CGDB Gene Information

Tag Content
CGDB ID CGD-PoA-067892
Ensembl Accession ENSPPYP00000008937.2
Protein Name PER1
Ensembl Information ENSPPYG00000007949; ENSPPYT00000009303
Organism Pongo abelii
NCBI Taxa ID 9601
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MSGPLEGADG GGDPRPGESF CPGGVPSPGP PQHRPCPGPS LADDTDANSN GSSGNESNGH 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PEHRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEES EPCSMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGR IIYISEQAAV 240
LLRCKRDVFR GTRFSELLAP QDVGVFYGST APSRLPTWGT GASAGSGLRD FTQEKSIFCR 300
IRGGPDRDPG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR NVAFVLGYLE SCNLPSTTKR KCASSSSYTT 480
SSASDDDRQR TGPVSVGTKK DPPSAVLSGE GATPRKEPVV GGTLSPLALA NKAESVVSVT 540
SQCSFSSTIV HVGDKKPPES DIIMMEDLPG LAPGPAPSPA PSPTVAPDPA PDAYRPVGLT 600
KAVLSLHTQK EEQAFLSRFR DLGRLRGLDS SSTAPSALGE RGCHHGPAPP SRRHHCRSKA 660
KRSRHHQNPR AEAPCYVSHP SPVPPSTPWP TPPATTPFPA VVQPYPLPVF SPRGGPQPLP 720
PAPTSVPPAA FPAPLVTPMV ALVLPNYLFP TPSSYPYGAL QTPAEGPPTP ASHSPSPSLP 780
ALPPSPPHCP DSPLFNSRCS SPLQLNLLQL EELPRAEGAA VAGGPGSSAG PPPPSEEAAE 840
PEARLVEVTE SSNQDALSGS SDLLELLLQE DSRSGTGSAA SGSLGSGLGS GSGSGSHEGG 900
STSASITRSS QSSHTSKYFG SIDSSEAEAG AARGGAEPGD QVIKYVLQDP IWLLMANADQ 960
RVMMTYQVPS RDMTSVLKQD RERLRAMQKQ QPRFSEDQRR ELGAVHSWVR KGQLPRALDV 1020
MACVDCGSST QEPGHPDDPL FSELDGLGLE PMEEGGGEQG SSGGGSGEGE GCEEAQGGAK 1080
ASSSQDLTME EDEGRSSSSP ALPTAGNCTS
Nucleotide Sequence
(Fasta)		 GTACTGGCTG TGATCGAACT TCTCAACCGT CAGAGACTTA GATCTTCCAC CTCACTCCCT 60
CAGACAGGCC TCCAGGCCCC CCTCGTGCAT CCGTGGTGGC CTCTCCGCCT TTTCTGTTCT 120
GTTCTGCCCA TGGCCCAGAC ATGAGTGGCC CCCTAGAAGG GGCTGATGGG GGAGGGGACC 180
CCAGGCCTGG GGAATCATTT TGTCCTGGGG GCGTCCCATC CCCTGGGCCC CCACAGCACC 240
GGCCTTGCCC AGGCCCCAGC CTGGCCGATG ACACCGATGC CAACAGCAAT GGTTCAAGCG 300
GCAATGAGTC CAATGGGCAT GAGTCTAGAG GTGCATCTCA GCGGAGCTCA CACAGCTCCT 360
CCTCAGGCAA CGGCAAGGAC TCAGCCCTGC TGGAGACCAC TGAGAGCAGC AAGAGCACAA 420
ACTCTCAGAG CCCATCCCCA CCCAGCAGTT CCATTGCCTA CAGCCTTCTG AGTGCCAGCT 480
CAGAGCAGGA CAACCCGTCC ACCAGTGGAT GCAGCAGTGA ACAGTCAGCC CGGGCGAGGA 540
CCCAGAAGGA ACTCATGACA GCACTTCGAG AGCTCAAGCT TCGACTGCCG CCAGAGCACC 600
GGGGCAAGGG CCGCTCTGGG ACCCTGGCCA CGCTGCAGTA CGCACTGGCC TGTGTCAAGC 660
AGGTGCAGGC CAACCAGGAA TACTACCAGC AGTGGAGCCT GGAGGAGAGC GAGCCTTGCT 720
CCATGGACAT GTCCACCTAT ACCCTGGAGG AGCTGGAGCA CATCACGTCT GAGTACACGC 780
TTCGGAACCA GGATACCTTC TCAGTGGCTG TCTCCTTCCT GACGGGCCGA ATCATCTACA 840
TTTCGGAGCA GGCAGCTGTC CTGCTGCGTT GCAAGCGGGA CGTGTTCCGG GGTACCCGCT 900
TCTCTGAGCT CCTGGCTCCC CAGGATGTGG GAGTCTTCTA TGGTTCCACT GCTCCATCTC 960
GCTTGCCCAC CTGGGGCACA GGGGCCTCAG CAGGTTCAGG CCTCAGGGAC TTTACCCAAG 1020
AGAAGTCCAT CTTCTGCCGT ATCAGAGGAG GTCCTGACCG GGATCCAGGG CCTCGGTACC 1080
AGCCATTCCG CCTAACCCCG TATGTGACCA AGATCCGGGT CTCAGATGGG GCCCCTGCAC 1140
AGCCGTGCTG CCTGCTGATT GCAGAGCGCA TCCATTCGGG TTATGAAGCT CCCCGGATAC 1200
CCCCTGACAA GAGGATTTTC ACTACGCGGC ACACACCTAG CTGCCTCTTC CAGGATGTGG 1260
ATGAAAGGGC TGCCCCCCTG CTGGGCTACC TGCCCCAGGA CCTCCTGGGG GCCCCAGTGC 1320
TCCTGTTCCT GCATCCTGAG GACCGACCCC TCATGCTGGC TATCCACAAG AAGATCCTGC 1380
AGTTGGCGGG CCAGCCCTTT GACCACTCCC CTATCCGCTT CTGTGCCCGC AACGGGGAGT 1440
ATGTCACCAT GGACACCAGC TGGGCTGGCT TTGTGCACCC CTGGAGCCGC AATGTAGCCT 1500
TCGTGTTGGG GTACCTGGAG AGCTGCAACC TCCCCAGCAC CACTAAGCGT AAATGTGCCT 1560
CCTCATCCTC CTATACCACC TCCTCAGCCT CTGACGACGA CAGGCAGAGG ACAGGTCCAG 1620
TCTCTGTGGG GACCAAGAAA GATCCGCCGT CAGCAGTGCT GTCTGGGGAG GGGGCCACCC 1680
CACGGAAGGA GCCAGTGGTG GGAGGCACCC TGAGCCCGCT CGCCCTGGCC AATAAGGCGG 1740
AGAGCGTGGT GTCCGTCACC AGTCAGTGTA GCTTCAGCTC CACCATCGTC CATGTGGGAG 1800
ACAAGAAGCC CCCGGAGTCG GACATCATCA TGATGGAGGA CCTGCCTGGC CTAGCCCCAG 1860
GCCCAGCCCC CAGCCCAGCC CCCAGCCCCA CAGTAGCCCC TGACCCAGCC CCAGATGCCT 1920
ACCGTCCAGT GGGGCTGACC AAGGCCGTGC TGTCCCTGCA CACACAGAAG GAGGAGCAAG 1980
CCTTCCTCAG CCGCTTCCGA GACCTGGGCA GGCTGCGTGG ACTCGACAGC TCTTCCACAG 2040
CTCCCTCAGC CCTTGGCGAG CGAGGCTGCC ACCACGGCCC CGCACCCCCA AGCCGCCGAC 2100
ACCACTGCCG ATCCAAAGCC AAGCGCTCAC GCCACCACCA GAACCCTCGG GCTGAAGCGC 2160
CCTGCTATGT CTCACACCCC TCACCCGTGC CACCCTCCAC CCCCTGGCCC ACCCCACCAG 2220
CCACTACCCC CTTCCCAGCG GTTGTCCAGC CCTACCCTCT GCCAGTGTTC TCTCCTCGAG 2280
GAGGCCCCCA GCCTCTTCCC CCTGCTCCCA CATCTGTGCC CCCGGCTGCT TTCCCCGCCC 2340
CTTTGGTGAC CCCAATGGTG GCCTTGGTGC TCCCTAACTA TCTGTTCCCA ACCCCATCCA 2400
GCTATCCTTA TGGGGCACTC CAGACCCCTG CTGAAGGGCC TCCCACTCCT GCCTCGCACT 2460
CCCCTTCTCC ATCCTTGCCC GCCCTCCCCC CCAGCCCTCC TCACTGCCCG GACTCTCCGC 2520
TGTTCAACTC GAGATGCAGC TCTCCACTCC AGCTCAATCT GCTGCAGCTC GAGGAGCTCC 2580
CCCGTGCTGA GGGGGCTGCT GTCGCAGGGG GCCCTGGGAG CAGTGCTGGG CCCCCACCTC 2640
CCAGTGAGGA GGCTGCTGAG CCAGAGGCCA GACTGGTGGA GGTCACTGAG TCCTCCAATC 2700
AGGACGCACT TTCCGGCTCC AGTGACCTGC TGGAACTTCT GCTGCAAGAG GACTCACGCT 2760
CCGGCACAGG CTCCGCAGCC TCGGGCTCCT TGGGCTCTGG CTTGGGCTCT GGGTCTGGTT 2820
CAGGCTCCCA TGAGGGGGGC AGCACCTCAG CCAGCATCAC TCGCAGCAGC CAGAGCAGCC 2880
ACACAAGCAA ATACTTTGGC AGCATCGACT CTTCTGAGGC TGAGGCTGGG GCTGCTCGGG 2940
GCGGGGCTGA GCCCGGGGAC CAGGTGATTA AGTACGTGCT CCAGGATCCC ATTTGGCTGC 3000
TCATGGCTAA TGCTGACCAG CGCGTCATGA TGACCTACCA GGTGCCCTCC AGGGACATGA 3060
CCTCTGTGCT GAAGCAGGAT CGGGAGCGGC TCCGAGCCAT GCAGAAGCAG CAGCCTCGGT 3120
TTTCTGAGGA CCAGCGGCGG GAACTGGGCG CTGTGCACTC CTGGGTCCGG AAGGGCCAAC 3180
TGCCTCGGGC TCTTGATGTG ATGGCCTGTG TGGACTGTGG GAGCAGCACC CAAGAGCCTG 3240
GTCACCCCGA TGACCCACTC TTCTCAGAGC TGGATGGACT GGGGCTGGAG CCCATGGAAG 3300
AGGGTGGAGG CGAGCAGGGC AGCAGCGGTG GCGGCAGTGG TGAGGGTGAG GGCTGCGAGG 3360
AGGCCCAAGG CGGGGCCAAG GCTTCAAGCT CTCAGGACTT GACCATGGAG GAGGACGAAG 3420
GCAGGAGCTC ATCCAGTCCG GCCTTACCTA CAGCAGGAAA CTGCACCAGC TAGACTCCAT 3480
TCTGGGACCA TCTCCAGGGG TCCACGAGAG GCTTTCTTCT CCTATGTCCC AATTCTCAGA 3540
ACTCAGATGT GGCTAGACCA ACCAGTGGGA AACTGCCCCA GCCTCTCCCA CCATAGGGGG 3600
CCGGACCCCC ATCACCAGCC TAGGATCCAG GGGCTGCCTC TGGCCTCTTA GGGAGCAGAG 3660
AGCAGAACTC CGCAGCCCAG CCCAGAGGAG TGTCACCTCC CACCTTTGAA GAGGAATCCT 3720
TCCCTCCCCT GGACAGAGTT GCTGACAAGC TGCTGAAGTG GCCTCTCCAT ATTCCAGCTG 3780
AGCCTGAATC CGACTCCTGA GGGTTGGGGC TGCACTTATT TATTGGGGGA GACAGTTCTG 3840
TCTCCCACCT CCTCCCCAGA TGGGAGGAGA GCCTGAGGCC CAAGCAGGAC CCGGGGGTTC 3900
CAGCCCCTAG CTGCTCTGGG GTGGGGGAGG TTGGTGGACC ATGGAGTCCC TGGTGCTGCC 3960
CCTCAGGTGG GACCCAGGCG TTCTCAGCTG TACCCTCTGC CGATGGCATT TGTGTTTTTG 4020
ATATTTGTGT CTGTTACTAC TTTTTTAATA CAAAAAGATA AAAACGCACA GGACTTTGTG 4080
GAA 4083
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus77.02 0.00e+00 705.3
CGD-HoS-021038Homo sapiens (Human)80.53 0.00e+00 738.8
CGD-OvA-022197Ovis aries78.07 0.00e+00 716.8
CGD-RaN-021793Rattus norvegicus79.21 0.00e+00 730.3
Gene Ontology

GO:0005515--protein binding
GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0051591--response to cAMP
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus