CGDB Gene Information

Tag Content
CGDB ID CGD-PaA-057182
Ensembl Accession ENSPANP00000019661.1
Protein Name PER1
Ensembl Information ENSPANG00000023840; ENSPANT00000022977
Organism Papio anubis
NCBI Taxa ID 9555
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 12 ZT 0 LD 18 jejunum Predicted from orthologs Q8CHR1
CT 12 CT 0 DD3 100 liver Predicted from orthologs Q8CHR1
ZT 12 ZT 4 LD 20 liver Predicted from orthologs Q8CHR1
ZT 12 ZT 4 LD 3 pituitary gland Predicted from orthologs Q8CHR1
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MWMKGLAPLL GYLPHGPPRG PDVLLFLHPE DRPLMLAIHK KILQLAGQPF DHSPIRFCAR 60
NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAP TLDTDIQELS 120
EQIHRLLLQP VHSPSPTGLC GVGPVTSPGL LHSPGSSSDS NGGDAEGPGP PAPVTFQQIC 180
KDVHLVKHQG QQLFIESRAR PQPRPRLPAT GTFKARALPC QSPDPELETG SAPIPAPLAL 240
APEEAERKEA SSCSYQQINC LDSILRYLES CNLPSTTKRK CASSSSYTTS SASDDDKQRT 300
GPVPVGTKKD PPSAVLSGEG AAPRKEPVVG GTLSPLALAN KAESVVSVTS QCSFSSTIVH 360
VGDKKPPESD IIMMEDLPGL APGPAPSPAP SPTVAPDPAP DAYRPVGLTK AVLSLHTQKE 420
EQAFLSRFRD LGRLRGLDSS STAPSALGER GCHHGPAPPS RRHHCRSKAK RSRHHQSPRA 480
EAPCYVSHPS PVPPSTPWPA PPATTPFPAV VQPYPLPVFS PRGGPQPLPP APTSVPPAAF 540
PTPLVTPMVA LVLPNYLFPT PSSYPYGAPQ TPVEGPPTPA SYSPSPSLPA LPPSPPRRPD 600
SPLFNSRCSS PLQLNLLQLE ELPRAEGAAG AGGPGSSAGP PPPSEEAAEP EARLVEVTES 660
SNQDALSGSS DLLELLLQED SRSGTGSAAS GSLGSGLGSG SGSGSHEGGS TSASITRSSQ 720
SSHTSKYFGS IDSSEAEAGA ARGGAEPGDQ VIKYVLQDPI WLLMANADQR VMMTYQVPSR 780
DMTSVLKQDR ERLRAMQRQQ PRFSEDQRRE LGAVHSWVRK GQLPRALDVM ACVDCGSSTQ 840
DPGHPDDPLF SELDGLGLEP MEEGGGEQGS SGGGSGEGEG CEEARAQGGA KASSFQDLAM 900
EEEKESRSSA SPALPTAGNG TS 922
Nucleotide Sequence
(Fasta)		 ATGTGGATGA AAGGGCTCGC CCCCCTGCTG GGCTACCTGC CCCACGGACC TCCTCGGGGG 60
CCCGACGTGC TCCTGTTCCT GCACCCTGAG GACCGACCCC TCATGCTGGC TATCCACAAG 120
AAGATCCTGC AGTTGGCGGG CCAGCCCTTT GACCACTCCC CCATCCGCTT CTGTGCCCGC 180
AACGGGGAGT ATGTCACCAT GGACACCAGT TGGGCTGGCT TTGTGCATCC CTGGAGCCGC 240
AAGGTAGCCT TCGTGTTGGG CCGCCACAAA GTACGCACGG CCCCGCTGAA TGAGGATGTG 300
TTCACTCCCC CGGCCCCCAG CCCAGCTCCG ACCCTGGACA CTGATATCCA GGAGCTGTCA 360
GAGCAGATCC ACCGGCTACT GCTACAGCCC GTGCACAGCC CCAGCCCCAC AGGACTCTGT 420
GGAGTCGGCC CCGTGACATC CCCAGGCCTT CTCCACAGCC CCGGCTCCTC CAGTGATAGC 480
AACGGGGGTG ATGCAGAGGG GCCTGGGCCT CCTGCGCCAG TGACTTTCCA GCAGATCTGT 540
AAGGATGTGC ATCTGGTGAA GCACCAGGGC CAGCAGCTTT TTATTGAGTC TCGGGCCCGG 600
CCTCAGCCCC GGCCTCGCCT CCCTGCTACA GGCACATTCA AGGCCAGGGC CCTTCCCTGC 660
CAATCCCCAG ACCCAGAGCT GGAGACGGGT TCTGCTCCCA TCCCGGCCCC ACTAGCCTTG 720
GCCCCTGAGG AGGCCGAGAG GAAAGAAGCC TCCAGCTGCT CCTACCAACA GATCAACTGC 780
CTGGACAGCA TCCTCAGGTA TCTGGAGAGC TGCAACCTCC CCAGCACCAC TAAGCGTAAA 840
TGTGCCTCCT CCTCCTCTTA CACCACCTCC TCAGCCTCTG ACGATGACAA GCAGAGGACC 900
GGTCCAGTCC CTGTGGGGAC CAAGAAAGAT CCGCCGTCAG CAGTGCTGTC TGGGGAGGGG 960
GCCGCCCCCC GGAAGGAGCC AGTGGTGGGA GGCACCCTGA GCCCGCTCGC CCTGGCCAAT 1020
AAGGCGGAGA GCGTGGTGTC CGTCACCAGT CAGTGTAGCT TCAGCTCCAC CATCGTCCAT 1080
GTGGGAGACA AGAAGCCCCC GGAGTCGGAC ATCATCATGA TGGAGGACCT GCCTGGCCTA 1140
GCCCCCGGCC CAGCCCCCAG CCCAGCCCCC AGCCCCACAG TAGCCCCTGA CCCAGCCCCA 1200
GATGCCTACC GTCCAGTAGG GCTGACCAAG GCCGTGCTGT CCCTGCACAC ACAGAAGGAA 1260
GAGCAAGCCT TCCTCAGCCG CTTCCGAGAC CTGGGCAGGC TGCGTGGACT CGACAGCTCT 1320
TCCACAGCGC CCTCAGCCCT TGGCGAGCGA GGCTGCCACC ATGGCCCCGC ACCCCCAAGC 1380
CGCCGACACC ACTGCCGATC CAAAGCCAAG CGCTCACGCC ACCACCAGAG CCCTCGGGCT 1440
GAAGCGCCCT GCTATGTCTC ACACCCCTCA CCTGTGCCAC CCTCCACCCC CTGGCCTGCC 1500
CCACCAGCCA CTACCCCCTT CCCAGCAGTT GTCCAGCCCT ACCCTCTCCC AGTGTTCTCC 1560
CCTCGAGGAG GCCCCCAGCC TCTTCCCCCT GCTCCCACAT CTGTGCCCCC GGCTGCTTTC 1620
CCCACTCCTC TGGTGACCCC CATGGTGGCC TTGGTGCTCC CTAACTATCT GTTCCCAACC 1680
CCATCCAGCT ATCCTTACGG GGCACCCCAG ACCCCTGTTG AAGGGCCTCC CACTCCTGCC 1740
TCGTACTCCC CTTCTCCATC CTTGCCCGCC CTCCCCCCAA GCCCTCCTCG CCGCCCGGAC 1800
TCTCCACTGT TCAACTCAAG ATGCAGCTCT CCACTCCAGC TTAATCTGCT GCAGCTCGAG 1860
GAGCTCCCCC GTGCTGAGGG GGCTGCTGGT GCAGGGGGCC CTGGGAGCAG TGCTGGGCCC 1920
CCACCTCCCA GTGAGGAGGC TGCTGAGCCA GAGGCCAGAC TGGTGGAGGT CACTGAGTCC 1980
TCCAATCAGG ACGCACTTTC CGGCTCCAGC GACCTGCTGG AACTGCTGCT GCAAGAGGAC 2040
TCGCGCTCCG GCACAGGCTC CGCAGCCTCA GGCTCCTTGG GCTCTGGCTT GGGCTCTGGG 2100
TCTGGTTCAG GCTCCCATGA AGGGGGCAGC ACCTCAGCCA GCATCACTCG CAGCAGCCAG 2160
AGCAGCCACA CAAGCAAATA CTTTGGCAGC ATCGACTCTT CCGAGGCTGA GGCTGGGGCT 2220
GCTCGGGGCG GGGCTGAGCC GGGGGACCAG GTGATTAAGT ACGTGCTCCA GGATCCCATT 2280
TGGCTGCTCA TGGCCAATGC TGACCAGCGC GTCATGATGA CTTACCAGGT ACCCTCCAGG 2340
GACATGACCT CTGTGCTGAA GCAGGATCGG GAGCGGCTCC GAGCCATGCA GAGGCAGCAG 2400
CCCCGGTTTT CTGAGGACCA GCGGCGGGAA CTGGGCGCTG TGCACTCCTG GGTCCGCAAG 2460
GGCCAACTGC CTCGGGCTCT TGATGTGATG GCCTGTGTGG ACTGTGGGAG CAGCACCCAA 2520
GATCCTGGTC ACCCTGATGA CCCACTGTTC TCAGAGCTGG ATGGACTGGG GCTGGAGCCC 2580
ATGGAAGAGG GTGGAGGCGA GCAGGGCAGC AGCGGTGGCG GCAGTGGTGA GGGTGAGGGC 2640
TGCGAGGAGG CCCGGGCCCA AGGTGGGGCC AAGGCCTCAA GCTTTCAGGA CTTGGCCATG 2700
GAGGAGGAGA AAGAAAGCAG GAGCTCAGCC AGTCCAGCCT TACCTACAGC AGGAAACGGC 2760
ACGAGCTAGA CTCCATTCTG GGACCATCTC CAGGAGTCCA CAAGATGCTT TCTTCTCCTA 2820
TGTCCCAATT CTCAGAACTC AGATGTGGCT GGACCAACCA GTGGGAAACT GCCCCAGCTT 2880
CTCCCACCAT AGGGGGCCGG ACCCCCATCA CCAGCCCAGG ATCCAGGGGC TGCCTCTGGC 2940
CTCGTAGGGA GCGGAGAGCA GAACTCCGCA GCCCAGCCCA GCCCAGAGGA GTGTCACCTC 3000
CCGCCTTTGG AGAGGAATCC TTCCCTCCCC TGGACAGAGT TGCTGACAGG CTGCTTAAGT 3060
GGCCTCTCCA TATCCTAGCT GAGCCTGAAT CCGACTCCTG AGGGTTGGGG CTGCACTTAT 3120
TTATCGGGGG AGACAGCTGT CTCTCCCACC TCCTCCCCAC ATGGGAGGAG AGCCTGAGGC 3180
CCAAGCAGGA CCTGGGGGAT CCAGCCCCTA GCTGCTCGGG GGTGGGGGAG GTTGGTGGAC 3240
CATGGAGTCC CTGGTGCTGC CCCTCAGGTG GGACCCAGGT GTTCTCAGCT GTACCCTCTG 3300
CCGATGGCAT TTGTGTTTTT GATATTTGTG TCTGTTACTA CTTTTTTAAT ACAAAAAGAT 3360
AAAAACGGCC AGGACTTTGT GGAATGAAGT TTGGGGTTGG GGTGAGGGGA GCACGTCTAG 3420
GAGGGACTCG GCCCTGCTTC CGGGAAGGTT GTAGTGAGGG TGCACAGGGC CATCCCCTGA 3480
AGACCCCCAT TCCTCTTTCC CCCAATCCTG TCCAGGTGAG GGCCCTGCTC AGCCTACTAC 3540
ATCCACGCCC AGCTGTGACT CTGCTGTCCC CTCTAGCATG GCCTCAGCTG GGTTTACCCT 3600
GGGAAGGAGA GATGAGAGGC ACGTGTGGCC AAGGGCTTGG GTGAGCTCCA GCCCAGGTCA 3660
CAAGTGGCCG AGGCAGAGGA AGCCCGCTTA ACCCCGTCGT GCCTTGAGGT ATTCGAGGGT 3720
GTTTGTCTTC CTTGGCTTCC TTTTTTAAAT AAAAAAAGAC GAAATTTCAC TCTGTTACCC 3780
AGCTGGAGTG CAATGACGCC ATCTCGGCTC ACTGCAACCT GCGCCTCCTG GGTTCAAGCG 3840
ATTCTCCTGC CTCGGCCTCC CGAGTAGCTG GGATTATAGT GTCCACCACC ATCTCCGGCT 3900
AATTTTGTAT TTTTAGTACA AATTAGAGAT GGGGTTTCAC CATTGTTCAG TCTGGTCGCA 3960
AACTCCTGAC CTCAGGTGAT CTGCCCGCCT CGGCCTCGCA AAGTGCTGGG GTTACAGGCG 4020
TGAGCCACCT TGCCTGGCCT TCCTTGGCTT CTTGGTCACT GCACAGAGAG GTCAGTCTAG 4080
GTAGCTAAGG GACACATGGA GTCATGTGCT CACTCATGGT TGAATTGGCC CCAAAAGGTT 4140
TGGAAGAATG GAGGAGCAAA GCATTAACTC TCTGGCTCAG AACCTGAAAA GGAAGAGGTA 4200
GCTTAGGAAG GGATGAGTCG CTGAAGAACC ACTGCAGACA CTTATTTACT GATTATCACT 4260
TACTGTCACC CGCTCACAGT TGATTTTTTT TTTTTTTTTT TTTTTTTTTT TTTTTGAGAC 4320
AGAGTCTCGC TTAGTCGCCC AGGCTGGAGT GCAGTGGCGC GATCTCGGCT CACTGCAAGC 4380
TCCGCCTCCC GGGTTCACGC CATTCTCCTG CCTCAGCCTC CCGAGTAGCT GGGACTACAG 4440
GCGCCCGCCG CCTCGCCCGG CTAATTTTTT GCATTTTTAG TAGAGACGGG GTTTCACCAT 4500
GTTAGCCAGG ATGGTCTCGA TCTCCTGACC TCGTGATCCG CCCGCCTCGG CCTCCCAAAG 4560
TGCTGGGATT ACAGGCGTGA GCCACCGCGC CCGGCCAGTT GATTTATTTT GAGGCACATC 4620
TACTTTATCC CGGCGCTGTG GCTTAGCTGG TTAAAGCGCC TGTCTAGTAA ACAGGAGATC 4680
CTGGGTTCGA ATCCCAGCGG TGCCTGAGTT GGTGGGGAGT GATATATTAT TGCTGCAAGT 4740
GCACTTCTCC ACTTTCAAAG TGCGTTTCTG TGTGGTTTTA AGAAAGATTC TTCTTACAAG 4800
CCAATCCGTC TTTGGGCCTC CGTTCCCCTG CACTTTTAGT GTGTTTTGGA AGCTACAGAT 4860
TCTCACTTCG CTTTCATGAA GTAGCACGAA GTAGGCATCT CAGGGTCTGT CCTCAAGGGT 4920
ATGGAAGACA GGGCTCGGAT TTGGGCCCGT TTTGTTTCCA TCCTATGCTC GGGTAGGAGA 4980
GGGAGAATGG GAAAGCTGCC ACTCCAGCGG GGCCGCTGAC GGCTGCTGGG GAGAAGGCAT 5040
GGTCTGCGCC ACCGAGCCGA GGCGCACTAG CGCTGGCGTC TCGAGGCAGC GTGGGTGGAG 5100
CCGGCTGGAG GCGGGCGTGT TGATAGGCAG CTATAGTTGC GCAGGGGCGA GCCCGCACGC 5160
GGCTGTGATG GCCGAGTGGT TAAGGCGTTG GACTCGAAAT CCAATGGGGT CTCCCCGCGC 5220
AGGTTCGAAT CCTGCTCACA GCGTCAGTAC TTTTGGTAAT AGGTATCTCG GTCTCTGGAG 5280
AAGGAAAAAG CAGTTTGTTT TCTAGTTCTT TCCTTGGAGA ATCTCCCGCG TTATTTTGAG 5340
AATCTCAGGG ACTCGGCCGT CAGGGTCCAG CCCGCGAGCG CCCTCTTGCG AGTCTCATAC 5400
TCCTGTCGAC CTGCAAAAGC CTTTTTACTG CCGATTTCAC TTCCTAACGC CACCACGCTC 5460
AGGTGGCTCC TTAGGGCTAC TCAGCAATCG TTACTTCCCC CCAATTCATT CACTCTCCTA 5520
CTCTCCTATG CGACTGCTTC AT 5542
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus57.3 0.00e+00 932.9
CGD-HoS-021038Homo sapiens (Human)60.26 0.00e+00 1007.7
CGD-MuM-021794Mus musculus (Mouse)56.32 0.00e+00 929.5
CGD-OvA-022197Ovis aries55.28 0.00e+00 889.4
CGD-RaN-021793Rattus norvegicus57.75 0.00e+00 890.6
Gene Ontology

GO:0005515--protein binding
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0032922--circadian regulation of gene expression
GO:0051591--response to cAMP
GO:0007623--circadian rhythm
GO:0019900--kinase binding
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0043966--histone H3 acetylation
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0043967--histone H4 acetylation
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm