CGDB Gene Information

Tag Content
CGDB ID CGD-OtG-066239
Ensembl Accession ENSOGAP00000021991.1
Protein Name PER1
Ensembl Information ENSOGAG00000026695; ENSOGAT00000028495
Organism Otolemur garnettii
NCBI Taxa ID 30611
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 ASVVSSSPSL FSCPSHGPDM SGPLEGADGG GDPRPGESFC PGGVPSPGPP QHWPCPGPSP 60
ADDTDANSNG SSGNESNGHE SRGASQRSSH SSSSGNGKDS ALLETTESSK STNSQSPSPP 120
SSSIAYSLLS ASSEQDNPST SGCSSEQSAR ARTQKELMTA LRELKLRLPP ERRGKGRSGT 180
LATLQYALAC VKQVQANQEY YQQWSLEEGE PCDMDMSTYT LEELEHITSE YTLRNQDTFS 240
VAVSFLTGRI VYISEQAGIL LRCKRDVFRG ARFSELLAPQ DVGVFYGSTA PSRLPTWGTG 300
ASAGSGLKDF TQEKSVFCRI RGGPDRDPGP RYQPFRLTPY VTKIRVSDGA PAQPCCLLIA 360
ERIHSGYEAP RIPPDKRIFT TRHTPSCLFQ DVDERAAPLL GYLPQDLLGA PVLLFLHPED 420
RPLMLAIHKK ILQLAGQPFD HSPIRFCARN GEYVTMDTSW AGFVHPWSRK VAFVLGRHKV 480
RTAPLNEDVF TPLAPIPAPS LDTDIQELSE QIHRLLLQPV HSSSPSGLCG VGPVTSPGPL 540
HSPGSSSDSN GGDAEGPGPP APVTFQQICK DVHLVKHQGQ QLFIESRAQP PSRPHLPATS 600
IFKAKALPFQ SSDPEPEMAP ALIQAPLALA PEEAERKEAS NCSYQQINCL DSILRYLESC 660
NIPSTTKRKC ASSSSYTASS ASDDDKQRTG PVPVGTKKDP SSTMLSGEGA SPQKEPVVGG 720
TLSPLTLANK AESVVSVTSQ CSFSSTIVHV GDKKPPESDI IMMEDLPGLA PGPAPSPAPS 780
PTVAPDPAPD AYRPVGLTKA VLSLHTQKEE QAFLSRFRDL GRLRGLDSSS TAPSAPGCHH 840
GPAPPGRRHH CRSKAKRSRH HQTPRAEAPC YVSHPSPVPP SAAWPPPPAT TPFPAVVQPY 900
PFPVFSPRGG PQPLPPAPTS VPPATFPTPL VTPMVALVLP NYLFPAPSSY PYGAPQTSAE 960
GPLTPASQSP SPSLPPLPPS PPHCPDSPLF NSRCSSPLQL NLLQLEEPPR AEGGTVAGGP 1020
GSNAGPPPPS EEAAEPEARL VEVTESSNQD ALSGSSDLLE LLLQEDSRSG TGSAASGSLG 1080
SGLGSGSGSG SHEGGSTSAS ITRSSQSSHT SKYFGSVDSS EAEAGAAQAR AEPGDQVIKY 1140
VLQDPIWLLM ANADQKVMMT YQVPSRDMTS VLKQDRERLR AMQKQQPRFS EDQRRELGAV 1200
HSWVRKGQLP RALDVMACVD CSSSAQDPGH PDDPLFSELD GLGLEPMEEG GGEGVSGGGS 1260
GEGEGLEEAQ AQVEAKVSSS QDLAMEEEEQ GGNLPSPALP TIENGTT 1307
Nucleotide Sequence
(Fasta)		 CCAGGTAGTG GCTGTGATCA AACATCTCAA ACCTCAGAGA CTTAGATCTC CCGCCTCACA 60
GTCTCACCCA GGCCTCTAGG CCCCTCGTGC ATCTGTGGTG TCCTCTTCAC CTTCTCTGTT 120
TTCCTGTCCT TCCCATGGCC CAGACATGAG CGGCCCCCTA GAAGGGGCCG ATGGGGGAGG 180
GGACCCCAGG CCCGGGGAAT CTTTCTGTCC TGGAGGGGTC CCATCCCCAG GGCCCCCCCA 240
GCACTGGCCT TGCCCGGGCC CCAGCCCCGC AGATGACACT GATGCCAACA GCAATGGCTC 300
AAGTGGCAAT GAATCCAACG GGCATGAGTC CAGGGGTGCA TCTCAGCGGA GCTCGCACAG 360
TTCCTCCTCT GGCAATGGCA AGGACTCAGC CCTGCTGGAG ACCACGGAGA GCAGCAAGAG 420
CACAAACTCT CAGAGCCCAT CCCCACCTAG CAGTTCCATT GCCTACAGCC TCCTGAGTGC 480
CAGCTCGGAG CAGGACAACC CATCTACCAG TGGCTGCAGC AGTGAGCAGT CAGCTCGAGC 540
AAGGACCCAG AAGGAACTCA TGACTGCACT TCGGGAGCTC AAGCTTCGAT TGCCGCCAGA 600
GCGCCGGGGA AAGGGCCGCT CTGGAACCCT GGCCACGCTA CAGTATGCAC TGGCCTGTGT 660
CAAACAGGTG CAGGCCAACC AGGAATACTA CCAGCAGTGG AGCCTGGAGG AGGGTGAACC 720
TTGTGACATG GACATGTCCA CCTACACGCT GGAGGAGCTG GAGCACATAA CATCTGAGTA 780
CACACTTCGC AACCAGGATA CTTTCTCGGT GGCTGTCTCC TTCCTGACAG GCCGAATTGT 840
CTACATTTCG GAGCAAGCAG GTATCCTGCT GCGTTGCAAG CGGGATGTGT TCCGGGGTGC 900
CCGTTTCTCA GAGCTCCTGG CTCCCCAGGA TGTGGGTGTC TTCTATGGTT CCACTGCCCC 960
ATCTCGCCTG CCCACCTGGG GCACCGGGGC CTCAGCAGGT TCAGGCCTCA AGGACTTCAC 1020
CCAGGAGAAG TCAGTCTTCT GCCGTATCAG AGGAGGTCCT GACCGGGATC CAGGGCCTCG 1080
GTACCAGCCA TTCCGCCTTA CCCCATATGT GACCAAGATC CGGGTCTCAG ATGGGGCACC 1140
TGCACAGCCA TGCTGCCTGC TAATTGCAGA GCGAATCCAC TCGGGTTATG AAGCTCCCCG 1200
GATACCCCCC GACAAGAGGA TCTTCACCAC ACGGCACACA CCTAGCTGCC TCTTCCAAGA 1260
TGTGGATGAA AGGGCTGCCC CATTGTTGGG CTATCTGCCC CAGGACCTTC TGGGAGCCCC 1320
AGTGCTCCTC TTCCTGCATC CGGAAGACCG ACCCCTCATG TTGGCTATCC ACAAGAAGAT 1380
CCTGCAGCTG GCAGGCCAGC CCTTTGATCA CTCTCCTATC CGCTTCTGTG CCCGTAATGG 1440
GGAGTATGTG ACCATGGACA CCAGCTGGGC TGGATTTGTA CACCCCTGGA GCCGCAAGGT 1500
GGCCTTTGTG TTGGGTCGCC ACAAAGTACG CACGGCACCC CTGAATGAGG ATGTGTTCAC 1560
TCCACTGGCT CCCATCCCAG CTCCATCCCT GGACACTGAT ATACAGGAGC TGTCAGAGCA 1620
AATCCACCGG CTGCTGTTGC AGCCTGTGCA CAGCTCCAGC CCCTCAGGGC TCTGTGGAGT 1680
TGGCCCTGTG ACATCCCCAG GTCCTCTGCA CAGCCCTGGC TCCTCCAGCG ATAGCAATGG 1740
GGGTGATGCT GAGGGACCTG GGCCTCCTGC CCCGGTGACT TTCCAGCAGA TCTGCAAGGA 1800
TGTGCATCTG GTGAAGCACC AGGGGCAACA ACTCTTTATT GAGTCTCGGG CCCAGCCCCC 1860
ATCCCGGCCC CACCTCCCTG CAACAAGCAT ATTCAAGGCC AAGGCCCTTC CCTTCCAGTC 1920
CTCAGACCCA GAGCCGGAGA TGGCTCCTGC TCTAATCCAG GCCCCATTAG CCTTGGCCCC 1980
TGAGGAGGCT GAGCGGAAAG AAGCCTCCAA CTGCTCTTAC CAGCAAATCA ACTGCCTGGA 2040
CAGCATCCTC AGGTACCTGG AGAGCTGCAA CATCCCCAGC ACAACCAAAC GTAAATGTGC 2100
CTCCTCCTCC TCCTACACGG CCTCTTCGGC CTCTGACGAT GACAAGCAGA GGACAGGTCC 2160
AGTCCCTGTG GGGACCAAGA AAGATCCTTC GTCGACAATG CTGTCTGGGG AGGGGGCCAG 2220
TCCTCAGAAG GAGCCAGTGG TGGGAGGCAC CCTGAGCCCG CTCACCCTGG CCAATAAGGC 2280
GGAGAGCGTG GTGTCCGTCA CCAGTCAGTG TAGCTTCAGC TCCACCATCG TCCATGTGGG 2340
AGACAAGAAG CCCCCGGAGT CGGACATCAT CATGATGGAG GACCTGCCTG GCCTAGCCCC 2400
AGGCCCGGCC CCCAGCCCGG CCCCCAGCCC CACAGTAGCC CCTGACCCAG CCCCAGATGC 2460
ATACCGTCCA GTGGGCCTGA CCAAGGCCGT GCTGTCCCTG CACACACAGA AGGAAGAACA 2520
AGCCTTCCTC AGCCGCTTCC GAGACCTTGG GAGGCTACGT GGACTCGACA GTTCTTCCAC 2580
AGCCCCCTCA GCCCCTGGCT GCCATCATGG CCCCGCACCC CCTGGCCGCC GACACCACTG 2640
CCGATCCAAA GCCAAGCGCT CACGCCACCA CCAGACCCCC CGCGCCGAAG CTCCCTGCTA 2700
TGTCTCCCAC CCATCACCTG TGCCACCCTC TGCCGCCTGG CCCCCCCCAC CAGCCACTAC 2760
CCCCTTCCCA GCAGTGGTCC AACCATACCC CTTCCCAGTA TTCTCCCCTC GAGGAGGCCC 2820
CCAGCCTCTT CCCCCTGCTC CCACTTCTGT GCCCCCTGCC ACTTTCCCCA CCCCACTGGT 2880
GACACCAATG GTGGCCTTGG TGCTCCCTAA CTACCTGTTC CCTGCCCCAT CCAGCTATCC 2940
CTATGGGGCA CCCCAGACCT CCGCTGAGGG GCCTCTCACC CCTGCTTCCC AGTCCCCTTC 3000
CCCATCCCTG CCCCCTCTGC CCCCAAGCCC TCCCCACTGC CCAGACTCTC CACTGTTCAA 3060
CTCAAGATGC AGCTCTCCGC TCCAGCTCAA TCTGCTGCAG CTTGAGGAGC CCCCCCGTGC 3120
TGAGGGGGGC ACTGTTGCAG GGGGCCCTGG GAGTAATGCT GGGCCCCCAC CTCCCAGTGA 3180
GGAGGCTGCT GAGCCAGAGG CCAGACTGGT GGAGGTAACT GAATCCTCCA ATCAGGACGC 3240
ACTTTCTGGC TCCAGTGATC TGCTGGAACT GCTGCTGCAA GAGGACTCTC GCTCTGGCAC 3300
AGGCTCTGCA GCATCAGGTT CCCTAGGCTC TGGCTTGGGC TCTGGGTCTG GTTCAGGCTC 3360
CCATGAGGGG GGCAGTACTT CAGCCAGCAT CACTCGTAGC AGTCAGAGTA GCCACACAAG 3420
CAAGTACTTT GGCAGCGTTG ACTCTTCTGA GGCTGAAGCT GGGGCTGCTC AGGCTAGGGC 3480
TGAGCCTGGG GACCAGGTCA TTAAGTATGT GCTCCAGGAT CCTATCTGGC TGCTCATGGC 3540
CAATGCTGAC CAGAAAGTCA TGATGACTTA CCAGGTGCCC TCCAGAGACA TGACCTCTGT 3600
GCTGAAGCAG GACCGAGAGC GGCTCCGGGC CATGCAGAAG CAGCAGCCTC GGTTCTCAGA 3660
GGACCAGCGG CGGGAACTGG GTGCTGTGCA CTCCTGGGTC CGGAAAGGCC AGCTGCCTCG 3720
GGCCCTTGAT GTTATGGCCT GTGTGGATTG CAGTAGCAGT GCCCAAGACC CTGGCCACCC 3780
TGATGACCCA CTCTTTTCAG AGCTGGATGG ACTGGGGCTG GAGCCTATGG AAGAGGGTGG 3840
AGGCGAGGGG GTCAGTGGTG GTGGCAGTGG TGAGGGTGAG GGCCTGGAGG AGGCCCAAGC 3900
CCAAGTTGAG GCCAAGGTCT CAAGCTCTCA GGACTTGGCT ATGGAGGAGG AGGAACAAGG 3960
TGGGAATTTG CCTAGTCCAG CCTTACCTAC CATAGAAAAT GGCACCACCT AAACTCCATT 4020
TTGGGACCAC CTTTAGGAAT CCATGAGAGG CTTTCTTCCT CCTAAGTTCC AGTTCTTAGA 4080
ACTCAGATGT GGCTAGACCA ATCAATAGGA TATTGTCTAG CTTCTCCCAC TGAAGGGGGC 4140
TGGACCCCCA TCACCAGCCC AGGATCCAGG GACTGCCTCT GGCCTCTTAG GGAACAGAGG 4200
GTGGAACTCC TCAGCCTCGC CCAGTTCAAC CCTTGGTGAG GAGTCCTTCT CTCCTGTGGA 4260
CAAATTTGCT GACAAGCTGC TGAAGTGGTC TTTCCAAATC CCAGCTGAGC CTGAGTCTGG 4320
CTCTGGAGGT TGGGGCTGCA CTTATTTATT GGAGGAGCCA GCTCTCTCTC CCACCTCCTT 4380
CCCATATGGG AGGAGAGCCC AAGGCTCAAG CGCAACCCAG GGGTATGAAC CCCTAGCTGC 4440
TCTAGGGTGG GGGAGGTTGG TGGACCATGG AGTCCCTGGT GCTGCCCCTC AGGTGGGACC 4500
CAGGCGTTCT CAGCTGTACC CTCTACCAAT GGCGTTTGTG TTTTTGATAT TGTGTCTGTT 4560
ATTACTTTTT TTAAT 4575
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus61.11 0.00e+00 1436.4
CGD-HoS-021038Homo sapiens (Human)61.74 0.00e+00 1465.7
CGD-OvA-022197Ovis aries59.16 0.00e+00 1384.4
CGD-RaN-021793Rattus norvegicus61.99 0.00e+00 1406.3
Gene Ontology

GO:0005515--protein binding
GO:0004871--signal transducer activity
GO:0007165--signal transduction
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0032922--circadian regulation of gene expression
GO:0051591--response to cAMP
GO:0007623--circadian rhythm
GO:0019900--kinase binding
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0043966--histone H3 acetylation
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0043967--histone H4 acetylation
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm