CGDB Gene Information

Tag Content
CGDB ID CGD-MuP-028062
Ensembl Accession ENSMPUP00000008148.1
Protein Name PER1
Ensembl Information ENSMPUG00000008208; ENSMPUT00000008277
Organism Mustela putorius furo
NCBI Taxa ID 9669
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 19 ZT 7 LD 2 muscle Predicted from orthologs H8ZXB9
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSGPLEGADG GGDPGQGESF CPGGAPSPGP PQHRSCPAPS LADDTDANSN GSSGNESNGP 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCAMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGC IVYISEQAGV 240
LLRCKRDVFR GARFSELLAP QDVGVFYGST APSRLPTWGA GTSAGSGTKD FTQEKSVFCR 300
IRGGPDRDSG PRYQPFRLTP YVTKIRVSEG AAAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAL 480
SLDSDIQELS EQIHRLLLQP VHSPSPTGLC GVGPIASPGP LLSPGSSSDS NGGDAEGPGP 540
PVPVTFQQIC KDVHLVKHQG QQLFIESRAR PPARPRLPAT GTFKAKTLSC QSPDPELEMV 600
PAPLQAPLAL SPEEAERKDA STCSYQQINC LDSILRYLES CNIPSTTKRK CASSSSCTAS 660
SASDDDKQRT GPVPLGAKKD PVPAVLSGEG AGPQKEPVVG GALSPLALAN KAESVVSVTS 720
QCSFSSTIVH VGDKKPPESD IIMMEDLPGL APGPAPSPAP SPTVAPDPTP DAYRPVGLTK 780
AVLSLHTQKE EQAFLSRFRD LSRLRTLDGS SPAPLAPGER GCHHGPAPHG RRHHCRSKAK 840
RSRHHQTPRA DAPCYGSHPP PVSPSAPWPP PAAAAPFPAM VQSYPLPVFS TRGGPQPLPS 900
APTAGPPAAF PAPLVTPMVA LVLPNYLFPT PSSYPYGVAQ TPAEGPPTPA SHSPSPSLPP 960
PPPSPPRRPD SPLFNSRCSS PLQLNLLQLE EPPRVEGGTV AGGPGNSAGP PPSGEEATEP 1020
EARLAEVTES SNQDALSGSS DLLELLLQDS RSGTGSAASG SLGSGLGSGS GSGSHEGGST 1080
SASITRSSQS SHTSKYFGSI DSSEAEAGAA QARAEPGDQV IKYVLQDPIW LLMANADQHV 1140
MMTYQVPSRD VASVLKQDRE RLRAMQKQQP RFSEDQRREL GAVHSWVRKG QLPRALDVMA 1200
CVDCGSSTQD PQHSDDPLFS ELDGLGLEPM EEGGGEGGGG EGEGREETRA GAGARVSSSQ 1260
DLAMEEEEQG GSSSSPALPA TENGTS 1286
Nucleotide Sequence
(Fasta)		 GTCGGACTTC CAGCCCGAGG CGCTGCTTTC GGCCCTGGCG CTCGGACGGC ACACGGTGCT 60
GCCCGTGATC AAACTTCCCA ATCTTCAGAG GCTTGGATCT CCCTCACTCC CGCAGCCAGG 120
CCGGCGGGCC CCCTCGTTTG CTCGTGGTGG CCTCTCCGCC TTCCGTGTTT TCCTCCTGCC 180
CTCCCCATGG CCCAGACATG AGTGGCCCCC TAGAAGGGGC TGATGGGGGT GGGGACCCCG 240
GACAGGGGGA ATCCTTTTGC CCGGGAGGGG CCCCATCCCC TGGGCCTCCG CAGCACCGGT 300
CTTGCCCTGC TCCCAGCCTG GCTGATGACA CAGATGCCAA CAGCAATGGC TCCAGCGGTA 360
ATGAATCCAA TGGGCCTGAG TCCCGGGGGG CATCTCAGCG GAGCTCACAC AGCTCCTCCT 420
CGGGCAACGG CAAGGACTCA GCCCTGTTGG AGACCACTGA GAGCAGCAAG AGCACAAACT 480
CTCAGAGTCC ATCCCCGCCC AGCAGTTCCA TTGCCTACAG TCTCCTGAGT GCCAGCTCCG 540
AGCAGGACAA CCCATCTACC AGTGGCTGCA GCAGTGAACA GTCAGCCCGG GCGAGGACCC 600
AGAAGGAACT CATGACGGCT CTGCGGGAGC TCAAGCTTCG GCTTCCTCCC GAGCGCCGGG 660
GCAAGGGCCG CTCTGGGACG CTGGCCACGC TCCAGTACGC CCTGGCCTGT GTGAAGCAGG 720
TGCAGGCCAA CCAGGAGTAC TACCAGCAGT GGAGCCTGGA AGAGGGCGAG CCCTGCGCCA 780
TGGACATGTC CACCTACACG TTGGAGGAGC TGGAGCACAT CACGTCGGAG TACACACTGC 840
GCAATCAGGA CACCTTCTCC GTGGCGGTCT CCTTCCTGAC AGGCTGCATC GTCTACATTT 900
CGGAGCAGGC GGGGGTCTTG CTGCGCTGTA AACGGGACGT GTTCCGGGGG GCCCGCTTCT 960
CGGAGCTGCT GGCGCCCCAG GATGTGGGCG TCTTCTATGG CTCCACGGCT CCGTCTCGCC 1020
TGCCCACCTG GGGTGCTGGG ACCTCGGCAG GTTCAGGCAC CAAAGATTTC ACCCAAGAGA 1080
AGTCTGTCTT CTGCCGCATC AGAGGAGGTC CTGACCGGGA CTCAGGGCCT CGGTACCAGC 1140
CATTCCGCCT CACGCCCTAT GTGACCAAGA TCCGAGTGTC CGAAGGGGCC GCAGCACAGC 1200
CGTGCTGCCT GCTCATCGCA GAACGCATCC ACTCGGGTTA CGAAGCTCCC CGGATCCCCC 1260
CAGACAAGAG GATCTTCACC ACTCGGCATA CCCCTAGCTG CCTCTTCCAG GACGTGGACG 1320
AAAGGGCCGC CCCGCTGCTG GGCTACCTCC CCCAGGACCT CCTGGGGGCC CCAGTGCTCC 1380
TCTTCTTGCA TCCTGAGGAC CGACCCCTCA TGCTGGCCAT CCACAAGAAG ATCCTGCAGT 1440
TGGCCGGCCA GCCCTTTGAT CACTCCCCGA TCCGCTTCTG TGCCCGGAAT GGAGAGTATG 1500
TCACCATGGA CACCAGCTGG GCCGGCTTCG TGCACCCCTG GAGCCGCAAG GTGGCCTTTG 1560
TCTTGGGCCG CCACAAAGTA CGCACGGCAC CCCTGAACGA GGACGTGTTC ACGCCACCGG 1620
CCCCCAGCCC GGCTCTGTCT CTGGACTCCG ACATCCAGGA GCTCTCAGAG CAGATCCACC 1680
GGCTGTTGTT ACAGCCCGTG CACAGCCCCA GTCCCACCGG GCTCTGTGGA GTGGGCCCCA 1740
TCGCTTCCCC GGGCCCTCTC CTCAGCCCTG GCTCGTCCAG TGACAGCAAC GGGGGTGACG 1800
CTGAGGGACC TGGGCCTCCT GTGCCGGTGA CGTTCCAGCA GATCTGTAAG GACGTGCACC 1860
TGGTGAAGCA TCAGGGACAG CAGCTTTTCA TTGAGTCGCG CGCCCGGCCT CCGGCCCGGC 1920
CCCGCCTCCC TGCTACAGGC ACATTCAAGG CCAAGACCCT TTCCTGCCAG TCACCAGACC 1980
CGGAACTGGA AATGGTCCCT GCTCCCCTCC AGGCCCCACT CGCCTTGAGC CCTGAAGAGG 2040
CTGAGAGGAA AGATGCGTCC ACTTGTTCCT ACCAGCAGAT CAACTGCCTG GACAGCATCC 2100
TCCGGTACCT GGAGAGCTGC AACATCCCCA GCACAACCAA GCGGAAGTGT GCCTCCTCGT 2160
CGTCCTGTAC TGCCTCCTCA GCCTCCGACG ACGACAAGCA GAGGACGGGT CCGGTCCCTT 2220
TGGGGGCCAA GAAAGATCCA GTACCGGCAG TGCTGTCCGG GGAGGGGGCC GGCCCACAGA 2280
AGGAGCCCGT GGTAGGAGGC GCCCTGAGCC CGCTCGCCCT GGCCAATAAG GCGGAGAGCG 2340
TGGTGTCTGT CACCAGCCAG TGTAGCTTCA GCTCCACCAT CGTCCATGTG GGAGACAAGA 2400
AGCCCCCGGA GTCGGACATC ATCATGATGG AGGACCTGCC TGGCCTGGCT CCAGGCCCAG 2460
CCCCCAGCCC AGCCCCCAGC CCCACGGTAG CCCCCGACCC CACCCCAGAC GCCTATCGCC 2520
CGGTGGGCCT AACCAAGGCC GTGCTGTCCC TGCACACGCA GAAGGAGGAA CAGGCCTTCC 2580
TCAGCCGCTT CCGAGACCTC AGCCGACTGC GGACACTTGA TGGCTCCTCC CCGGCCCCCC 2640
TGGCCCCTGG CGAGCGAGGC TGCCACCACG GCCCCGCACC CCACGGTCGC CGACACCACT 2700
GCCGCTCCAA AGCCAAGCGC TCCCGCCACC ACCAGACCCC CCGGGCTGAT GCCCCTTGTT 2760
ATGGCTCCCA CCCGCCGCCT GTGTCACCCT CGGCCCCATG GCCCCCCCCA GCAGCCGCTG 2820
CTCCCTTCCC AGCCATGGTC CAGTCCTACC CTCTCCCAGT ATTCTCCACT CGAGGAGGCC 2880
CCCAGCCTCT CCCCTCTGCC CCCACAGCTG GGCCCCCTGC AGCTTTCCCT GCCCCGCTGG 2940
TGACGCCTAT GGTAGCCTTG GTCCTCCCTA ACTACCTGTT CCCCACCCCA TCTAGCTATC 3000
CCTATGGGGT AGCCCAGACC CCCGCTGAAG GGCCTCCCAC CCCCGCTTCC CACTCCCCTT 3060
CTCCGTCCCT GCCCCCACCG CCCCCCAGCC CTCCTCGCCG GCCAGACTCT CCACTATTCA 3120
ACTCCCGATG CAGCTCCCCA CTCCAGCTGA ATCTGCTACA GCTTGAGGAG CCCCCGCGTG 3180
TTGAAGGGGG CACTGTTGCA GGGGGCCCTG GGAATAGTGC TGGGCCCCCG CCCTCCGGCG 3240
AGGAGGCCAC TGAGCCAGAG GCCAGACTGG CGGAGGTGAC CGAGTCCTCC AACCAGGACG 3300
CGCTGTCGGG CTCCAGTGAC CTGCTGGAGC TGCTGCTGCA GGACTCCCGC TCTGGCACAG 3360
GCTCCGCCGC TTCCGGCTCC CTGGGCTCCG GCCTGGGCTC TGGCTCTGGC TCAGGCTCCC 3420
ACGAGGGAGG CAGCACCTCT GCCAGCATCA CACGCAGTAG TCAGAGCAGC CACACGAGCA 3480
AGTACTTTGG CAGCATCGAC TCTTCTGAGG CCGAAGCGGG GGCTGCCCAG GCCAGGGCTG 3540
AGCCCGGGGA CCAGGTCATT AAATACGTGC TCCAGGATCC CATCTGGCTG CTCATGGCCA 3600
ACGCTGACCA GCATGTCATG ATGACCTACC AGGTGCCGTC CAGGGACGTG GCCTCTGTGC 3660
TGAAGCAGGA CCGGGAGCGG CTCCGGGCCA TGCAGAAGCA GCAGCCTCGG TTCTCAGAGG 3720
ACCAGCGCAG GGAGCTGGGT GCCGTGCACT CCTGGGTCCG GAAGGGTCAG CTGCCTCGGG 3780
CTCTCGATGT GATGGCCTGT GTGGATTGTG GCAGTAGCAC CCAAGACCCT CAACACTCTG 3840
ATGACCCCCT CTTCTCAGAA CTGGATGGAC TGGGACTGGA GCCTATGGAG GAGGGCGGAG 3900
GCGAGGGTGG GGGTGGGGAG GGCGAAGGCA GAGAAGAGAC TCGGGCTGGA GCTGGGGCCA 3960
GAGTCTCCAG CTCTCAGGAC CTGGCCATGG AGGAGGAGGA ACAAGGTGGG AGCTCATCCA 4020
GTCCAGCCTT ACCTGCCACA GAAAATGGCA CCAGCTAGAC CACATTTGAG GGCCCCCTGC 4080
GGCAGTGCAT GAGAAGCTTC CTTCTCCCAC GTTCAACCTC TCAGAACTCC GATGTGGCTG 4140
GACCGACCGA TAGGAAACTA CCCCAGCTTC TCCCTCTTAG GGGGCGGGAC CCCCATTAGC 4200
AGTCCAGGAT CCAGGGGCTG CCTCCGGCTT CTGGGGGTAC AGAGGGTGGG ATTCGTCAGC 4260
CCAGCCCAAA GAAGTCTCAT CTCCCAGCTC TGGTGAGGAG CCCTTCCTTC CCCTGGAGGA 4320
GGATGCTGAC ACGCTGCTCA AGTGGTCTCT GAGTCTGGTC CCTGCGGGTT GGGGCTGCAC 4380
TCACTCACTG GGGGAGACCG CCCTCTCTCC GACCTCCTCC CTAAAGGGGA CAGGGAGGGC 4440
CCAAGCAGGA CCCAGCAGTC CGAACCCCTA GCTGCTCCAG GGTGGGGGAG GTTGGTGGAC 4500
CATGGAGTCC CTGGTGCTGC CCCTCAGGTG GGACCCAGGT GTTCTCAGCT GTACCCTCTA 4560
CCGATGGCAT TTGTGTTTTT GATATTGTGT CTGTTGTTAT TTTTTAATAC AAAGAGGAAA 4620
AAGAAAACAG GACTTTGTGG AATGAAATGT GGGGGTTGGG AGCAGCGAGC TCATTGTGGG 4680
GAGGTGTGGC CCCCCTGCCA GGGAGGCTGT AGTGAGTGTG AGCGACCCCT CCACTTGCGC 4740
CCCTCAGCTC TCTGCTTCGC TCACCCTGTC CAGCGGAGGG GCCTTGCTGA GCCCGGAAGA 4800
TGTCCAGCTA ACTGTGACCC TGCACCCCTC ATCACCTTGC ATCAGCTGGG TGTGTCGAGG 4860
GAAGGGGGTG GCGGCTGGTG CGCCCGCCCA GCCTGTGGGG GCCCTGAAGC AGGTGAGGGT 4920
GCTTAGCTGC TCGGTCATCT GTCACCACGC AAGAGAAGGC CAGTCCGAGG GGGCGGCAGG 4980
ACTTGAGGTC ACGTACCCAT CCACGGTCGA GTCGGGCCCC TGAGATGTGG GAGACGGGAG 5040
GGGCGGAGCG TTAAGTCACC GGCTCGGGAC CTGGAAAAGG AGGGGAAAAC TTTGGAGCCC 5100
ACGTCACAGA GGACCCGCGA CGACCGTCGT TCTGTGTGTG GGTTTCACCT ACCTACTCTC 5160
CGGAGTGGCT GATCTACCTT CAGACTGAAA GCACCTCCCG CCGGCGCCGT GGCTTAGCTG 5220
GTTAAAGCGC CTGTCTAGTA AACAGGAGAT CCTGGGTTCG AATCCCAGCG GTGCCTGGCC 5280
CCATGCGAGG TGGTATATTA TTGCTGCGAG GGCGACGCGC CGCCCGCCCT CCAAAGCCCC 5340
GGCCATGGGG CATCCATCAC AAGATTCTTA TTCCTCCGCG GCCAATTCCA CCTGGAGCTT 5400
TCCCCTCGCG CGCACTTTTA GTGGAAATTC GCAGGCTGAC TCCTGCTTCG CTTTCGGGAA 5460
CCGGAGTAAC GCGGGCATGC TTTGCGTTGG AGGACGTGGG CCCTGGCCTT GGGCTCGGGC 5520
TCATTTTGCT CTCGCGGCGC TGAGCTGGGG GGCGGGGAAG GAGAGCGCGA GCAGGGAGAG 5580
CGCGAGCACC GCGACTTCCG CAGCGCCGCG GCCAGCCGCA GGGGGAGGCG CAGGCTCACA 5640
GACGTCCGGA GGCCGGGGGG TGGGGCCGGC GGGAGGCGGG CCCGTTGATA GGCAGCTATA 5700
GTGG 5704
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus60.14 0.00e+00 1379.4
CGD-GaM-021007Gadus morhua53.12 2.00e-170 596.7
CGD-HoS-021038Homo sapiens (Human)59.83 0.00e+00 1397.5
CGD-OvA-022197Ovis aries59.06 0.00e+00 1355.1
CGD-RaN-021793Rattus norvegicus61.56 0.00e+00 1367.4
Gene Ontology

GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0005515--protein binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation