CGDB Gene Information

Tag Content
CGDB ID CGD-IcT-062043
Ensembl Accession ENSSTOP00000004804.2
Protein Name PER1
Ensembl Information ENSSTOG00000005366; ENSSTOT00000005363
Organism Ictidomys tridecemlineatus
NCBI Taxa ID 43179
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 FSNFRNTSST SLTSQASRPP CSTVVASAPS LFSCPSHGPD MSDPLEEADG GRDPRPGESF 60
RPGGVPSPGP PQHRPCPGPN LADDTDANSN GSSGNESNGH ESRGASQRSS HSSSSGNGKD 120
SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS TSGCSSEQSA RARTQKELMT 180
ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE YYQQWSLEEG EPCAMDISTY 240
TLEELEHITS EYTLRNQDTF SVAVSFLTGR IVYISEQAGV LLRCKRDVFR GARFSELLAP 300
QDVGVFYGST APSRLPTWGT GASAGSGVKD FTQEKSVFCR IRGGPDRDPG PRYQPFRLTP 360
YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF TTRHTPSCLF QDVDERAAPL 420
LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF DHSPIRFCAR NGEYVTMDTS 480
WAGFVHPWSR KVAFVLGRHK VRTGPLNEDV FTPPAPSPTL SLDSDIQELS EQIHRLLLQP 540
VHSSSPTGLC GVGPLMSPGP LHSPGSSSDS NGGDAEGPGP PVPVTFQQIC KDVHLVKHQG 600
QQLFIESRAR PLPQPRLPAT GTFKTKALPC QTPDPELEAA PALTQAPPPL VPEEAERKEA 660
SSCSYQQINC LDSILRYLES CNIPSTTKRK CASSSSYTAS SASDDDKQRT VPIGAKKDPS 720
SAVLSGEGAA PRKEPVVGST LSPLALANKA ESVVSVTSQC SFSSTIVHVG DKKPPESDII 780
MMEELPGLAP GPTPSPAPSP TVAPDPAPDA YRPVGLTKAV LSLHTQKEEQ AFLNRFRDLG 840
RLRGLDNSST APSAPGCHHG PAPPSRRHHC RSKAKRSRHH QTPRAEAPCY VSHPSPVPPS 900
GPWPPPPATT PFPAVVQPYP LPVFSPRESP QPIPPAPTSV PSATFPTPLV TPMVALVLPN 960
YLFPTTSSYP FGVPQTPAEG PPTPASHSPS PSLPPLPPSP PRRPDSPLFN SRCSSPLQLN 1020
LLQLEEPPRP EGGTVAGGPG SSAGLPPPSE EAAEPEARLV EVTESSNQDA LSGSSDLLEL 1080
LLQEDSRSGT GSAASGSLGS GLGSGSGSGS HEGGSTSASI TRSSQSSHTS KYFGSIDSSE 1140
AEAGAAQARA EPGDQVIKYV LQDPIWLLMA NADQRVMMTY QVPSRDMASV LKQDRERLRA 1200
MQKQQPRFSE DQRRELGAVH SWVRKGQLPR ALDVMACVDC GSSSQDPGHS DDPLFSELDG 1260
LGLEPMEEGG GEGGSSGGGG DGDGGIGEGG EEAQAQVEAK VSSSQDSAME EEEQGGSSSS 1320
PALCAAENGT S 1331
Nucleotide Sequence
(Fasta)		 GTTCGGCTCG TTTTCTAGCT CTGCGGTCTT GGAGTCCCAG ACCGACTTGG AACTTGATGG 60
GAACTTGGGA ATGGGAAAGG TCCAGGTATT GGTCCATAGC CATAGGTCTG TCTAGTCGAC 120
TGCTCAGGCT CTGTTTACCC ACGCCATAAT GGCTAGGGAA GTGGAGCGTA GTCTTGACTC 180
TTTCCACCTG TAGCACCCGT ATGGGGATAG GAAACAGAAA TATCTTGCCC GCCCCCATTG 240
GGAGCCCCAG GCAGGGGAGG GTCGCATAAT GTCAGAATTC TATGATGTTA ATAGTCCAGC 300
TTTCTCCAAA CCTTTCTTCC GGTTCTTCCC CTTCAGGTAC TGGCTGTGAA CGAACTTCTC 360
AAACTTCAGA AACACTTCTT CCACCTCACT CACAAGCCAG GCCTCAAGGC CACCTTGTTC 420
AACCGTTGTG GCCTCTGCAC CTTCCCTGTT CTCCTGTCCT TCCCATGGCC CAGACATGAG 480
TGATCCCCTA GAAGAGGCTG ATGGGGGAAG GGACCCCAGG CCCGGCGAAT CCTTTCGTCC 540
TGGGGGAGTC CCATCCCCTG GACCCCCACA GCACCGGCCT TGCCCAGGCC CCAATCTGGC 600
TGATGACACT GATGCCAATA GCAATGGCTC AAGTGGCAAT GAGTCCAATG GGCATGAATC 660
CAGGGGTGCA TCTCAACGGA GTTCACATAG CTCCTCCTCT GGCAATGGCA AGGACTCGGC 720
CCTTCTGGAG ACCACTGAGA GCAGCAAGAG CACAAACTCT CAGAGCCCAT CCCCACCCAG 780
CAGTTCCATT GCCTACAGCC TCCTGAGTGC CAGCTCAGAG CAGGACAACC CATCTACCAG 840
TGGCTGCAGC AGTGAACAGT CAGCTCGGGC AAGGACTCAG AAGGAACTCA TGACTGCACT 900
TCGGGAGCTC AAGCTTCGAC TACCACCAGA GCGTCGGGGC AAAGGCCGTT CTGGGACCCT 960
GGCCACACTA CAGTATGCAC TGGCTTGTGT CAAGCAGGTG CAGGCCAACC AGGAATACTA 1020
CCAGCAGTGG AGTCTGGAGG AGGGTGAGCC ATGTGCCATG GACATATCCA CTTACACCCT 1080
GGAGGAGCTG GAGCACATCA CATCTGAGTA TACACTTCGC AACCAGGATA CCTTCTCGGT 1140
GGCTGTCTCC TTCCTGACAG GCCGAATTGT ATACATTTCG GAGCAGGCAG GAGTTCTGCT 1200
GCGTTGCAAG CGGGATGTAT TTCGGGGTGC CCGCTTCTCA GAGCTCCTGG CTCCCCAGGA 1260
TGTGGGTGTC TTCTATGGCT CCACGGCCCC ATCTCGTCTA CCCACTTGGG GCACTGGGGC 1320
CTCTGCAGGT TCAGGCGTCA AGGATTTTAC CCAGGAGAAG TCTGTTTTCT GCCGTATCAG 1380
AGGAGGTCCT GACAGAGATC CAGGGCCTCG GTATCAACCA TTCCGCCTAA CTCCATATGT 1440
GACCAAGATC CGGGTCTCAG ATGGGGCCCC TGCGCAGCCG TGCTGCTTGC TCATTGCAGA 1500
ACGCATCCAC TCGGGTTATG AAGCTCCCCG TATCCCCCCT GACAAGAGGA TTTTCACCAC 1560
ACGTCACACA CCAAGCTGCC TCTTCCAGGA CGTGGATGAA AGGGCTGCTC CGCTGCTGGG 1620
CTACCTACCC CAGGACCTCC TGGGGGCCCC AGTGCTTTTG TTCCTGCATC CCGAGGACAG 1680
ACCACTCATG CTGGCCATCC ATAAGAAGAT CCTACAGCTG GCAGGCCAAC CCTTTGACCA 1740
CTCCCCTATT CGCTTCTGTG CCCGTAATGG GGAGTACGTC ACCATGGACA CCAGCTGGGC 1800
TGGCTTCGTG CACCCCTGGA GCCGTAAGGT GGCCTTTGTG TTGGGCCGCC ACAAAGTACG 1860
CACGGGACCC CTGAATGAGG ATGTGTTCAC TCCTCCGGCT CCCAGTCCAA CTCTGTCCCT 1920
GGACTCTGAT ATCCAGGAGC TCTCAGAGCA GATCCATCGG CTACTGTTGC AGCCTGTGCA 1980
CAGCTCCAGC CCCACAGGAC TCTGTGGAGT TGGCCCCTTG ATGTCCCCAG GCCCTCTCCA 2040
CAGCCCTGGC TCTTCCAGTG ATAGCAATGG CGGTGATGCT GAGGGGCCTG GACCACCTGT 2100
TCCAGTGACT TTCCAGCAGA TCTGTAAGGA TGTGCATCTG GTGAAGCACC AGGGGCAGCA 2160
GCTTTTCATT GAGTCCCGGG CCCGGCCTCT ACCCCAGCCT CGCCTCCCTG CTACAGGCAC 2220
ATTCAAGACC AAGGCCCTTC CTTGCCAGAC CCCAGACCCA GAGCTGGAGG CAGCCCCTGC 2280
TCTGACCCAG GCTCCACCAC CCTTGGTCCC TGAGGAGGCT GAGAGGAAAG AAGCCTCCAG 2340
CTGTTCCTAT CAGCAGATCA ACTGCCTAGA CAGCATCCTC AGGTACCTGG AAAGCTGCAA 2400
CATCCCCAGC ACAACCAAGC GTAAATGCGC TTCCTCCTCC TCCTATACTG CCTCCTCAGC 2460
CTCTGATGAT GACAAGCAGA GGACAGTCCC CATAGGGGCC AAGAAAGATC CATCATCAGC 2520
AGTGCTGTCT GGGGAGGGGG CCGCTCCACG GAAGGAGCCA GTGGTGGGAA GCACCTTGAG 2580
CCCGCTCGCC CTGGCCAATA AGGCGGAGAG CGTGGTGTCC GTGACCAGTC AGTGTAGCTT 2640
CAGCTCCACC ATCGTCCATG TGGGAGACAA GAAGCCCCCG GAGTCGGACA TCATCATGAT 2700
GGAGGAACTG CCTGGCCTAG CTCCAGGCCC AACCCCCAGC CCGGCCCCCA GCCCCACAGT 2760
AGCCCCTGAC CCAGCCCCAG ATGCCTACCG CCCAGTGGGC CTGACCAAGG CCGTGCTGTC 2820
CCTGCACACA CAGAAGGAAG AGCAAGCCTT CCTCAACCGC TTCCGAGACC TTGGCAGGCT 2880
GCGTGGACTT GACAACTCTT CCACGGCCCC CTCGGCCCCT GGCTGCCACC ATGGCCCAGC 2940
ACCCCCCAGC CGCCGACACC ACTGCCGATC CAAAGCCAAG CGCTCACGCC ACCACCAGAC 3000
CCCACGGGCC GAAGCCCCCT GCTATGTCTC CCACCCCTCA CCTGTGCCCC CCTCTGGCCC 3060
CTGGCCCCCT CCTCCAGCCA CCACTCCCTT CCCAGCAGTG GTCCAGCCTT ACCCACTCCC 3120
AGTGTTCTCC CCACGGGAAA GTCCCCAGCC TATTCCTCCT GCTCCCACAT CTGTGCCCTC 3180
TGCCACTTTC CCTACCCCCT TAGTAACTCC AATGGTGGCC TTGGTGCTCC CTAACTATCT 3240
GTTCCCGACT ACATCTAGCT ATCCCTTTGG GGTACCTCAG ACACCAGCTG AGGGGCCTCC 3300
TACCCCTGCC TCCCACTCAC CCTCCCCATC CCTGCCCCCA CTTCCTCCCA GTCCCCCACG 3360
CCGCCCAGAC TCCCCACTGT TCAACTCAAG ATGCAGTTCC CCACTCCAGC TCAATCTGCT 3420
GCAACTTGAG GAGCCCCCCC GTCCTGAGGG GGGCACTGTT GCAGGGGGTC CTGGGAGCAG 3480
TGCTGGGCTC CCACCTCCTA GTGAGGAGGC CGCTGAGCCT GAAGCCAGAT TGGTGGAGGT 3540
AACTGAATCC TCCAATCAGG ATGCACTCTC TGGCTCCAGT GATCTGTTGG AACTGCTACT 3600
GCAAGAGGAC TCGCGTTCTG GTACAGGCTC TGCAGCCTCA GGCTCCCTTG GCTCTGGCTT 3660
GGGCTCTGGA TCAGGTTCAG GCTCCCATGA GGGTGGCAGC ACCTCAGCCA GCATCACCCG 3720
CAGCAGTCAG AGCAGCCACA CAAGCAAGTA CTTCGGCAGC ATTGACTCTT CGGAAGCTGA 3780
AGCTGGAGCT GCTCAGGCCA GGGCTGAGCC TGGGGACCAG GTCATTAAGT ATGTGCTCCA 3840
GGATCCCATC TGGCTGCTTA TGGCCAATGC TGACCAACGT GTTATGATGA CCTACCAGGT 3900
GCCCTCCAGG GACATGGCAT CTGTGCTAAA GCAGGACCGA GAGCGGCTCC GAGCCATGCA 3960
GAAGCAGCAG CCTCGGTTCT CAGAGGACCA GCGGCGGGAA CTGGGTGCTG TGCACTCCTG 4020
GGTCCGCAAG GGACAGTTGC CTCGGGCCCT TGATGTGATG GCCTGTGTGG ACTGTGGTAG 4080
CAGCTCCCAA GACCCTGGCC ACTCTGATGA CCCACTTTTC TCGGAGCTGG ATGGACTGGG 4140
GCTGGAGCCC ATGGAGGAGG GTGGAGGCGA GGGTGGCAGC AGTGGTGGTG GTGGTGATGG 4200
TGATGGTGGC ATTGGTGAGG GTGGCGAGGA GGCCCAGGCC CAAGTTGAGG CCAAGGTCTC 4260
AAGCTCTCAG GACTCTGCCA TGGAGGAGGA GGAACAAGGT GGGAGCTCGT CCAGTCCAGC 4320
CTTATGTGCA GCAGAAAATG GCACCAGCTA A 4351
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus62.58 0.00e+00 1515.4
CGD-HoS-021038Homo sapiens (Human)62.81 0.00e+00 1512.3
CGD-OvA-022197Ovis aries64.27 0.00e+00 1459.1
CGD-RaN-021793Rattus norvegicus64.7 0.00e+00 1484.9
Gene Ontology

GO:0005737--cytoplasm
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0031625--ubiquitin protein ligase binding
GO:0007623--circadian rhythm
GO:0043967--histone H4 acetylation
GO:0032922--circadian regulation of gene expression
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:0019900--kinase binding
GO:0043966--histone H3 acetylation
GO:0005634--nucleus
GO:0005515--protein binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation