CGDB Gene Information

Tag Content
CGDB ID CGD-AnC-055229
Ensembl Accession ENSACAP00000004695.3
Protein Name PER1
Ensembl Information ENSACAG00000004715; ENSACAT00000004802
Organism Anolis carolinensis
NCBI Taxa ID 28377
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
ZT 12 ZT 0 LD >10 Predicted from orthologs Q65ZG8
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MTTGCEPGQG PFEGGGGNGG CTSGAPRRTR PQRGSEAQGQ ANDDMDINSN GSSGNESHGD 60
SHSSSHSSGN GKDSALLETT ESNKSSNSQS PSPPSSSIAY SLLSASSEQD NPSTSGCSSE 120
QSARVKAQKE LMKALKEMKI RLPSEKRSKG KSGTLATLQY ALSCVKQVQA SQDYYQQWTI 180
DDSHPCNLDM SSYTIEELEN ITSEYTLKNP DTFSVAVSFI TGKIVYISDQ AGFILRCKKD 240
VFKGAKFAEF LAPQDVSIFY GSTAPYHLPS WSACTSSTAG VMDYTQEKSV FCRISGGYES 300
GCELRYYPFR LTPYLTKVCD SDSTEGRPCC LLIAERIHSG YEAPRIPPDK RIFTTRHTPS 360
CLFQDVDERA APLLGYLPQD LIGTPVLFYV HPEDRPLMLA IHKKILQYGG QPFDHSPIRF 420
CARNGEYVTI DTSWSSFVNP WSRKVSFIMG RHKVRTGPLN EDVFTAPKVP KAKPMETDIQ 480
ELSEQIHRSL LQPVHSNGST GLCSIGSNAS HEQFLSIASS SDSNGIPNEE AQAIRPMTFQ 540
EICKDVHMVK NQGQQVFIES QVKPQPHKHS RQALEVPVNR SSQPMETPRD LERRPATSEE 600
SVRKESSNYS YQQINCLDGI IRYLESCNIP SRVKRKCGSS SYTTSSTSDD DKQKVGEEVA 660
CHSKDAPEEM LPTPESQSKR EEPGTAAAAV VGGPLTPLAL PSKAESVVSV TSQCSFSSTI 720
VHVGDKKPPE SDIVMMEEAA PSATPPAPPP NVTPDREQQY RKVGLTKEVL SIHTQKEEQA 780
FLTRFKDLSQ VHVFNSSLGL SSQGQAHPGP HANRGKHSMP FNIEQRQDKH RLRAGLELII 840
SCTSSVPPAP PPGAPSGNSQ NSLPTMPYPT VMPTYPIPVF PPRPAAPSAA EPIQNALPAP 900
QFPTPLVTPM VALVLPNYVF PQMNSPLPQS YFPGGPVFPF APQPVGSTAT PGPDVGAQGL 960
SRSSTPHSVS QPERPESPLF ESRCSSPLQL NLLQMEEMPK TGPMGAPTDW AGVSSGQGLT 1020
NELSTQKEAC MVETHDSSNN DALSSSSDLL DLLLQEDSRS GTGSAASGSG SAASGSMGSG 1080
SNGGSTSASG TTSSKSSNTS KYFGSIDSSE NDLRGKKRTE VEDNEHFIKY VLQDPIWLLM 1140
ANTDDKVMMT YQLPTRDMEA VLKEDREKLK QMQKRQPRFT EEQKKELGEV H 1191
Nucleotide Sequence
(Fasta)		 ATGCAGTCGG CCTCGCACTC CCTCATTGGC CCAGCCACTG GCCAATGAGG GCTTCCCAGG 60
GACAGTGGCA GCACCACGGT ACACGTGCGA GTGGGGCGTG CAACAGGGGG TTGCTGACAT 120
CACCGGGCGC ACTTGGCCAG GGCTGCTCCG CCTCCTACTT ATACAATGCG CCCCGCTTCC 180
TTGTTAAGAG CCAGATGCAC TTCCAGAGGG AAGGCTAACC TGAGCCTGCC TGTCCGCAGC 240
ACCTTGCTTT GCTCTTTCCA GGAGGATGTA TTGGGTCAGA AGCAGCAACA GAGTCTCCAC 300
TGGCTGGTCT AGGAGAAGCG GAGGCCAGTT CTCCCCGTCC CAGGCTTGTG TGGGCTAAGC 360
CACCTGCACT TCTCCTGGTG TTTCCTAAGC TGTCTTTCTT CTTTGACCGA ACCTCTGTTT 420
GGATAACGCA AGCTAAACTG AAGTACGATT CGGGTTCGCC CAAAAAGTTT TCTTCTTCAG 480
CAGCTGGTGA AACCCCAACC TTTCCCCTGC AATTCCCTCC GTTTCCTTGA AGAGACCCCC 540
ATGCCCTAAA ACTTATCATG ACGACTGGCT GTGAGCCTGG GCAAGGCCCC TTTGAGGGCG 600
GTGGAGGCAA TGGAGGATGT ACTTCTGGAG CCCCCCGGAG AACCAGGCCC CAGCGAGGGA 660
GCGAAGCCCA AGGCCAAGCC AACGATGACA TGGACATCAA CAGCAACGGC TCCAGTGGCA 720
ATGAGTCCCA TGGTGACTCC CACAGCAGTT CTCACAGCAG CGGTAATGGC AAAGACTCAG 780
CCCTGCTGGA AACCACTGAA AGCAACAAGA GCTCCAATTC CCAAAGCCCA TCTCCTCCCA 840
GCAGCTCCAT TGCCTACAGC CTTCTTAGTG CAAGCTCTGA GCAGGACAAC CCATCAACCA 900
GTGGTTGCAG CAGTGAGCAG TCTGCACGGG TGAAGGCCCA GAAGGAACTC ATGAAGGCCC 960
TGAAGGAGAT GAAGATCCGG CTGCCCTCTG AGAAACGCAG CAAGGGGAAG TCAGGGACTC 1020
TGGCCACTCT GCAGTATGCT CTCTCTTGTG TAAAACAAGT CCAAGCGAGC CAGGATTACT 1080
ATCAGCAATG GACCATTGAT GACAGTCATC CTTGCAATCT GGACATGTCT TCTTACACTA 1140
TCGAGGAGCT AGAAAACATC ACTTCAGAGT ACACTCTCAA AAACCCTGAT ACCTTTTCCG 1200
TGGCTGTCTC TTTCATCACG GGGAAAATTG TCTACATCTC GGACCAGGCA GGCTTCATCC 1260
TCCGCTGCAA GAAAGATGTC TTCAAGGGGG CAAAGTTTGC CGAGTTCCTG GCGCCACAAG 1320
ATGTCAGCAT CTTCTATGGA TCCACTGCGC CATACCACTT GCCCTCCTGG AGCGCCTGCA 1380
CTTCTTCCAC TGCTGGTGTA ATGGATTACA CCCAGGAGAA ATCCGTCTTC TGTCGTATCA 1440
GCGGAGGTTA CGAGAGTGGA TGCGAGCTGC GCTACTACCC TTTCCGGCTC ACCCCGTACC 1500
TGACCAAAGT GTGCGACTCC GACAGCACCG AGGGACGACC GTGCTGTTTG CTCATCGCAG 1560
AGCGCATCCA TTCAGGCTAC GAAGCTCCCA GAATTCCTCC CGATAAGAGA ATCTTCACCA 1620
CCAGACACAC CCCCAGTTGC CTATTTCAGG ATGTGGATGA GCGAGCTGCT CCTCTGCTAG 1680
GCTACCTTCC TCAGGACCTG ATTGGAACCC CTGTCCTTTT CTACGTACAT CCTGAGGATC 1740
GGCCTCTCAT GCTGGCCATA CACAAAAAGA TTTTGCAGTA TGGCGGCCAA CCCTTTGATC 1800
ACTCACCCAT CCGCTTCTGC GCCCGCAATG GCGAATACGT CACCATTGAC ACCAGCTGGT 1860
CCAGCTTTGT CAACCCCTGG AGCCGCAAAG TCTCTTTCAT TATGGGGAGG CATAAAGTGC 1920
GGACGGGTCC CCTCAATGAG GATGTCTTCA CAGCCCCCAA GGTCCCGAAG GCAAAGCCTA 1980
TGGAAACAGA CATCCAGGAA CTTTCAGAGC AGATCCACCG TTCCCTGCTA CAGCCAGTAC 2040
ACAGCAATGG GTCCACTGGC CTTTGTAGCA TTGGCAGCAA TGCTTCCCAT GAGCAGTTCC 2100
TAAGCATCGC CTCATCTAGC GACAGCAATG GCATCCCCAA CGAGGAGGCG CAAGCTATTC 2160
GGCCGATGAC TTTCCAGGAG ATCTGCAAAG ATGTGCACAT GGTGAAGAAC CAGGGCCAGC 2220
AGGTTTTCAT TGAATCCCAA GTCAAGCCCC AGCCCCACAA ACATTCCCGA CAAGCTCTGG 2280
AAGTGCCAGT CAATCGCAGC AGCCAGCCCA TGGAGACCCC AAGGGACCTG GAGAGGAGGC 2340
CAGCTACCTC TGAGGAGTCA GTGAGGAAAG AATCCTCCAA CTATTCCTAC CAGCAGATCA 2400
ACTGCCTAGA TGGCATCATC AGATACCTAG AGAGCTGCAA TATTCCAAGC CGCGTGAAGC 2460
GGAAATGTGG CTCCTCCTCG TACACCACAT CCTCAACATC AGATGATGAC AAGCAAAAAG 2520
TTGGTGAAGA AGTGGCCTGT CACAGCAAAG ATGCACCAGA GGAAATGCTA CCGACCCCGG 2580
AGAGCCAGTC CAAGAGGGAA GAGCCCGGGA CGGCAGCAGC TGCCGTGGTG GGAGGCCCAC 2640
TGACTCCGCT GGCCTTGCCT AGCAAAGCCG AGAGCGTGGT CTCCGTGACC AGTCAGTGTA 2700
GCTTCAGCAG TACCATCGTC CACGTGGGAG ACAAGAAACC TCCCGAGTCG GATATCGTCA 2760
TGATGGAGGA GGCGGCACCC AGCGCGACCC CTCCGGCCCC CCCACCGAAC GTGACCCCAG 2820
ACCGGGAGCA GCAGTACCGC AAGGTGGGGC TGACCAAAGA GGTCCTCTCC ATCCACACTC 2880
AGAAGGAGGA ACAGGCCTTC CTCACCCGCT TCAAGGACCT CAGCCAGGTC CACGTCTTTA 2940
ACTCGTCCTT GGGACTCAGC TCACAGGGGC AGGCTCACCC TGGACCCCAT GCCAACCGAG 3000
GCAAACATTC AATGCCTTTT AACATAGAAC AAAGACAAGA CAAACATAGG CTCCGAGCGG 3060
GCCTTGAACT CATAATCTCC TGCACCTCCT CTGTGCCCCC GGCTCCACCT CCTGGGGCTC 3120
CCTCTGGCAA CTCCCAAAAC AGCCTCCCCA CCATGCCTTA CCCGACCGTC ATGCCCACCT 3180
ACCCGATTCC GGTCTTTCCC CCTCGACCCG CCGCTCCCTC GGCCGCGGAG CCCATCCAGA 3240
ACGCTTTGCC TGCCCCCCAG TTCCCCACCC CTCTGGTCAC CCCCATGGTG GCCTTAGTCC 3300
TGCCGAACTA TGTTTTCCCT CAGATGAACA GCCCTCTCCC CCAGTCCTAC TTCCCTGGCG 3360
GCCCTGTTTT CCCTTTCGCC CCACAGCCGG TTGGGAGCAC AGCTACTCCT GGGCCCGATG 3420
TGGGTGCACA GGGCCTGTCG CGCTCCTCCA CCCCGCACTC GGTGAGCCAG CCTGAGCGGC 3480
CCGAGTCACC CCTCTTTGAG TCGCGCTGCA GCTCCCCTTT GCAGCTGAAC CTGTTGCAGA 3540
TGGAAGAGAT GCCCAAGACA GGGCCGATGG GAGCCCCCAC GGACTGGGCC GGCGTGAGCA 3600
GCGGGCAGGG ACTGACCAAT GAACTCAGCA CCCAGAAAGA AGCATGTATG GTGGAAACAC 3660
ATGATTCCTC CAACAACGAT GCTCTGTCCA GCTCCAGTGA CCTCCTGGAC CTGCTTCTTC 3720
AGGAAGATTC ACGCTCTGGC ACGGGGTCAG CCGCTTCGGG CAGTGGCTCC GCTGCCTCTG 3780
GCTCCATGGG TTCTGGCTCC AATGGCGGTA GCACTTCTGC CAGTGGCACA ACCAGCAGCA 3840
AGAGCAGCAA CACCAGCAAA TACTTTGGCA GCATCGACTC CTCGGAGAAC GACCTACGAG 3900
GCAAGAAGCG CACAGAGGTG GAAGACAATG AACATTTCAT CAAGTACGTC CTGCAAGATC 3960
CCATTTGGCT GCTGATGGCC AACACTGATG ACAAGGTCAT GATGACCTAC CAGCTCCCTA 4020
CCAGGGACAT GGAGGCAGTG TTGAAGGAGG ATCGGGAGAA GCTGAAGCAA ATGCAGAAGC 4080
GGCAGCCCCG GTTCACGGAA GAACAGAAGA AGGAATTGGG CGAAGTGCAT
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-CaE-021686Caenorhabditis elegans24.26 4.70e-16 84.34
CGD-EqC-020994Equus caballus50 0.00e+00 1017.7
CGD-HoS-021038Homo sapiens (Human)49.74 0.00e+00 1023.1
CGD-OvA-022197Ovis aries59.03 0.00e+00 862.4
CGD-RaN-021793Rattus norvegicus60.53 0.00e+00 885.2
Gene Ontology

GO:0004871--signal transducer activity
GO:0007165--signal transduction
GO:0006355--regulation of transcription, DNA-templated
GO:0005515--protein binding
GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation