CGDB Gene Information

Tag Content
CGDB ID CGD-BoT-054337
Ensembl Accession ENSBTAP00000005076.4
Protein Name PER1
Ensembl Information ENSBTAG00000003889; ENSBTAT00000005076
Organism Bos taurus
NCBI Taxa ID 9913
Circadian Information
Phase Amplitude
(FOLD)		 Tissue/Cell Evidence
Peak Trough External
condition
CT 0 CT 12 DD2 5.8 gluteal muscles Predicted from orthologs F7AU00
ZT 21 ZT 9 LD 6 duodenum Predicted from orthologs Q8QGQ8
ZT 2 ZT 18 LD 3.17 embryos Predicted from orthologs Q8QGQ8
ZT 6 ZT 18 LD 8 embryos Predicted from orthologs Q8QGQ8
CT 12 CT 0 DD1 3 granulosa cells Predicted from orthologs Q8QGQ8
ZT 3 ZT 18 LD 84.29 pineal glands Predicted from orthologs Q8QGQ8
ZT 23 ZT 11 LD 2.25 spleen Predicted from orthologs Q8QGQ8
ZT 4 ZT 21 LD 2 human HaCaT keratinocytes Predicted from orthologs O15534
CT 0 CT 12 DD2 4 U2OS cells Predicted from orthologs O15534
ZT 0 ZT 12 LD 2 muscle Predicted from orthologs W5QC67
ZT 4 ZT 0 LD 5 SCN Predicted from orthologs W5QC67
ZT 12 ZT 0 LD 30 abdominal adipose tissue Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 11 basolateral nucleus of the amygdala Predicted from orthologs Q8CHI5
CT 12 CT 20 DD17 6.25 colon Predicted from orthologs Q8CHI5
ZT 18 ZT 6 LD 2 decidua Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3.5 entral nucleus of the amygdala Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 8 hippocampus Predicted from orthologs Q8CHI5
ZT 9 ZT 0 LD 48 intestinal jejunal mucosa Predicted from orthologs Q8CHI5
CT 12 CT 0 DD17 16.67 liver Predicted from orthologs Q8CHI5
ZT 16 ZT 4 LD >5 mammary gland (pubescent female F344 rats) Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 8 nucleus accumbens core Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 7 nucleus accumbens shell Predicted from orthologs Q8CHI5
CT 20 CT 0 DD1 1.71 PC12 cell Predicted from orthologs Q8CHI5
ZT 0 ZT 16 LD 7.5 prefrontal cortex Predicted from orthologs Q8CHI5
ZT 4 ZT 16 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 20 ZT 8 LD 15 SCN Predicted from orthologs Q8CHI5
ZT 4 ZT 20 LD 3 SCN Predicted from orthologs Q8CHI5
ZT 8 ZT 0 LD 4.76 uteri Predicted from orthologs Q8CHI5
ZT 8 ZT 20 LD 7 ventral tegmental area Predicted from orthologs Q8CHI5
Descriptionperiod circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845](View all)
Protein Sequence
(Fasta)		 RSGPLEGAEG GGDPRPGEPF CPGGGPSPGP PEHRPCPGPS LADDTDANSN GSSGNESNGP 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEPDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
FYQQWSLEEG EPCAMDMSTY TLEELEHVTS EYTLRNQDTF SVAVSFLTGR IVYISEQAGV 240
LLRCKRDVFR GARFSELLAP QDVGVFYGST TPSRLPTWGP GTSAGSGLKD FTQEKSVFCR 300
IRGGPDRDPG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPVPSPAL 480
SLDSDIQELS EQIHRLLLQP VHSPSPTGLC GVGPVPSSGP LLSPGSSSDS NGGDAEGPGP 540
PAPVTFQQIC KDVHLVKHQG QQLFIESRAR PLPRPRVPAT GTFKAKTLPC QSPDLEAAPA 600
PIQAPVALAA EDAERKEASS CSYQQINCLD SILRYLESCN LPSTAKRKCA SSSSCTASSA 660
SDDDKQRAGP VSVGAKKDPS AVLPGEGATP LKEPVVGGGA LSPLALANKA ESVVSITSQC 720
SFSSTIVHVG DKKPPESDII MMEDLPSLPP GPAPSPAPSP TVAPDPAPDA YRPVGLTKAV 780
LSLHTQKEEQ AFLSRFRDFS RLRGLDSSST APSAPGERGC HHSLAIPGRR HHCRSKAKRS 840
RHHQTTRAEA PGYISQPSPV PPSAPWPPPP ATPPFPAVVQ PYPLPVFPPR GGSQPLPPAP 900
TSVPPAAFPA PLVTPMVALV LPNYLFPTPS TYPYGAPQMP AEGPPTPASR SPSPSLPPSP 960
PHRSDSPLFN SRCSSPLQLN LLQLEEAPRG EGGAAAAGSG SSAGHPPPSE ETAEPEARLA 1020
EVTESSNQDA LSGSSDLLEL LLQEDSRSGT GSAASGSLAS GLGSGSGSHE GGSTSASITR 1080
SSQSSHTSKY FGSIDSSEAE AGAAQARAEP GDQVIKYVLQ DPIWLLMANA DQRVMMTYQV 1140
PSSRDMASVL KQDRERLRAM QKQQPRFSED QRRELGAVHS WVRKGQLPRA LDVMACVDCG 1200
SSTQEPGHPD DPLFSEVDGL GLEPMEEGGG EGGGGGGEGE GSDEAQAQAG ARVSSSQDLA 1260
MEEEEQGGSS PSPALPATEN GTS 1283
Nucleotide Sequence
(Fasta)		 AGGAGCGGCC CCCTAGAAGG GGCTGAAGGG GGAGGGGACC CCAGGCCAGG GGAACCCTTT 60
TGTCCTGGAG GGGGTCCATC CCCTGGGCCT CCAGAGCACC GACCTTGTCC TGGCCCCAGC 120
TTGGCTGATG ACACGGATGC CAACAGCAAT GGCTCTAGCG GCAATGAGTC CAATGGACCC 180
GAGTCCAGGG GTGCATCTCA GCGGAGTTCG CACAGCTCCT CCTCCGGCAA TGGCAAGGAC 240
TCAGCTCTGC TGGAGACCAC TGAGAGCAGC AAGAGCACGA ACTCTCAGAG CCCATCCCCA 300
CCCAGCAGTT CTATTGCCTA TAGCCTCCTG AGTGCCAGCT CTGAGCCAGA CAACCCTTCT 360
ACCAGTGGCT GCAGCAGTGA ACAGTCAGCT CGGGCAAGGA CTCAGAAAGA ACTCATGACG 420
GCACTGCGAG AGCTCAAGCT TCGGCTGCCC CCGGAGCGCA GGGGCAAGGG CCGCTCCGGG 480
ACTCTGGCCA CACTGCAGTA CGCGCTGGCC TGTGTCAAGC AGGTGCAAGC CAACCAGGAG 540
TTCTACCAGC AATGGAGCCT GGAGGAGGGC GAACCGTGTG CCATGGACAT GTCCACCTAT 600
ACTCTGGAGG AGCTGGAGCA CGTCACATCT GAGTACACAC TCCGCAACCA GGACACCTTC 660
TCCGTGGCTG TCTCCTTCCT GACAGGCCGC ATCGTCTACA TTTCCGAGCA GGCGGGTGTC 720
CTGCTGCGCT GCAAGCGGGA CGTGTTCCGG GGTGCCCGCT TCTCTGAGCT TTTGGCTCCC 780
CAGGACGTGG GCGTCTTCTA CGGTTCCACC ACCCCATCCC GCCTGCCCAC CTGGGGCCCA 840
GGGACCTCTG CAGGTTCAGG CCTCAAGGAC TTCACCCAGG AGAAGTCTGT CTTCTGTCGT 900
ATCAGAGGGG GTCCTGACCG GGATCCGGGG CCTCGGTACC AGCCATTCCG CCTAACCCCA 960
TATGTGACCA AGATCCGGGT CTCCGACGGG GCCCCTGCCC AGCCATGCTG CCTGCTCATC 1020
GCAGAGCGCA TTCACTCTGG TTATGAAGCT CCCCGGATCC CCCCTGACAA GAGGATCTTC 1080
ACCACACGAC ACACGCCCAG CTGCCTCTTC CAGGATGTGG ATGAGAGGGC TGCCCCGCTG 1140
CTAGGCTACC TCCCCCAGGA CCTCCTGGGG GCCCCAGTGC TCCTCTTCCT GCATCCGGAG 1200
GACCGACCCC TCATGCTGGC CATTCACAAG AAGATCCTGC AGCTGGCCGG CCAGCCCTTT 1260
GACCACTCCC CTATTCGCTT CTGTGCCCGT AATGGGGAGT ACGTCACCAT GGACACCAGC 1320
TGGGCTGGTT TCGTGCACCC CTGGAGCCGC AAGGTGGCCT TTGTGTTGGG CCGCCACAAA 1380
GTACGCACGG CGCCCCTGAA TGAAGATGTA TTCACTCCCC CGGTCCCCAG CCCTGCTCTG 1440
TCCCTGGACT CTGACATCCA AGAGCTCTCA GAGCAGATCC ACCGGCTGCT GTTACAGCCT 1500
GTGCACAGCC CCAGCCCCAC GGGCCTCTGT GGAGTAGGCC CCGTGCCTTC CTCTGGCCCT 1560
CTCCTCAGCC CTGGCTCCTC CAGTGACAGC AATGGGGGTG ATGCCGAGGG ACCTGGGCCT 1620
CCTGCCCCGG TGACCTTCCA GCAGATCTGT AAGGATGTGC ACCTGGTGAA GCATCAGGGG 1680
CAGCAGCTTT TTATTGAGTC CCGGGCCCGG CCTCTGCCCC GGCCCCGTGT CCCTGCTACT 1740
GGCACATTCA AGGCCAAGAC CCTTCCCTGC CAATCCCCAG ACCTGGAGGC GGCCCCGGCT 1800
CCAATCCAGG CCCCAGTGGC CTTGGCCGCT GAGGATGCTG AGCGGAAAGA AGCCTCCAGT 1860
TGCTCCTACC AGCAGATCAA CTGCCTGGAC AGCATCCTCA GGTACCTGGA GAGCTGCAAC 1920
CTCCCCAGCA CCGCAAAGCG CAAATGTGCG TCCTCCTCTT CCTGCACTGC CTCTTCGGCC 1980
TCCGACGACG ACAAGCAGCG GGCAGGCCCA GTCTCTGTGG GCGCCAAGAA AGATCCATCA 2040
GCAGTGCTGC CTGGGGAGGG GGCCACCCCT CTGAAGGAGC CGGTGGTGGG AGGAGGAGCC 2100
CTGAGCCCAC TCGCCCTGGC CAATAAGGCG GAGAGCGTGG TGTCCATCAC CAGTCAGTGT 2160
AGCTTCAGCT CCACCATCGT CCATGTGGGA GACAAGAAGC CCCCGGAGTC GGACATCATC 2220
ATGATGGAGG ACCTGCCCAG CCTGCCTCCT GGTCCAGCTC CCAGCCCAGC CCCTAGTCCT 2280
ACGGTAGCCC CTGACCCAGC CCCAGACGCC TACCGCCCAG TGGGCCTGAC CAAGGCCGTG 2340
CTGTCCCTGC ACACACAGAA GGAGGAGCAG GCCTTCCTCA GCCGCTTCCG TGACTTCAGC 2400
AGGCTGCGTG GACTGGACAG CTCCTCCACA GCCCCCTCGG CCCCTGGCGA GCGAGGCTGC 2460
CACCACAGCC TTGCCATCCC CGGCCGCCGC CACCACTGCC GATCCAAAGC CAAGCGCTCA 2520
CGTCACCACC AGACAACTCG GGCCGAAGCC CCCGGCTACA TCTCCCAGCC CTCGCCTGTG 2580
CCACCCTCTG CCCCCTGGCC CCCGCCACCA GCCACTCCTC CCTTCCCAGC TGTGGTCCAG 2640
CCATACCCAC TCCCCGTGTT CCCCCCGAGA GGTGGCTCTC AGCCTCTCCC TCCTGCTCCC 2700
ACGTCTGTGC CTCCTGCAGC TTTCCCTGCC CCCCTGGTGA CCCCCATGGT GGCCTTGGTG 2760
CTCCCTAACT ATCTGTTCCC TACCCCATCC ACCTACCCCT ACGGGGCACC CCAGATGCCT 2820
GCTGAGGGGC CTCCTACCCC TGCCTCCCGC TCCCCGTCTC CGTCCCTGCC CCCGAGCCCT 2880
CCCCACCGCT CCGACTCTCC GCTCTTCAAC TCAAGATGCA GCTCCCCACT CCAGCTAAAC 2940
CTGCTGCAGC TTGAGGAGGC CCCTCGAGGT GAGGGGGGTG CAGCGGCAGC GGGCTCTGGG 3000
AGCAGTGCTG GGCACCCCCC TCCCAGCGAG GAGACGGCAG AACCAGAGGC CAGACTGGCG 3060
GAGGTAACTG AGTCCTCCAA CCAGGATGCT CTCTCGGGCT CCAGTGACCT GCTGGAGTTG 3120
CTGCTACAAG AGGACTCTCG ATCAGGCACG GGCTCTGCTG CCTCAGGCTC CTTGGCCTCC 3180
GGCTTGGGCT CTGGTTCAGG CTCCCATGAG GGGGGCAGCA CTTCCGCCAG CATCACGCGC 3240
AGCAGTCAGA GCAGCCACAC GAGCAAGTAC TTTGGCAGCA TCGATTCTTC AGAGGCTGAG 3300
GCTGGGGCTG CCCAGGCCAG GGCTGAGCCT GGGGACCAGG TCATTAAGTA TGTGCTCCAG 3360
GATCCCATCT GGCTGCTCAT GGCCAATGCT GACCAGCGTG TCATGATGAC TTATCAGGTG 3420
CCCTCCAGCA GGGACATGGC CTCTGTGCTG AAGCAGGACC GGGAGCGGCT CCGGGCCATG 3480
CAGAAGCAGC AGCCTCGGTT CTCGGAGGAC CAGCGGAGGG AACTGGGTGC TGTGCACTCC 3540
TGGGTCCGGA AAGGTCAACT GCCTCGGGCC CTTGATGTGA TGGCCTGTGT GGACTGCGGT 3600
AGCAGCACCC AAGAGCCTGG CCATCCTGAT GACCCTCTCT TCTCGGAAGT GGATGGACTG 3660
GGGCTGGAGC CCATGGAGGA GGGCGGAGGC GAGGGTGGTG GCGGTGGTGG TGAGGGTGAG 3720
GGCAGCGATG AGGCCCAGGC CCAAGCTGGG GCCAGGGTCT CGAGCTCTCA GGACCTGGCC 3780
ATGGAAGAGG AGGAGCAAGG TGGGAGCTCA CCCAGTCCAG CCTTACCTGC CACAGAAAAT 3840
GGCACCAGCT AGACTCCATT TTGGGCCA 3868
Sequence Source Ensembl
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-EqC-020994Equus caballus62.74 0.00e+00 1469.1
CGD-GaG-021834Gallus gallus41.31 1.00e-172 604.4
CGD-HoS-021038Homo sapiens (Human)62.9 0.00e+00 1490.7
CGD-OvA-022197Ovis aries65.42 0.00e+00 1560
CGD-RaN-021793Rattus norvegicus63.15 0.00e+00 1419.8
Gene Ontology

GO:0005515--protein binding
GO:0043966--histone H3 acetylation
GO:0019900--kinase binding
GO:0070888--E-box binding
GO:0042634--regulation of hair cycle
GO:0032922--circadian regulation of gene expression
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0031625--ubiquitin protein ligase binding
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005737--cytoplasm
GO:0005634--nucleus
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0051591--response to cAMP
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0042752--regulation of circadian rhythm
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation