CGDB Gene Information

Tag Content
CGDB ID CGD-MoD-062809
Ensembl Accession ENSMODP00000009651.3
Protein Name PER1
Ensembl Information ENSMODG00000007769; ENSMODT00000009842
Organism Monodelphis domestica
NCBI Taxa ID 13616
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 21 ZT 9 LD 6 duodenum Predicted from orthologs Q8QGQ8
ZT 2 ZT 18 LD 3.17 embryos Predicted from orthologs Q8QGQ8
ZT 6 ZT 18 LD 8 embryos Predicted from orthologs Q8QGQ8
CT 12 CT 0 DD1 3 granulosa cells Predicted from orthologs Q8QGQ8
ZT 3 ZT 18 LD 84.29 pineal glands Predicted from orthologs Q8QGQ8
ZT 23 ZT 11 LD 2.25 spleen Predicted from orthologs Q8QGQ8
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 MNGTIEGGNG AGGPGSGPGE QFDSGGSQSP GPPEHRPCPG PGLADDTDAN SNGSSGNESN 60
GPESQGTSQH SSHSSSSGHG KDSALLETTE SSKSTNSQSP SPPSSSIAYS LLSASSEQDN 120
PSTSGCSSEQ SARARTQKEL MTALRELKRR LPPERRGKGR SGTLATLQYA LACVKQVQAN 180
QDYYQQWNLE EGQPCSMDMS SYTLEELEHI TSEYTLRNQD TFSVAVSFLT GQIVYISDQA 240
AVLLRCKREV FRGARFSELL APQDVGVFYG STVPSRLPTW GSRASAGSGP MDFTQEKSVF 300
CRIRGGPDRE SSPRYRPFRL TPYVTKIQLS DGAPAQPCCL LIAERIHSGY EAPRIPPDKR 360
IFTTRHTPSC LFQDVDERAA PLLGYLPQDL LGAPVLLFLH PEDRPLMLAI HKKILQLSGQ 420
PFDHSPIRFC ARNGEYVTMD TSWAGFVHPW SRKVAFVLGR HKVRTAPLNE DVFTPPAPVP 480
IPARGMDPDI QELSEQIHRL LLQPVHSVSP TGLCGLGPPT SPGPFLNPGS SSDSNGGDAD 540
HPGPPVPVTF QQICKDVHLV KHQGQQLFID SRSQSTWPPS SVPDTLKTTS TLPGRPLEPA 600
PGLNPVQPLV VSTAPDDSER KEASNCSYQQ INCLDSIIRY LESCNVPNTV KRKCASSSHT 660
ASSTSDDDRQ KAGQGSGVAK KDPAEELSQE GSPLQKEPVV GGPLTPLTLA NKAESVVSIT 720
SQCSFSSTIV HVGDKKPPES DIVMMEELPG LTSGPAPSPT MATPDPTPDA YRPVGLTKAV 780
LSLHTQKEEQ AFLTRFRDLS KLRVFDTPSV GPSPPNDRGC CHGPIPPGRR HHGKSKAKRS 840
RHHQLSLIET PGYTSHPSPV PPTTPWPPQP NPPASATFPT VVQTYPLPIF STRGCPQPSA 900
PTPSPSPFSS PLVTPMVALV LPNYLFPSPT TSYPCGVPQS LSDRPLTPAP CSPSLTLPPV 960
PPSPTQCPDS PLFNSRCSSP LQLNLLQLEE TTRGEGGATV GEPGSNPRPP PLGEEATQPE 1020
TGLVEMNESS NQDALSGSSD LLELLLQEDS RSGTGSAASG SLASGSGSHG GSTSASITRS 1080
SQSSHTSKYF GSIDSSEAEP TGAQVGVDPG TGPGEQVIKY VLQDPIWLLM ANADHRVMMT 1140
YQVPSRDMAS VLQQDRERLR AMQKQQPRFS EEQRRELGAV HAWVRKGQLP RALDVMACVD 1200
CGSSIPDPQY PDDSLFPELD GLGLEPMEED GGGASPDTAM DEEEQGGELS TSELPALKTN 1260
S 1261
Nucleotide Sequence
(Fasta)		 GTTCCAGCAG TGATCCCTCC CCACAGTCCT CATTGACTTC ACCTTTTGCC GCTTCTTCCC 60
TTCCCTCTCC CCAGCCAAGA AAACTCCTGT CCCAGGGGCC TTGTTGTATT CCCTTGTGGT 120
GGCCTCTCTC CCTTCACTGA TTTTGTCCCT CTGTCCTCCC CATGGTACCA CCATGAATGG 180
CACCATTGAG GGAGGCAATG GGGCAGGGGG CCCAGGCTCT GGGCCTGGTG AACAGTTTGA 240
TTCAGGGGGA TCCCAATCCC CTGGACCCCC CGAACACAGA CCCTGCCCTG GTCCTGGCCT 300
AGCGGATGAT ACAGATGCAA ACAGCAATGG TTCAAGTGGC AATGAGTCCA ATGGACCGGA 360
GTCCCAGGGT ACTTCTCAGC ATAGTTCTCA CAGCTCTTCT TCTGGCCATG GGAAAGACTC 420
TGCCCTTCTG GAAACCACAG AGAGCAGCAA GAGCACCAAC TCTCAGAGTC CATCCCCTCC 480
AAGCAGCTCC ATTGCCTATA GCCTCTTGAG TGCCAGTTCA GAGCAGGACA ATCCATCCAC 540
CAGTGGCTGC AGCAGTGAGC AGTCAGCCCG GGCACGAACA CAGAAGGAGC TAATGACTGC 600
CCTTCGAGAG CTGAAACGTA GACTTCCACC AGAACGAAGA GGGAAAGGCC GATCAGGAAC 660
TTTGGCTACC CTGCAATATG CACTTGCCTG TGTTAAACAA GTCCAGGCCA ATCAAGATTA 720
CTATCAGCAA TGGAACTTAG AGGAAGGGCA GCCTTGTTCC ATGGACATGT CCAGCTATAC 780
CCTGGAGGAG TTAGAGCACA TCACATCTGA GTATACCCTC CGAAATCAGG ATACTTTCTC 840
TGTGGCTGTC TCTTTTCTCA CTGGCCAGAT TGTCTACATT TCGGATCAGG CAGCTGTTCT 900
TCTTCGCTGT AAGAGAGAAG TCTTCCGGGG TGCTCGGTTC TCAGAACTCT TGGCCCCCCA 960
GGATGTGGGT GTTTTCTATG GCTCCACTGT CCCCTCTCGC CTGCCCACGT GGGGCTCTCG 1020
GGCCTCTGCT GGTTCAGGCC CTATGGATTT CACACAAGAG AAATCAGTCT TCTGCAGGAT 1080
CCGAGGTGGC CCAGATCGGG AATCAAGTCC TAGATACCGG CCATTTCGAC TAACCCCCTA 1140
TGTGACCAAG ATCCAGCTCT CAGATGGAGC CCCAGCACAG CCGTGTTGTC TGCTTATTGC 1200
TGAAAGAATT CACTCTGGCT ATGAGGCTCC CAGGATTCCT CCAGACAAGA GGATCTTCAC 1260
AACAAGGCAC ACACCCAGCT GTCTGTTCCA AGATGTAGAT GAGAGGGCTG CCCCACTGTT 1320
GGGATACTTA CCCCAGGACC TGCTAGGTGC ACCAGTGCTC CTTTTCTTGC ACCCTGAAGA 1380
TCGACCTCTT ATGTTGGCAA TCCACAAGAA GATCTTGCAG CTATCAGGTC AACCTTTTGA 1440
CCACTCCCCC ATCCGATTCT GTGCCAGAAA TGGGGAATAT GTCACCATGG ACACCAGTTG 1500
GGCTGGATTT GTCCATCCCT GGAGCCGAAA AGTGGCATTT GTTTTGGGCA GACACAAAGT 1560
TCGAACGGCT CCCCTAAATG AGGATGTATT CACTCCCCCA GCCCCTGTCC CAATCCCCGC 1620
AAGAGGTATG GACCCAGACA TCCAGGAGCT ATCAGAGCAG ATCCACCGGC TACTGCTACA 1680
GCCAGTTCAT AGTGTGAGTC CCACAGGACT GTGTGGATTA GGCCCTCCAA CCTCTCCAGG 1740
TCCCTTCTTA AATCCTGGCT CATCCAGTGA CAGTAATGGT GGAGATGCTG ATCATCCTGG 1800
GCCCCCTGTT CCTGTGACAT TCCAGCAGAT CTGTAAAGAT GTGCATCTTG TGAAGCACCA 1860
GGGTCAGCAG CTTTTCATTG ACTCTCGCTC CCAATCCACC TGGCCCCCAT CCTCAGTCCC 1920
AGATACTCTT AAGACCACCA GTACCCTCCC AGGAAGACCC TTGGAACCAG CCCCTGGACT 1980
GAATCCAGTT CAGCCTCTTG TGGTCAGTAC CGCCCCTGAT GATTCAGAGA GAAAAGAAGC 2040
ATCCAATTGT TCCTACCAGC AGATCAATTG CCTGGACAGC ATTATCCGGT ACCTGGAGAG 2100
TTGCAATGTC CCCAACACAG TGAAGAGAAA ATGTGCTTCC TCCTCTCACA CAGCATCTTC 2160
CACCTCTGAT GATGACAGAC AGAAGGCAGG CCAGGGTTCT GGAGTGGCCA AGAAAGATCC 2220
AGCAGAAGAG CTGTCTCAGG AGGGGTCCCC CCTCCAGAAG GAGCCAGTGG TGGGAGGTCC 2280
ACTGACCCCG CTCACCCTTG CCAATAAGGC GGAGAGTGTG GTATCCATCA CAAGTCAGTG 2340
TAGCTTCAGC TCTACTATCG TCCATGTAGG AGACAAGAAG CCCCCGGAGT CGGATATTGT 2400
CATGATGGAA GAGTTGCCTG GCCTGACCTC TGGTCCAGCT CCCAGTCCAA CGATGGCCAC 2460
TCCTGACCCC ACCCCTGATG CCTACCGCCC TGTGGGATTG ACCAAAGCTG TACTGTCACT 2520
TCATACACAG AAAGAGGAGC AGGCCTTCCT CACCCGATTT CGGGATCTCA GCAAACTCCG 2580
GGTCTTTGAT ACCCCTTCCG TTGGACCTTC ACCTCCTAAT GATCGAGGCT GTTGCCATGG 2640
TCCCATTCCT CCTGGCCGCC GACACCATGG CAAATCAAAA GCCAAACGTT CAAGGCACCA 2700
TCAGCTCTCT CTGATTGAGA CCCCTGGCTA TACCTCTCAT CCTTCCCCAG TACCTCCTAC 2760
CACTCCATGG CCTCCTCAAC CTAACCCACC GGCCTCTGCT ACTTTCCCAA CAGTGGTGCA 2820
AACCTACCCA TTACCCATTT TTTCAACCAG AGGTTGTCCC CAACCTTCAG CACCTACCCC 2880
ATCTCCTTCA CCCTTTTCCT CCCCCTTAGT AACTCCTATG GTGGCTTTGG TCCTACCCAA 2940
CTATTTGTTT CCTTCTCCTA CTACCAGTTA CCCCTGTGGG GTACCTCAGT CTCTATCAGA 3000
CAGGCCTCTT ACCCCTGCAC CATGTTCACC TTCCCTAACC TTACCTCCTG TGCCACCTAG 3060
CCCCACCCAA TGTCCAGATT CACCCCTGTT CAACTCACGA TGCAGTTCCC CACTCCAACT 3120
GAATCTGTTA CAACTTGAGG AGACTACCCG GGGGGAAGGG GGAGCAACAG TTGGGGAGCC 3180
TGGAAGCAAT CCCAGGCCAC CCCCTCTAGG AGAAGAGGCT ACACAACCAG AGACTGGACT 3240
GGTGGAGATG AATGAATCCT CTAACCAGGA TGCACTGTCA GGCTCCAGTG ATCTATTGGA 3300
GCTGTTGCTC CAGGAGGACT CCAGGTCTGG CACTGGATCT GCTGCATCAG GGTCCTTGGC 3360
TTCTGGTTCT GGTTCTCATG GAGGGAGCAC CTCTGCCAGT ATCACCCGTA GCAGCCAAAG 3420
CAGTCACACC AGCAAGTACT TTGGGAGTAT AGACTCCTCT GAGGCTGAGC CAACAGGTGC 3480
CCAGGTTGGG GTGGACCCAG GGACGGGACC TGGGGAGCAG GTCATTAAGT ATGTTCTGCA 3540
GGATCCCATC TGGCTACTCA TGGCTAATGC TGACCATAGG GTCATGATGA CTTATCAAGT 3600
GCCCTCCAGG GATATGGCTT CAGTACTGCA ACAGGACCGA GAGAGGCTCC GTGCCATGCA 3660
AAAGCAACAG CCTCGTTTTT CAGAAGAGCA GCGGAGAGAA CTGGGGGCCG TGCATGCCTG 3720
GGTGCGGAAG GGCCAGCTAC CTCGAGCACT AGATGTAATG GCTTGTGTAG ATTGTGGCAG 3780
CAGCATCCCA GATCCCCAGT ATCCAGATGA TTCCCTCTTC CCTGAGCTGG ATGGACTGGG 3840
GCTAGAGCCA ATGGAGGAAG ATGGAGGTGG GGCCTCCCCA GACACAGCCA TGGATGAAGA 3900
GGAGCAAGGT GGGGAGTTAT CTACTTCCGA ATTACCTGCT CTGAAAACCA ACAGCTAAAC 3960
TCTCATCTTG GGGCTACTCT GAGAGAGCCC TGGCTTTACC TCTGTCATTG AAATATGAGA 4020
AAGAACAAAT GAGAAGCTTC GTCCTCTCAA GACAACAACC AGTTCCAGTT TTGATATTTG 4080
CTTTTGCCTT TCAGTCAGCC AGGGACAAAT ACACCTGAAT ATTGTTCCTC TCTAATTGGA 4140
CAATCACAGT CCTACCTCTT TAGAGACAAC TGAGGGTAAG CAGTTGGGGC TTCTTAGGGA 4200
CCAGCCAGAG ATAAAGGTCT CCCTCTTCAT CCTAAGGAGA CAATTCCACA TAAAAAGAAG 4260
TAAAATCTTA AAAAGTAGGA TGACTTCCTA AATTCCAGCT GAGCAGGAAC ATGGATTGCT 4320
GCTTCAGGTG TGGGAACTCT AACAATACTT ATTTATTGGG GAATTCCCCC ATGTCTTCTC 4380
CTTAAAGGCC CGATTCCCTT CTCATTCCCT TGAAGGAAGG GGATGGGAAG GGAAGGGCAT 4440
TGGGAATGAG GACCAAATCG AGATTCCTAG CTCCCTTGGG TTGGAGAGAG TAGAAGACTA 4500
TGGGTCCCTG GTGCTGCTGT CTCTTAGGGT GGGACCCAGG TGTCTTCAGC TATGTCTCCC 4560
CACCCCTTAG TGATATTTTT GTGTTTTTGA TAGTCATGTC TGTCTTTTTT ATATATAAAA 4620
CAGAAAATCT AACTTGATAT TGTGGCATGA AGTCTGTTGG GGGTTAACCA GGGCTTTTCT 4680
GTCTTCACTT CAGTGGTCTT CATTTCGATT TGACAAAAAT TTAAGTATCT ATTGGGCCAG 4740
TGTTGGTGAA CATTTCAAAC TGCCTGTGAC CTCCTCCCCT CCCCCCATTA CCCCAGAAAT 4800
CGAAGGGAGG AAGTGCTTAT ATTCAGCTTC TAGGCAGAGG GGCAGGGAAT GTGAAAAATG 4860
CCCTCAGGTG CTTTGCCAAC ATGGTACTAG ACAGATACTT TAGAGATTAT AGTCTAATTT 4920
GGGGGAGGGG TACATTCAGG GTTATAATAA CCCTGGGGCT GGCAGGGGCT TGTTGAGTTT 4980
ACAGCTGCCT AGAGAAGAGT ATGGGGGTAA AATATGGACC ATGGAAAAAA CTGGATTATA 5040
AATCCTAGTA TTTATAGATT GCCAAAACTG GAAAAACCCT GAGATTCTTC TCTCCTCCAT 5100
TTTATGAATA TAGAAACTGA GGCCCAGGGA GTAAGTGATT TGCTGAAGGC AACACAGGAA 5160
GAACTGAGAT TATAACCTCA GTCCAGTACC CCCTTCCTGA CCACACTAAG CATAAACAAG 5220
TGACTAGGAT CTAGGCTCTT TTCTCTGCTT CTATTGGAAT AGGTAGCTAG CATAATTGCA 5280
AGCTGGAAGA GAGAGGAGAC CTGCCCTCAA GCAACCTCCT ACCTTCCTTT CTTAACAGAA 5340
TCTGAACTTG TACTGTCAGA TTTAACATCC ATCACATTTT CCCTGAGCCA CCAGAAGCCA 5400
GGGCCTTTCC ATTGCAAGGT GGGCTTTCCT TCTGGGTTCC AAGTCCATTA TTGAATCATC 5460
CCAATGCTAG GCTACCTTTT TTTCTGAATC CCTCACTCAA ACATGAAAAT TACGCTGAAC 5520
TTGCCCTTTC TTACCACCAC CACTCTCAGA TTGACACCTG CTAACTTTGG AGAGGAGGGT 5580
TTCAGCAGGC TGCAAAGGCC TATTGGATTC TGCCCCAGAG TGGGTCAGGA AATCCACTAC 5640
GAAACAGTCT GTGGTGTGAG CCTTTGAAGA CCAGGGCAGG CAGGGAGAGT GGAATTCTCA 5700
TTTAATGTGA TAGTAGATGT AGTCGACAGG GGAACCTATG GAAGAAAAAA GTAGAGGAGA 5760
GGGAGGGGGA TGGAAGTAAT GACCCTATGT CTCATTAAAC TGGAAATGAA GCTCTCCCCT 5820
ACAGAGAGAT AGGAGCTTTG CAAAGGGACC AACCTGGTTA CCATTATTTG GGTGCAAAAA 5880
CAGCTTTAGT AAATTCCAGC CATATGTAAG GCACTGTTAA GCTCATTCAA GCTCCTTGGA 5940
AACGTCAGCT GCGGTCCTTC CTAAAGATCC AATTTGCAAA ATGATTTTTT CCCCTCTATA 6000
AGTTGTGGCC AATGTGGCTG CTTAAGAAAC AGCAGTTCCA GAATTCGAAT TCCGGTGGTG 6060
CCTCCGATTT ATCACTGTGG AGTAACTGCA CCCTGAGGTC AACCTGAGAG GGGCAGGGAC 6120
CCCTCAACTC CCGCTCTAGT GGGTGGGTTC AGTTCATTTA TACTATACAA ATCCCATCCT 6180
TTTCACGTCC GTGAGGAGCT AAATCTATGA GAATCACAGT CCCAGGCCCA GTGAGGGGAA 6240
CTAGGGAAAG CGAAGGGCAG GATACAAATT TCTGAGCTTC CGAGGCTGTC CGTTGTCATG 6300
GCAATTTTTG CGTTTGCGCG TGCGCGTGCA TACATTCCGC CCCACAACAA CACCCTCGCT 6360
CCTCGTTGTT CCCCTCATTG CCCTGGGAAC GCGATGCGGA TTGGGGCGCT GAAGGATATT 6420
GGAAGTGGTG GGCTGGGCTG GGTGCCTGCA AAGTATTTAT GATGAAGCTG AGAGAGGACC 6480
ACAG 6484
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus61.33 0.00e+00 1419.8
CGD-GaG-021834Gallus gallus37.9 0.00e+00 746.1
CGD-HoS-021038Homo sapiens (Human)60.33 0.00e+00 1408.7
CGD-OvA-022197Ovis aries60.05 0.00e+00 1383.2
CGD-RaN-021793Rattus norvegicus61.48 0.00e+00 1393.6
Gene Ontology

GO:0005515--protein binding
GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0097167--circadian regulation of translation
GO:0043153--entrainment of circadian clock by photoperiod
GO:0009416--response to light stimulus
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0042752--regulation of circadian rhythm
GO:0002028--regulation of sodium ion transport
GO:0031490--chromatin DNA binding
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0051591--response to cAMP
GO:0070932--histone H3 deacetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0000989--transcription factor activity, transcription factor binding
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0045892--negative regulation of transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0005634--nucleus