCT CAAGCTTCGG CTGCCGCCAG AGCGCCGGGG CAAGGGCCGC 780
TCTGGGACCC TGGCCACGCT ACAGTATGCT CTGGCCTGTG TCAAGCAGGT GCAGGCCAAC 840
CAGGAATACT ACCAACAGTG GAGCCTGGAG GAGGGTGAGC CTTGTGCCAT GGATATGTCC 900
GTCTACACCT TGGAGGAGCT GGAGCACGTC ACGTCTGAGT ACACGCTTCG CAACCAGGAT 960
ACCTTCTCCG TGGCTGTCTC CTTCCTGACA GGCCGCATCG TCTACATTTC TGAGCAGGCA 1020
GGCGTCCTGC TGCGCTGCAA GCGGGATGTG TTCCGGGGCA CCCGCTTCTC AGAGCTGCTG 1080
GCTCCCCAGG ACGTGGGCGT CTTCTATGGT TCCACTGCCC CCTCTCGCCT GCCCACCTGG 1140
GGTGCTGGGG CCTCAGCAGG TTCGGGCCTC AAGGACTTCA CCCAGGAGAA GTCTGTCTTC 1200
TGCCGTATCA GAGGAGGTCC TGACCGGGAT TCAGGGCCTC GGTACCAGCC ATTCCGCCTA 1260
ACGCCATATG TGACCAAGAT CCGGGTCTCA GACGGGGCGC CTGCACAGCC ATGCTGCCTG 1320
CTCATCGCTG AGCGCATCCA CTCGGGTTAT GAAGCTCCCC GGATCCCCCC TGACAAAAGG 1380
ATCTTCACCA CTCGGCATAC ACCCAGCTGC CTCTTCCAGG ATGTGGATGA AAGGGCTGCC 1440
CCACTGCTGG GCTACCTCCC CCAGGACCTC TTGGGAGCTC CAGTGCTCCT GTTCTTGCAT 1500
CCCGAGGACC GACCCCTCAT GCTGGCCATC CATAAGAAGA TCCTGCAGTT GGCTGGTCAG 1560
CCCTTCGACC ACTCCCCTAT CCGTTTCTGC GCCCGCAATG GGGAGTATGT CACCATGGAC 1620
ACCAGTTGGG CCGGCTTCGT GCACCCTTGG AGCCGTAAGG TGGCCTTTGT CTTGGGCCGC 1680
CACAAAGTAC GCACGGCACC CCTGAATGAG GATGTGTTCA CTCCCCCGGC CCCTAGCCCG 1740
GCTCTGTCTC TGGACTCTGA TATCCAGGAG CTCTCGGAGC AGATCCACCG GTTGCTATTA 1800
CAGCCTGTGC ACAGCCCCAG TCCCAGTGGG CTCTGTGGAG TGGGCCCCAT CACTTCCCCA 1860
GGCCCTCTCC TCAGCCCTGG CTCCTCCAGT GATAGCAACG GGGGTGATGC CGAGGGGCCT 1920
GGGCCTCCTG CACCGGTGAC CTTTCAGCAG ATCTGTAAGG ATGTGCATCT GGTGAAGCAC 1980
CAGGGCCAGC AACTTTTTAT TGAGTCCCGT GCTCGGCCTA TGCCCCGGCC CCGCCTCCCT 2040
GCTACAGGCA TGTTCAAGGC CAAGACACTT TCTGGTCAGT TCCCGGACCC AGAACTGGAG 2100
ATGGTCCCTG CTCCAGGCCC AGCCCCACTC ACCTTGACTC CTGAGGAGGC TGAAAGGAAA 2160
GAAGCCTCCA GTTGTTCCTA CCAGCAGATT AACTGCCTGG ACAGCATCCT CAGGTACCTG 2220
GAGAGCTGTA ACATCCCTAG CACGACCAAG CGTAAATGTG CCTCCTCTTC CTCCTGCACC 2280
ACCTCATCGG CCTCCGACGA TGACAAGCAG AGGACGGGTC CAGTCCCTTT GGGGACCAAG 2340
AAAGATCCAC CGGCAGTGCT GTCTGGGGAG GGGGCCAGCC TGCAGAAGGA GCCAGTGGTG 2400
GGAGGCGCCC TGAGCCCGCT CGCCCTGGCC AATAAGGCAG AGAGCGTGGT ATCTGTCACC 2460
AGCCAGTGTA GCTTCAGCTC CACCATCGTC CATGTGGGAG ACAAGAAGCC CCCGGAGTCG 2520
GACATCATCA TGATGGAGGA CCTGCCTGGC CTGGCTCCGG GCCCAGCCCC CAGCCCAGCC 2580
CCCAGCCCCA CGGTAGCCCC TGACCCTGCC CCAGATGCCT ACCGCCCAGT GGGCCTGACC 2640
AAGGCCGTGC TGTCCCTGCA CACACAGAAG GAGGAGCAGG CCTTCCTCAG CCGCTTCCGA 2700
GACCTTGGCC GACTGCGGGC GTTCGACAGC TCTTCCCCGG CCCCCCTGGC CCCTGGCGAG 2760
CGAGGCTGCC ACCATGGCCC CGCTCCCCCC GGTCGCCGAC ACCACTGCCG ATCCAAAGCC 2820
AAGCGGTCAC GCCACCACCA GACCCCCCGG GCCGAAGCCC CCTGCTATGG CTCCCACCCG 2880
CCACCTGTGT CACCCTCCGC CCCCTGGCCC CCCCCACCTG CCACTACTCC CTTCCCGGCT 2940
GTCGTCCAGC CCTACCCTCT CCCGGTGTTC TCCCCTCGGG GAGGCTCCCA GTCTCTTGCC 3000
TCTGCCCCTA CAGCTGGGCC CCCTGCAGCC TTCCCTGCCC CGCTCGTGAC CCCAATGGTG 3060
GCCTTGGTGC TTCCTAACTA TCTGTTCCCT ACCCCGTCTG GCTACCCCTA TGGGGTCCCC 3120
CAGACGCCTG CAGAAGGGCC TCCCACCCCT GCCTCCCACT CCCCTTCTCC GTCCCTGCCC 3180
CCACCACCCC CCAGCCCTCC CCGCCGGTCG GACTCGCCTC TGTTCAACTC GAGATGCAGC 3240
TCCCCGCTCC AGCTAAACCT GCTGCAGCTT GAGGAGCCCC CCCGTGTTGA GGGGGGTGCC 3300
ACGGCGGGGG GCCCTGGGAG TAGTGCTGGG CCCCCGCCTC CCAGTGAGGA GACTGCTGAG 3360
CCAGAGGCCA GACTGGTGGA GGTGACAGAG TCCTCCAACC AGGACGCGCT GTCCGGCTCC 3420
AGTGACCTGC TGGAGTTGCT GCTGCAGGAG GACTCTCGAT CTGGCACAGG CTCTGCTGCC 3480
TCGGGCTCCT TGGGCTCCGG CTTGGGCTCT GGGTCTGGCT TAGGCTCCCA TGAGGGAGGA 3540
AGCACCTCAG CCAGCATCAC ACGCAGCAGT CAGAGCAGCC ACACGAGCAA GTACTTTGGC 3600
AGCATCGACT CTTCAGAGGC TGAAGCAGGG GCTGCTCAGG CCAGGGCTGA GCCTGGGGAC 3660
CAGGTCATAA AGTACGTGCT CCAGGATCCC ATCTGGCTGC TCATGGCCAA CGCTGACCAG 3720
CGTGTCATGA TGACCTACCA GGTGCCCTCC AGGGACATGG CCACTGTGCT GAAGCAGGAT 3780
CGGGAGCGGC TGCGGGCCAT GCAGAAGCAG CAGCCTCGGT TTTCAGAGGA CCAGCGCAGG 3840
GAACTGGGTG CTGTGCACTC CTGGGTCCGG AAGGGTCAGC TGCCTCGGGC CCTCGATGTG 3900
ATGGCCTGCG TGGACTGCGG TAGTAGCACC CAAGACCCCG GCCACCCCAA TGACCCCCTC 3960
TTCTCAGAAC TGGATGGACT GGGACTGGAG CCTATGGAGG AGGGTGGAGG CGAGGGCGGA 4020
GGCGAGGGTG GAGGTGAGGG TGGGGGTGGT GAGGGTGAGG GCGGAGAAGA GGCCCAGGCT 4080
CAAGCTGGGG CCAGAGTCTC CAGCTCTCAG GACCTGGCAA TGGAGGAGGA GGAACAAGGG 4140
GGGAGCTCAT CCAGTCCAGC CTTACCTGCC ACAGAAAATG GCACCAGTTA GACCACATTT 4200
GGGGGCCCCC TCCGAGAGTG CATGAGAAGC TTCCTTCTCC CATGTTCCAC CTCTCAGAAC 4260
TCGGATGTGG CTGGACCAAC CAATAGGAGA CTGGCCTGGC TTCTCCCACT TAGGGGGCGG 4320
GACCCCCGCC AGCAGCCCAG GGTACAGGGG CTGCCAGGGC TTCTGAGGGG GCACAGGGTG 4380
GGATTCATAA ACCCGGCCCA GAGAAGCCTC ATTTCCCACC TCTGGTGAAG AGCCCTTCCT 4440
TCCCCTGGGC AAGGTTGCTG ACAAGCTGCT GAAGTGGTCT CTCCAAGTCC CGGCTGAGCC 4500
CAGTCCCGGC TGAGCCCAGT CCCGGTCCCT GAGGGTTGGG GCTGCACTTA TTTATTGGGG 4560
GGAGACAGCT CTCTCTCACC TCCTCCCTGG GTGGGAGGAG GAGGGCCTGA GGCCCAAACA 4620
GGACCCAGCG GTCCAAACCC CTAGCTGCTC CAGGGTGGGG GAGGTTGGTG GACCATGGAG 4680
TCCCTGGTGC TGCCCCTCAG GTGGGACCCA GGTGTTCTCA GCTGTACCCT CTACCGATGG 4740
CATTTGTGTT TTTGATATTG TGTCTTGTTA TTTTTTAATA CAAAGAGAGA AAAACAAACC 4800
ACCCCGGCCT TTGTGGAATG AAATGTAGGG TTGGGGGGAG GTGTGGCCCC GCTTTCGTGT 4860
GTGTGTGTGT GTGTGTGTGT GTGTGCGCGC GCGTGTGCGC CCGCGCGCGC GCAGGGAGAG 4920
TGACCGCCCC CTGCCCTGGT ACCCCCAGCC CTTGGCGCGG GGCACCCCTG CGGGCAGAAG 4980
GGCCTTGCCC TGCCTGTAGC ATCTCCTCGG CCCCGGGCGG CTGGTGCCGT CGGGCTCGCC 5040
CGCAGAGAGG GGAGCCCGCC CGGCGTGCAG GGGCCCCGAA GCAGGTGAGG GTGCTGCTCT 5100
GGCACCGGAT CCCACGCAGC AGAGGGCCCC GTCGACGGGG GCTATGGGGC GTCAGCTCAC 5160
GTACCCACTC AACGCTCCGG
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus62.28 0.00e+00 1461
CGD-GaM-021007Gadus morhua53.26 7.00e-178 621.7
CGD-HoS-021038Homo sapiens (Human)62.18 0.00e+00 1470.3
CGD-OvA-022197Ovis aries61.11 0.00e+00 1416
CGD-RaN-021793Rattus norvegicus62.62 0.00e+00 1406.7
Gene Ontology

GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0005515--protein binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation