CGDB Gene Information

Tag Content
CGDB ID CGD-AiM-053758
Ensembl Accession ENSAMEP00000002835.1
Protein Name PER1
Ensembl Information ENSAMEG00000002633; ENSAMET00000002955
Organism Ailuropoda melanoleuca
NCBI Taxa ID 9646
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 GSPSEAWVLG LDLPPHSPSQ AARPPCALVV ASPPSVFSSC PPHGPDMSGP LEEADGGGDP 60
GPGESFCPGG APSPGPPQHR SCPGPGLADD TDANSNGSSG NESNGPESRG ASQRSSHSSS 120
SGNGKDSALL ETTESSKSTN SQSLSPPSSS IAYSLLSASS EQDNPSTSGC SSEQSARART 180
QKELMTALRE LKLRLPPERR GKGRSGTLAT LQYALACVKQ VQANQEYYQQ WSLEEGEPCA 240
LDMSTYTLEE LEHITSEYTL RNQDTFSVAV SFLTGRIVYI SEQAGVLLRC KRDVFRGARF 300
SELLAPQDVG VFYGSTAPSR LPTWGAGTSA GSGVKDFTQE KSIFCRIRGG PDRDSGPRYQ 360
PFRLTPYVTK IRVSDGAPAQ PCCLLIAERI HSGYEAPRIP PDKRIFTTRH TPSCLFQDVD 420
ERAAPLLGYL PQDLLGAPVL LFLHPEDRPL MLAMHEKILQ LAGQPFDHSP IRFCARNGEY 480
VTMDTSWAGF VHPWSRKVAF VLGRHKVRTA PLNEDVFTPP APGPALALDA DIQELSEQIH 540
RLLLQPVHSP SPTGLCGVGP VASPGPLLSP GSSSDSNGGD AEGPGPPAPV TFQQICKDVH 600
LVKHQGQQLF IESRARPPPR PRLPATGTFK AKTLSCQSPD PELETVPAPV QAPLTLAPEE 660
AERKEASGCS YQQINCLDGI LRYLESCNIP GTTKRKCASS SSCTTSSASD DDKQRTGPVV 720
LGARKDPSAV LSGEGATPQK EPVVGGTLSP LALANKAESV VSVTSQCSFS STIVHVGDKK 780
PPESDIIMME DLPGLARPAP SPAPSPTVAP DPAPDAYRPV GLTKAVLSLH TQKEERAFLS 840
RFQDLSRLRA LNGSSPAALA PGCHHGPAPP GRRHHCRSRA KRSRHHQTPR AEAPCYGSPP 900
SSVSPPPPPP PPATTPFPAV VQSYPLPMFS PRGGPQPLPS APTAGPPAAF PAPLVTPMVA 960
LVLPNCLFPS PPSCPCGVAQ TPAGGPPTPT SHSPSPSLPP APPSPXLEEP PRAEGGAVAG 1020
GPGSSAGPPP PSEEAAEPEA RLVEVTESSN QDALSGSSDL LELLLQEDSR SGTGSAASGS 1080
LGSGLGSGSG SRSHEGGSTS ASITRSSQSS HTSKYFGSVD SSEAEAGAAQ ASSEPGDQVI 1140
KCVLQDPIWL LMANADQRVM MTYQVPSRDM ASVLKQDRER LRAMQKQQPR FSEDQRRELG 1200
AVHSWVRKGQ LPRALDVMAC VDCGSSTQDP GHPDDPLFSE LDGLGLEPME EGGGEGGGGG 1260
GEGEGEGADE AQAQAGARVS GSQDLAMEEE EQGGRSSSPA LPATENGTS 1309
Nucleotide Sequence
(Fasta)		 GGATCCCCGT CGGAAGCCTG GGTCCTAGGC TTGGATCTCC CACCTCACTC CCCCAGCCAG 60
GCCGCCCGGC CCCCGTGTGC GCTCGTGGTG GCCTCTCCGC CTTCTGTGTT TTCCTCCTGC 120
CCTCCCCATG GCCCAGACAT GAGTGGCCCC CTAGAAGAGG CTGATGGGGG AGGGGACCCC 180
GGGCCGGGGG AATCCTTCTG CCCTGGAGGG GCCCCATCCC CTGGGCCTCC TCAGCACCGG 240
TCTTGCCCTG GTCCCGGCCT GGCTGATGAC ACAGATGCCA ACAGCAATGG CTCCAGCGGC 300
AATGAATCCA ATGGGCCTGA GTCCCGCGGC GCATCTCAGC GGAGCTCCCA TAGCTCGTCC 360
TCTGGCAACG GCAAGGACTC AGCCCTGCTG GAGACCACTG AGAGCAGCAA GAGTACGAAC 420
TCTCAGAGTC TGTCGCCACC TAGCAGTTCC ATTGCCTACA GCCTCCTGAG TGCCAGCTCG 480
GAGCAGGACA ACCCGTCTAC CAGCGGCTGC AGCAGTGAAC AGTCAGCCCG GGCGAGGACC 540
CAGAAGGAAC TCATGACGGC TCTGCGGGAG CTCAAGCTTC GGCTGCCGCC CGAGCGCCGG 600
GGCAAGGGCC GCTCTGGGAC CCTGGCCACG CTCCAGTACG CTCTGGCCTG TGTCAAGCAG 660
GTGCAGGCCA ACCAAGAGTA CTACCAGCAG TGGAGCCTGG AGGAGGGCGA GCCTTGTGCC 720
CTGGACATGT CCACCTACAC CCTGGAGGAG CTGGAGCACA TCACGTCCGA ATATACGCTG 780
CGCAACCAGG ACACCTTCTC CGTGGCTGTC TCCTTCCTGA CAGGCCGCAT CGTCTACATT 840
TCGGAGCAGG CGGGTGTCTT GCTGCGCTGC AAACGGGATG TGTTCCGGGG CGCCCGCTTC 900
TCGGAGCTTC TGGCTCCGCA GGATGTGGGC GTCTTCTATG GTTCCACTGC CCCGTCTCGC 960
CTGCCCACCT GGGGCGCTGG GACCTCAGCA GGTTCAGGCG TCAAGGACTT CACCCAGGAG 1020
AAGTCTATCT TCTGCCGTAT CAGAGGAGGT CCTGACCGGG ATTCAGGGCC TCGGTACCAG 1080
CCATTCCGCC TCACGCCATA CGTGACCAAG ATCCGGGTCT CCGATGGAGC CCCAGCACAG 1140
CCGTGTTGCC TTCTCATCGC AGAGCGCATC CACTCGGGTT ACGAAGCTCC CCGGATCCCC 1200
CCCGACAAGA GGATCTTTAC CACGCGGCAC ACACCCAGCT GCCTCTTCCA AGACGTGGAC 1260
GAAAGGGCCG CCCCGCTGCT GGGCTACCTG CCCCAGGATC TCCTGGGGGC CCCAGTGCTC 1320
CTGTTCCTGC ATCCTGAGGA CCGGCCCCTC ATGCTGGCCA TGCACGAGAA GATCCTGCAG 1380
TTGGCCGGTC AGCCCTTTGA CCACTCCCCT ATCCGCTTCT GCGCCCGGAA TGGGGAGTAT 1440
GTCACCATGG ACACCAGCTG GGCCGGCTTC GTGCACCCCT GGAGCCGCAA GGTGGCCTTT 1500
GTCTTGGGCC GCCACAAAGT ACGCACGGCA CCTCTGAATG AGGACGTGTT TACTCCGCCG 1560
GCCCCTGGCC CGGCTCTGGC TCTGGACGCT GACATCCAGG AGCTCTCAGA GCAGATACAC 1620
CGGCTGCTGT TACAGCCCGT GCATAGCCCC AGTCCCACGG GGCTCTGTGG AGTGGGCCCC 1680
GTCGCTTCCC CAGGCCCTCT CCTCAGTCCT GGCTCCTCCA GTGACAGCAA CGGGGGTGAT 1740
GCCGAGGGGC CTGGGCCTCC CGCGCCGGTG ACGTTCCAGC AGATCTGTAA GGATGTGCAC 1800
CTGGTGAAGC ACCAGGGGCA GCAGCTTTTC ATTGAGTCCC GCGCCCGGCC TCCGCCCCGG 1860
CCCCGCCTCC CCGCTACAGG CACATTCAAG GCCAAGACCC TTTCCTGCCA GTCCCCAGAC 1920
CCAGAACTGG AAACGGTCCC TGCTCCCGTC CAGGCCCCGC TCACCTTGGC CCCTGAGGAG 1980
GCTGAGAGGA AAGAGGCCTC CGGTTGTTCC TACCAGCAGA TCAACTGCCT GGACGGCATC 2040
CTCAGGTACC TGGAAAGCTG CAACATCCCC GGCACGACCA AGCGGAAGTG TGCGTCCTCG 2100
TCCTCCTGCA CCACCTCCTC GGCCTCCGAC GACGACAAGC AGAGGACCGG CCCGGTCGTT 2160
CTGGGGGCCA GGAAAGATCC ATCGGCGGTG CTGTCTGGGG AGGGGGCCAC CCCACAGAAG 2220
GAGCCAGTGG TAGGAGGCAC CCTGAGCCCG CTCGCCCTGG CCAATAAGGC AGAGAGCGTG 2280
GTGTCCGTCA CCAGCCAGTG TAGCTTCAGC TCCACCATCG TCCATGTGGG AGACAAGAAG 2340
CCCCCGGAGT CGGACATCAT CATGATGGAG GACCTGCCTG GCCTGGCTCG CCCAGCCCCC 2400
AGCCCAGCCC CCAGCCCCAC GGTAGCCCCC GACCCAGCCC CAGATGCCTA CCGCCCAGTG 2460
GGCCTGACCA AGGCCGTGCT GTCCCTGCAC ACACAGAAGG AGGAGCGGGC CTTCCTCAGC 2520
CGCTTCCAAG ACCTCAGCCG ACTGCGGGCG CTCAATGGCT CCTCCCCGGC CGCCCTGGCC 2580
CCTGGCTGCC ACCACGGCCC CGCACCCCCT GGTCGTCGAC ACCACTGCCG ATCCAGAGCC 2640
AAGCGCTCCC GCCACCACCA GACCCCCCGG GCTGAAGCCC CCTGCTATGG CTCCCCCCCG 2700
TCGTCTGTGT CACCCCCCCC CCCCCCCCCC CCCCCAGCCA CTACTCCCTT CCCAGCTGTG 2760
GTCCAGTCCT ACCCTCTCCC AATGTTCTCC CCACGAGGAG GCCCCCAGCC TCTTCCCTCT 2820
GCCCCCACAG CTGGGCCGCC TGCAGCTTTC CCTGCCCCGC TGGTGACCCC CATGGTAGCC 2880
TTGGTGCTCC CCAACTGTCT GTTCCCCAGC CCACCCAGCT GTCCCTGTGG GGTAGCCCAG 2940
ACCCCTGCCG GAGGGCCTCC AACTCCCACC TCCCACTCCC CTTCCCCGTC CCTGCCCCCA 3000
GCGCCCCCCA GCCCTNAGCT CGAGGAGCCC CCCCGTGCTG AAGGGGGTGC TGTTGCAGGG 3060
GGCCCTGGGA GCAGTGCTGG GCCCCCGCCT CCCAGTGAGG AGGCCGCTGA GCCAGAGGCC 3120
AGACTGGTGG AGGTGACTGA GTCCTCCAAC CAGGACGCGC TGTCGGGCTC CAGCGACCTG 3180
CTGGAGTTGC TGCTTCAGGA GGACTCTCGG TCAGGCACGG GCTCCGCTGC CTCAGGCTCC 3240
CTGGGCTCTG GCCTGGGCTC TGGGTCTGGG TCACGCTCCC ACGAGGGAGG CAGCACCTCG 3300
GCCAGCATCA CACGCAGTAG TCAGAGCAGC CACACGAGCA AGTACTTTGG CAGCGTCGAC 3360
TCTTCCGAGG CCGAAGCCGG GGCTGCCCAG GCCAGCTCTG AGCCTGGGGA CCAAGTCATT 3420
AAGTGCGTGC TCCAGGACCC CATCTGGCTC CTCATGGCCA ACGCCGACCA GCGTGTCATG 3480
ATGACCTACC AGGTGCCGTC CAGGGACATG GCCTCTGTGC TGAAGCAGGA CCGGGAGCGG 3540
CTGCGGGCCA TGCAGAAGCA GCAGCCTCGG TTCTCAGAGG ACCAGCGCAG GGAACTGGGT 3600
GCTGTGCACT CCTGGGTCCG GAAGGGTCAG CTGCCTCGGG CCCTCGATGT GATGGCCTGT 3660
GTGGATTGCG GTAGTAGCAC CCAGGACCCC GGCCACCCGG ATGACCCCCT CTTCTCGGAA 3720
CTGGATGGAC TGGGACTGGA GCCTATGGAG GAGGGCGGAG GCGAGGGTGG GGGCGGGGGT 3780
GGTGAGGGTG AGGGTGAGGG CGCAGACGAG GCCCAGGCTC AAGCTGGGGC CAGGGTCTCC 3840
GGCTCTCAGG ACCTGGCCAT GGAGGAAGAG GAACAAGGTG GGCGCTCATC CAGTCCAGCC 3900
TTACCTGCTA CGGAAAATGG CACCAGCTAG
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus67.01 0.00e+00 1220.7
CGD-GaM-021007Gadus morhua55.48 0.00e+00 642.1
CGD-HoS-021038Homo sapiens (Human)68.26 0.00e+00 1200.3
CGD-OvA-022197Ovis aries67.03 0.00e+00 1165.2
CGD-RaN-021793Rattus norvegicus68.74 0.00e+00 1191.4
Gene Ontology

GO:0005515--protein binding
GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation