CGDB Gene Information

Tag Content
CGDB ID CGD-PaT-040966
Ensembl Accession ENSPTRP00000014870.4
Protein Name PER1
Ensembl Information ENSPTRG00000008726; ENSPTRT00000016072
Organism Pan troglodytes
NCBI Taxa ID 9598
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:VGNC Symbol;Acc:VGNC:9508](View all)
Protein Sequence
(Fasta)		 MSGPLEGADG GGDPRPGESF CPGGVPSPGP PQHRPCPGPS LADDTDANSN GSSGNESNGH 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCSMDMSTY TLEELEHITS EYTLQNQDTF SVAVSFLTGR IVYISEQAAV 240
LLRCKRDVFR GTRFSELLAP QDVGVFYGST APSRLPTWGT GASAGSGLRD FTQEKSVFCR 300
IRGGPDRDPG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAP 480
SLDTDIQELS EQIHRLLLQP VHSPSPTGLC GVRPVTSPGP LHSPGSSSDS NGGDAEGPGP 540
PAPVTFQQIC KDVHLVKHQG QQLFIESRAR PQSGPRLCQS PDPELEAGSA PVQAPLALVP 600
EEAERKEASS CSYQQINCLD SILRYLESCN LPSTTKRKCA SSSSYTTSSA SDDDRQRTGP 660
VSVGTKKDPP SAVLSGEGAT PRKEPVVGGT LSPLALANKA ESVVSVTSQC SFSSTIVHVG 720
DKKPPESDII MMEDLPGLAP GPAPSPAPSP TVAPDPAPDA YRPVGLTKAV LSLHTQKEEQ 780
AFLSRFRDLG RLRGLDSSST APSALGERGC HHGPAPPSRR HHCRSKAKRS RHHQNPRAEA 840
PCYVSHPSPV PPSTPWPTPP ATTPFPAVVQ PYPLPVFSPR GGPQPLPPAP TSVPPAAFPA 900
PLVTPMVALV LPNYLFPTPS SYPYGALQTP AEGPPTPASH SPSPSLPALP PSPPHRPDSP 960
LFNSRCSSPL QLNLLQLEEL PRAEGAAVAG GPGSSAGPPP PSAEAAEPEA RLAEVTESSN 1020
QDALSGSSDL LELLLQEDSR SGTGSAASGS LGSGLGSGSG SGSHEGGSTS ASITRSSQSS 1080
HTSKYFGSID SSEAEAGAAR GGAEPGDQVI KYVLQDPIWL LMANADQRVM MTYQVPSRDM 1140
TSVLKQDRER LRAMQKQQPR FSEDQRRELG AVHSWVRKGQ LPRALDVMAC VDCGSSTQDP 1200
GHPDDPLFSE LDGLGLEPME EGGGEQGSSG GGSGEGEGCE EAQGGAKASS SQDLAMEEEE 1260
EGRSSSSPAL PTAGNCTS 1278
Nucleotide Sequence
(Fasta)		 ATGAGTGGCC CCCTAGAAGG GGCTGATGGG GGAGGGGACC CCAGGCCTGG GGAATCATTT 60
TGTCCTGGGG GCGTCCCATC CCCTGGGCCC CCACAGCACC GGCCTTGCCC AGGCCCCAGC 120
CTGGCCGATG ACACCGATGC CAACAGCAAT GGTTCAAGCG GCAATGAGTC CAACGGGCAT 180
GAGTCTAGAG GCGCATCTCA GCGGAGCTCA CACAGCTCCT CCTCAGGCAA CGGCAAGGAC 240
TCAGCCCTGC TGGAGACCAC TGAGAGCAGC AAGAGCACAA ACTCTCAGAG CCCATCCCCA 300
CCCAGCAGTT CCATTGCCTA CAGCCTCCTG AGTGCCAGCT CAGAGCAGGA CAACCCGTCC 360
ACCAGTGGCT GCAGCAGTGA ACAGTCAGCC CGGGCAAGGA CTCAGAAGGA ACTCATGACA 420
GCACTTCGAG AGCTCAAGCT TCGACTGCCG CCAGAGCGCC GGGGCAAGGG CCGCTCTGGG 480
ACCCTGGCCA CGCTGCAGTA CGCACTGGCC TGTGTCAAGC AGGTGCAGGC CAACCAGGAA 540
TACTACCAGC AGTGGAGCCT GGAGGAGGGT GAGCCTTGCT CCATGGATAT GTCCACCTAT 600
ACCCTGGAGG AGCTGGAGCA CATCACGTCT GAGTACACAC TTCAGAACCA GGATACCTTC 660
TCAGTGGCTG TCTCCTTCCT GACGGGCCGA ATCGTCTACA TTTCGGAGCA GGCAGCTGTC 720
CTGCTGCGTT GCAAGCGGGA CGTGTTCAGG GGTACCCGCT TCTCTGAGCT CCTGGCTCCC 780
CAGGATGTGG GAGTCTTCTA TGGTTCCACT GCTCCATCTC GCCTGCCCAC CTGGGGCACA 840
GGGGCCTCAG CAGGTTCAGG CCTCAGGGAC TTTACCCAGG AGAAGTCCGT CTTCTGCCGT 900
ATCAGAGGAG GTCCTGACCG GGATCCAGGG CCTCGGTACC AGCCATTCCG CCTAACCCCA 960
TATGTGACCA AGATCCGGGT CTCAGATGGG GCCCCTGCAC AGCCGTGCTG CCTGCTGATT 1020
GCAGAGCGCA TCCATTCGGG TTACGAAGCT CCCCGGATAC CCCCTGACAA GAGGATTTTC 1080
ACTACGCGGC ACACACCCAG CTGCCTCTTC CAGGATGTGG ATGAAAGGGC TGCCCCCCTG 1140
CTGGGCTACC TGCCCCAGGA CCTCCTGGGG GCCCCAGTGC TCCTGTTCCT GCATCCTGAG 1200
GACCGACCCC TCATGCTGGC TATCCACAAG AAGATCCTGC AGTTGGCGGG CCAGCCCTTT 1260
GACCACTCCC CTATCCGCTT CTGTGCCCGC AACGGGGAGT ATGTCACCAT GGACACCAGC 1320
TGGGCTGGCT TTGTGCACCC CTGGAGCCGC AAGGTAGCCT TCGTGTTGGG CCGCCACAAA 1380
GTACGCACGG CCCCCCTGAA TGAGGACGTG TTCACTCCCC CGGCCCCCAG CCCAGCTCCC 1440
TCCCTGGACA CTGATATCCA GGAGCTATCA GAGCAGATCC ACCGGCTGCT GCTGCAGCCC 1500
GTCCACAGCC CCAGCCCCAC AGGACTCTGT GGAGTCCGCC CTGTGACATC CCCAGGCCCT 1560
CTCCACAGCC CTGGGTCCTC CAGTGATAGC AACGGGGGTG ATGCAGAGGG GCCTGGGCCT 1620
CCTGCGCCAG TGACTTTCCA GCAGATCTGT AAGGATGTGC ATCTGGTGAA GCACCAGGGC 1680
CAGCAGCTTT TTATTGAGTC TCGGGCCCGG CCTCAGTCCG GGCCCCGCCT CTGCCAATCC 1740
CCAGACCCAG AGCTGGAGGC GGGTTCTGCT CCCGTCCAGG CCCCACTAGC CTTGGTCCCT 1800
GAGGAGGCCG AGAGGAAAGA AGCCTCCAGC TGCTCCTACC AACAGATCAA CTGCCTGGAC 1860
AGCATCCTCA GGTACCTGGA GAGCTGCAAC CTCCCCAGCA CCACTAAGCG TAAATGTGCC 1920
TCCTCCTCCT CCTATACCAC CTCCTCAGCC TCTGACGACG ACAGGCAGAG GACAGGTCCA 1980
GTCTCTGTGG GGACCAAGAA AGATCCGCCG TCAGCAGTGC TGTCTGGGGA GGGGGCCACC 2040
CCACGGAAGG AGCCAGTGGT GGGAGGCACC CTGAGCCCGC TCGCCCTGGC CAATAAGGCG 2100
GAGAGCGTGG TGTCCGTCAC CAGTCAGTGT AGCTTCAGCT CCACCATCGT CCATGTGGGA 2160
GACAAGAAGC CCCCGGAGTC GGACATCATC ATGATGGAGG ACCTGCCTGG CCTAGCCCCA 2220
GGCCCAGCCC CCAGCCCAGC CCCCAGCCCC ACAGTAGCCC CTGACCCAGC CCCAGACGCC 2280
TACCGTCCAG TGGGGCTGAC CAAGGCCGTG CTGTCCCTGC ACACACAGAA GGAAGAGCAA 2340
GCCTTCCTCA GCCGCTTCCG AGACCTGGGC AGGCTGCGTG GACTCGACAG CTCTTCCACA 2400
GCTCCCTCAG CCCTTGGCGA GCGAGGCTGC CACCACGGCC CCGCACCCCC AAGCCGCCGA 2460
CACCACTGCC GATCCAAAGC CAAGCGCTCA CGCCACCACC AGAACCCTCG GGCTGAAGCG 2520
CCCTGCTATG TCTCACACCC CTCACCCGTG CCACCCTCCA CCCCCTGGCC CACCCCACCA 2580
GCCACTACCC CCTTCCCAGC GGTTGTCCAG CCCTACCCTC TCCCAGTGTT CTCTCCTCGA 2640
GGAGGCCCCC AGCCTCTTCC CCCTGCTCCC ACATCTGTGC CCCCAGCTGC TTTCCCCGCC 2700
CCTTTGGTGA CCCCAATGGT GGCCTTGGTG CTCCCTAACT ATCTGTTCCC AACCCCATCC 2760
AGCTATCCTT ATGGGGCACT CCAGACCCCT GCTGAAGGGC CTCCCACTCC TGCCTCGCAC 2820
TCCCCTTCTC CATCCTTGCC CGCCCTCCCC CCCAGTCCTC CTCACCGCCC GGACTCTCCA 2880
CTGTTCAACT CGAGATGCAG CTCTCCACTC CAGCTCAATC TGCTGCAACT GGAGGAGCTC 2940
CCCCGTGCTG AGGGGGCTGC TGTTGCAGGA GGCCCTGGGA GCAGTGCCGG GCCCCCACCT 3000
CCCAGTGCGG AGGCTGCTGA GCCAGAGGCC AGACTGGCGG AGGTCACTGA GTCCTCCAAT 3060
CAGGATGCAC TTTCCGGCTC CAGTGACCTG CTCGAACTTC TGCTGCAAGA GGACTCGCGC 3120
TCCGGCACAG GCTCCGCAGC CTCGGGCTCC TTGGGCTCTG GCTTGGGCTC TGGGTCTGGT 3180
TCAGGCTCCC ATGAGGGGGG CAGCACCTCA GCCAGCATCA CTCGCAGCAG CCAGAGCAGC 3240
CACACAAGCA AATACTTTGG CAGCATCGAC TCTTCCGAGG CTGAGGCTGG GGCTGCTCGG 3300
GGCGGGGCTG AGCCCGGGGA TCAGGTGATT AAGTACGTGC TCCAGGATCC CATTTGGCTG 3360
CTCATGGCCA ATGCTGACCA GCGCGTCATG ATGACCTACC AGGTGCCCTC CAGGGACATG 3420
ACCTCTGTGC TGAAGCAGGA TCGGGAGCGG CTCCGAGCCA TGCAGAAGCA GCAGCCTCGG 3480
TTTTCTGAGG ATCAGCGGCG GGAACTGGGC GCTGTGCACT CCTGGGTCCG GAAGGGCCAA 3540
CTGCCTCGGG CTCTTGATGT GATGGCCTGT GTGGACTGTG GGAGCAGCAC CCAAGATCCT 3600
GGTCACCCTG ATGACCCACT CTTCTCAGAG CTGGATGGAC TGGGGCTGGA GCCCATGGAA 3660
GAGGGTGGAG GCGAGCAGGG CAGCAGCGGT GGCGGCAGTG GTGAGGGAGA GGGCTGCGAG 3720
GAGGCCCAAG GCGGGGCCAA GGCTTCAAGC TCTCAGGACT TGGCCATGGA GGAGGAGGAA 3780
GAAGGCAGGA GCTCATCCAG TCCAGCCTTA CCTACAGCAG GAAACTGCAC CAGCTAG 3837
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus61.46 0.00e+00 1452.6
CGD-GaM-021007Gadus morhua55.6 1.00e-180 630.9
CGD-HoS-021038Homo sapiens (Human)65.81 0.00e+00 1588.5
CGD-OvA-022197Ovis aries63.7 0.00e+00 1439.5
CGD-RaN-021793Rattus norvegicus63.06 0.00e+00 1442.2
Gene Ontology

GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0005515--protein binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation