CGDB Gene Information

Tag Content
CGDB ID CGD-MaE-058204
Ensembl Accession ENSMEUP00000000511.1
Protein Name PER1
Ensembl Information ENSMEUG00000000532; ENSMEUT00000000558
Organism Macropus eugenii
NCBI Taxa ID 9315
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 12 ZT 0 LD 18 jejunum Predicted from orthologs Q8CHR1
CT 12 CT 0 DD3 100 liver Predicted from orthologs Q8CHR1
ZT 12 ZT 4 LD 20 liver Predicted from orthologs Q8CHR1
ZT 12 ZT 4 LD 3 pituitary gland Predicted from orthologs Q8CHR1
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MNGAIEGGSG AGGSGPGRFD SGPSPGPPEH RPCPGPGLAD DTDANSNGSS GNESNGPESQ 60
GTSQHSSHSS SSGHGKDSAL LETTESSKST NSQSPSPPSS SIAYSLLSAS SEQDNPSTSG 120
CSSEQSARAR TQKELMTALR ELKRRLPPER RGKGRSGTLA TLQYALACVK QVQANQDYYQ 180
QWSLEEGQPC SMDMSSYTLE ELEHITSEYT LRNQDTFSVA VSFLTGRIVY ISDQAAILLR 240
CKKEVFRGAR FSELLAPQDV GVFYGSTAPS RLPTWGSRAS AGSGPMDFTQ EKSVFCRIRG 300
GPDREPSPRY QPFRLTPYVT KIQLSXXXXX XXXXXXXXXX XXXXXXXPRI PPDKRIFTTR 360
HTPSCLFQDV DERAAPLLGY LPQDLLGAPV LLFLHPEDRP LMLAIHKKXX XXXXXXXXXX 420
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 480
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 540
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 600
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX 660
XXXXXXXXXX XXXXXXXPPE ELSREGAPLQ KEPVVGGPLT PLTLANKAES VVSITSQCSF 720
SSTIVHVGDK KPPESDIVMM EELPGLTSGP APSPTMATPD PTPDAYRPVG LTKAVLSLHT 780
QKEEQAFLTR FRDLSRLRVF DTPSMGPSPP VDRGFCHGPT PSGRRHHGKS KAKRSRHHQL 840
PLTEAPGYTS HPSSTPPTTP WPSQPTPPTS AAFPTVVQTY PLPIFSTRGC PQPSAPTPSP 900
SPFSSPLVTP MVALVLPNYL FPSAPTSYPC GAPQALSDRP LTPAPCSPSP SLPPLPPSPP 960
QCPDSPLFNS RCSSPLQLNL LQLEETTRGE GGAAVGXXXX XXXXXXXXXX XXXXXXXXVE 1020
MNESSNQDAL SGSSDLLELL LQEDSRSGTG SAASGSLGSG SGSGSGSGSH GGSTSASITR 1080
SSQSSHTSKY FGSIDSSEAE PTGTDWGGAG PGEQVIKYVL QDPIWLLMAN ADHRVMMTYQ 1140
VPSRDTASVL QRDRERLRAM QKQQPRFSEE QRRELGAVHA WVRKGQLPQA LDVMTCVDCG 1200
SSTPDPQYPD DTLFPELDGL GLEPMEEDGG GSPDTAMDEE EQGGEPTTSE LPSENTS 1257
Nucleotide Sequence
(Fasta)		 ATGAATGGCG CCATTGAGGG AGGCAGTGGG GCAGGGGGAT CAGGCCCTGG GAGGTTTGAT 60
TCAGGGCCAT CCCCTGGACC CCCCGAACAC AGACCCTGCC CTGGTCCTGG CCTCGCGGAT 120
GATACAGATG CAAACAGCAA TGGTTCAAGT GGCAATGAGT CCAATGGACC GGAGTCCCAG 180
GGTACTTCCC AGCATAGTTC CCACAGCTCT TCTTCTGGCC ATGGGAAGGA CTCTGCCCTG 240
CTGGAGACGA CAGAGAGCAG CAAGAGCACC AACTCTCAGA GCCCATCCCC TCCAAGCAGT 300
TCCATTGCCT ACAGCCTCCT GAGTGCCAGC TCTGAGCAGG ATAACCCTTC AACCAGTGGC 360
TGCAGCAGTG AGCAGTCAGC CCGAGCTCGA ACACAGAAGG AGCTGATGAC TGCCCTCCGA 420
GAGCTGAAAC GTAGACTCCC ACCAGAGCGC CGAGGGAAGG GTCGATCAGG GACTTTGGCC 480
ACACTGCAAT ATGCACTTGC CTGTGTTAAA CAAGTCCAGG CCAATCAAGA TTACTACCAG 540
CAGTGGAGCT TAGAGGAGGG GCAGCCTTGC TCCATGGACA TGTCCAGCTA TACCTTGGAG 600
GAGTTAGAGC ACATCACATC TGAGTACACT CTTCGAAATC AGGACACTTT CTCGGTGGCT 660
GTCTCTTTTC TCACTGGCCG GATTGTCTAC ATTTCGGATC AAGCAGCTAT TCTTCTGCGT 720
TGCAAGAAAG AAGTCTTCCG GGGTGCCCGG TTCTCAGAAC TGTTGGCCCC TCAGGATGTT 780
GGTGTCTTCT ATGGCTCCAC TGCCCCCTCT CGCTTACCCA CGTGGGGTTC CCGGGCCTCT 840
GCTGGTTCAG GTCCCATGGA TTTCACACAG GAGAAATCAG TCTTCTGCAG GATCAGAGGT 900
GGCCCAGATC GGGAACCAAG TCCCCGATAC CAGCCATTTC GACTGACTCC CTATGTGACT 960
AAGATCCAGC TCTCAGANNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1020
NNNNNNNNNN NNNNNNNNNC TCCCAGGATT CCCCCCGACA AGAGGATCTT CACGACACGG 1080
CACACACCTA GCTGTCTGTT CCAAGATGTA GATGAGAGGG CTGCCCCGTT GCTGGGATAC 1140
TTGCCCCAGG ATCTGCTGGG GGCCCCAGTG CTCCTTTTTT TACACCCTGA AGACCGACCT 1200
CTCATGTTGG CAATCCACAA AAAGANNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1260
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1320
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1380
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1440
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1500
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1560
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1620
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1680
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1740
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1800
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1860
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1920
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 1980
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNA TCCACCAGAA 2040
GAACTGTCCC GGGAGGGGGC CCCCCTCCAG AAGGAGCCAG TGGTGGGAGG TCCACTGACC 2100
CCTCTCACCC TTGCCAATAA GGCAGAGAGT GTGGTATCCA TCACCAGTCA GTGTAGCTTC 2160
AGCTCTACAA TCGTCCATGT AGGAGACAAG AAGCCCCCGG AGTCGGATAT TGTCATGATG 2220
GAGGAGTTGC CTGGCCTGAC CTCTGGTCCA GCTCCCAGTC CAACAATGGC CACTCCTGAC 2280
CCCACTCCTG ATGCCTATCG CCCTGTGGGA TTGACCAAAG CTGTATTGTC ACTTCACACA 2340
CAGAAGGAGG AACAGGCCTT CCTTACCCGA TTTCGGGATC TTAGCAGACT CCGTGTCTTT 2400
GATACCCCTT CCATGGGACC TTCACCCCCT GTTGATCGAG GCTTCTGCCA TGGTCCTACT 2460
CCTTCTGGCC GCCGCCACCA TGGCAAATCA AAAGCCAAAC GTTCGAGGCA CCATCAGCTT 2520
CCTCTGACTG AGGCTCCTGG CTATACCTCC CATCCCTCCT CAACACCTCC AACCACTCCA 2580
TGGCCCTCTC AACCCACCCC ACCCACATCT GCTGCTTTCC CAACAGTGGT GCAAACCTAC 2640
CCCCTCCCCA TTTTTTCAAC CAGAGGTTGC CCTCAACCTT CAGCTCCTAC CCCATCTCCT 2700
TCTCCCTTTT CTTCCCCCTT GGTAACTCCT ATGGTAGCCT TGGTCCTACC CAACTATTTG 2760
TTTCCTTCTG CCCCCACCAG TTACCCCTGT GGGGCTCCTC AGGCTCTCTC AGATAGGCCT 2820
CTCACTCCTG CACCCTGTTC ACCTTCCCCA TCTTTACCTC CTCTGCCCCC TAGCCCTCCC 2880
CAATGCCCTG ATTCACCCCT GTTCAACTCA CGGTGCAGTT CCCCACTCCA GCTGAACCTG 2940
CTGCAGCTTG AGGAGACTAC TCGGGGGGAA GGAGGAGCCG CAGTTGGGGN NNNNNNNNNN 3000
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNGTGGAG 3060
ATGAATGAAT CCTCTAATCA GGATGCACTG TCAGGCTCCA GTGACCTGTT GGAGCTGTTG 3120
CTCCAGGAGG ACTCCAGATC TGGCACTGGC TCAGCTGCAT CGGGCTCCCT GGGCTCTGGC 3180
TCTGGCTCTG GCTCCGGCTC CGGCTCCCAT GGTGGTAGCA CCTCAGCCAG TATCACTCGC 3240
AGCAGCCAGA GCAGCCACAC CAGCAAGTAT TTTGGGAGTA TTGACTCCTC TGAGGCTGAG 3300
CCAACAGGGA CCGATTGGGG TGGGGCAGGG CCTGGCGAAC AGGTCATTAA GTATGTTCTG 3360
CAAGATCCCA TCTGGCTACT CATGGCTAAT GCTGACCATA GGGTCATGAT GACCTATCAA 3420
GTGCCCTCCA GGGATACGGC TTCAGTGCTG CAACGGGACC GAGAGAGGCT CCGTGCCATG 3480
CAAAAACAAC AGCCTCGGTT TTCAGAAGAG CAGCGTCGGG AGCTGGGTGC TGTGCATGCC 3540
TGGGTGCGGA AGGGCCAGCT GCCCCAGGCC CTGGATGTGA TGACTTGTGT AGATTGTGGC 3600
AGCAGCACTC CAGATCCACA GTATCCGGAT GACACACTTT TCCCTGAGCT GGATGGATTG 3660
GGGCTAGAGC CGATGGAGGA GGATGGGGGT GGCTCCCCAG ACACAGCCAT GGATGAAGAG 3720
GAACAAGGTG GGGAGCCAAC TACTTCAGAG TTACCTTCTG AAAACACCAG CTAA 3774
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus50.99 2.00e-146 517.3
CGD-HoS-021038Homo sapiens (Human)50 3.00e-143 508.1
CGD-MuM-021794Mus musculus (Mouse)49.67 5.00e-139 493.8
CGD-OvA-022197Ovis aries49.34 9.00e-137 485.3
CGD-RaN-021793Rattus norvegicus53.06 1.00e-139 495.4
Gene Ontology

GO:0005515--protein binding
GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation