CGDB Gene Information

Tag Content
CGDB ID CGD-MuM-031636
Ensembl Accession ENSMUSP00000021271.7
Protein Name Per1
Ensembl Information ENSMUSG00000020893; ENSMUST00000021271
Organism Mus musculus (Mouse)
NCBI Taxa ID 10090
Circadian Information
Evidence Phase Amplitude
(FOLD)		 Sentence Tissue/Cell Data type PMID
Peak Trough External
condition
High-throughput CT 9 CT 3 DD2 6.29 Identified over 3,000 different transcripts in the mouse liver that cycle with a period length of approximately 24 hours. liver Microarray [1]
High-throughput CT 14 CT 2 DD2 22.60 Robust transcript oscillations often accompanied rhythms in multiple histone modifications and recruitment of multiple chromatin-associated clock components.? liver RNA-seq [1]
High-throughput CT 13 CT 1 DD1 64.42 CLOCK-dependent direct transactivation through multiple E-boxes and indirect regulations polyphonically orchestrate dynamic circadian outputs. liver RNA-seq [1]
High-throughput ZT 10 ZT 22 LD 10.05 The dynamics of translational regulation, circadian gene expression, and metabolic control in a solid mammalian organ. liver RNA-seq [1]
High-throughput ZT 8 ZT 20 LD 7.79 This study provides an important chronobiological resource (www.wgpembroke.com/shiny/SCNseq/) and allows us to propose that transcriptional timing in the SCN is gating clock resetting mechanisms. SCN RNA-seq [1]
Descriptionperiod circadian clock 1 [Source:MGI Symbol;Acc:MGI:1098283](View all)
Protein Sequence
(Fasta)		 MSGPLEGADG GGDPRPGEPF CPGGVPSPGA PQHRPCPGPS LADDTDANSN GSSGNESNGP 60
ESRGASQRSS HSSSSGNGKD SALLETTESS KSTNSQSPSP PSSSIAYSLL SASSEQDNPS 120
TSGCSSEQSA RARTQKELMT ALRELKLRLP PERRGKGRSG TLATLQYALA CVKQVQANQE 180
YYQQWSLEEG EPCAMDMSTY TLEELEHITS EYTLRNQDTF SVAVSFLTGR IVYISEQAGV 240
LLRCKRDVFR GARFSELLAP QDVGVFYGST TPSRLPTWGT GTSAGSGLKD FTQEKSVFCR 300
IRGGPDRDPG PRYQPFRLTP YVTKIRVSDG APAQPCCLLI AERIHSGYEA PRIPPDKRIF 360
TTRHTPSCLF QDVDERAAPL LGYLPQDLLG APVLLFLHPE DRPLMLAIHK KILQLAGQPF 420
DHSPIRFCAR NGEYVTMDTS WAGFVHPWSR KVAFVLGRHK VRTAPLNEDV FTPPAPSPAP 480
SLDSDIQELS EQIHRLLLQP VHSSSPTGLC GVGPLMSPGP LHSPGSSSDS NGGDAEGPGP 540
PAPVTFQQIC KDVHLVKHQG QQLFIESRAK PPPRPRLLAT GTFKAKVLPC QSPNPELEVA 600
PVPDQASLAL APEEPERKET SGCSYQQINC LDSILRYLES CNIPSTTKRK CASSSSYTAS 660
SASDDDKQRA GPVPVGAKKD PSSAMLSGEG ATPRKEPVVG GTLSPLALAN KAESVVSVTS 720
QCSFSSTIVH VGDKKPPESD IIMMEDLPGL APGPAPSPAP SPTVAPDPTP DAYRPVGLTK 780
AVLSLHTQKE EQAFLNRFRD LGRLRGLDTS SVAPSAPGCH HGPIPPGRRH HCRSKAKRSR 840
HHHHQTPRPE TPCYVSHPSP VPSSGPWPPP PATTPFPAMV QPYPLPVFSP RGGPQPLPPA 900
PTSVSPATFP SPLVTPMVAL VLPNYLFPTP PSYPYGVSQA PVEGPPTPAS HSPSPSLPPP 960
PLSPPHRPDS PLFNSRCSSP LQLNLLQLEE SPRTEGGAAA GGPGSSAGPL PPSEETAEPE 1020
ARLVEVTESS NQDALSGSSD LLELLLQEDS RSGTGSAASG SLGSGLGSGS GSGSHEGGST 1080
SASITRSSQS SHTSKYFGSI DSSEAEAGAA RARTEPGDQV IKCVLQDPIW LLMANADQRV 1140
MMTYQVPSRD AASVLKQDRE RLRAMQKQQP RFSEDQRREL GAVHSWVRKG QLPRALDVTA 1200
CVDCGSSVQD PGHSDDPLFS ELDGLGLEPM EEGGGEGGGC GVGGGGGDGG EEAQTQIGAK 1260
GSSSQDSAME EEEQGGGSSS PALPAEENST S 1291
Nucleotide Sequence
(Fasta)		 CGCGGAGCTT CTGGGTTGCG GGCCGAAACG GCAAGCGGAT GGAGGGCGCT CGAACGGCCA 60
GGTGTCGTGA TTAAATTAGT CAGCCCTCAG AGACAGGCGT CCTACCTCCT TTATCCAGAC 120
CTCAAAAGCC CCGTTGTGCA CCCGTGGTGG CTTCTTCACC TTCCCTGTTT CGTCCTCCAC 180
TGTATGGCCC AGACATGAGT GGTCCCCTAG AAGGGGCCGA TGGGGGAGGA GACCCCAGGC 240
CCGGAGAACC TTTTTGTCCT GGAGGAGTCC CATCCCCTGG GGCCCCGCAG CACCGGCCTT 300
GTCCAGGCCC CAGCCTGGCT GATGACACTG ATGCAAACAG CAATGGCTCA AGTGGCAATG 360
AGTCCAACGG ACCCGAGTCC AGGGGCGCAT CTCAGCGGAG TTCTCATAGT TCCTCTTCTG 420
GCAATGGCAA GGACTCAGCT CTGCTGGAGA CCACTGAGAG CAGCAAGAGT ACAAACTCAC 480
AGAGCCCATC CCCACCCAGC AGCTCCATTG CCTACAGCCT CCTGAGTGCG AGCTCAGAGC 540
AGGACAACCC ATCTACCAGT GGCTGCAGCA GTGAACAGTC AGCTCGAGCC AGGACCCAGA 600
AAGAACTCAT GACTGCACTT CGGGAGCTCA AACTTCGACT GCCACCAGAG CGTCGGGGCA 660
AGGGCCGCTC TGGGACCTTG GCCACACTGC AGTACGCTCT GGCCTGTGTC AAGCAGGTTC 720
AGGCTAACCA GGAATATTAC CAGCAGTGGA GTCTGGAGGA GGGTGAGCCT TGTGCCATGG 780
ACATGTCTAC TTACACCCTG GAGGAATTGG AGCATATCAC ATCCGAATAC ACACTTCGAA 840
ACCAGGACAC CTTCTCTGTG GCTGTGTCCT TCCTGACAGG CCGGATTGTC TATATTTCGG 900
AGCAGGCAGG TGTCCTGCTG CGTTGCAAAC GGGATGTGTT TCGGGGTGCC CGCTTCTCAG 960
AGCTCCTGGC TCCCCAGGAT GTGGGTGTCT TCTATGGCTC TACTACACCA TCTCGACTGC 1020
CCACCTGGGG CACTGGCACC TCTGCAGGTT CAGGTCTCAA GGACTTCACC CAGGAAAAGT 1080
CTGTCTTCTG CCGAATCAGA GGAGGTCCTG ACCGGGATCC AGGGCCTCGG TACCAGCCAT 1140
TCCGCCTAAC CCCATATGTG ACCAAGATTC GGGTCTCAGA TGGAGCCCCT GCACAGCCGT 1200
GCTGCCTACT CATTGCCGAG CGCATCCACT CTGGTTATGA AGCTCCCCGG ATCCCTCCTG 1260
ACAAGAGGAT CTTCACCACC CGACACACAC CAAGCTGCCT CTTCCAGGAT GTAGATGAAA 1320
GGGCTGCCCC ACTGCTGGGT TACCTTCCCC AGGATCTCCT GGGGGCTCCA GTACTTCTCT 1380
TTCTACATCC TGAGGACCGA CCCCTCATGC TGGCCATTCA TAAGAAGATA CTGCAGCTGG 1440
CAGGCCAGCC CTTTGACCAT TCCCCTATTC GCTTCTGTGC TCGGAACGGG GAATATGTCA 1500
CCATGGACAC CAGCTGGGCC GGTTTTGTGC ACCCCTGGAG CCGCAAGGTG GCTTTCGTGT 1560
TGGGTCGCCA TAAAGTGCGC ACGGCACCCC TGAATGAGGA CGTCTTCACT CCCCCAGCCC 1620
CCAGCCCAGC TCCGTCCCTG GACTCTGATA TCCAGGAGCT CTCAGAGCAG ATCCATCGAT 1680
TGCTGCTGCA GCCTGTGCAC AGCTCCAGCC CCACGGGGCT CTGTGGAGTT GGCCCTCTGA 1740
TGTCCCCTGG TCCTCTACAC AGCCCTGGCT CCTCCAGTGA TAGCAATGGG GGGGACGCTG 1800
AGGGGCCTGG GCCTCCTGCT CCAGTGACTT TCCAGCAGAT CTGTAAGGAT GTGCATCTGG 1860
TAAAGCACCA GGGACAACAG CTCTTCATTG AATCTCGGGC CAAGCCCCCA CCCCGGCCCC 1920
GCCTCCTTGC TACAGGTACA TTCAAAGCCA AAGTCCTTCC CTGCCAGTCC CCAAACCCCG 1980
AACTGGAGGT GGCCCCAGTT CCTGACCAAG CCTCGTTAGC CTTGGCCCCT GAGGAGCCAG 2040
AGAGGAAAGA AACCTCTGGC TGTTCCTACC AGCAGATCAA CTGCCTGGAC AGCATCCTCA 2100
GGTATTTGGA GAGCTGCAAC ATTCCCAGTA CAACCAAGCG TAAATGTGCC TCCTCCTCCT 2160
CCTACACTGC CTCTTCAGCC TCTGATGATG ACAAGCAGAG GGCAGGTCCA GTTCCTGTGG 2220
GGGCCAAGAA AGATCCGTCG TCAGCAATGC TGTCTGGGGA GGGGGCAACT CCTCGGAAGG 2280
AGCCAGTGGT GGGAGGCACC CTGAGCCCGC TCGCCCTGGC CAATAAGGCA GAGAGCGTGG 2340
TGTCCGTCAC CAGTCAGTGT AGCTTCAGCT CCACCATCGT CCATGTGGGA GACAAGAAGC 2400
CCCCGGAGTC GGACATCATC ATGATGGAAG ACCTGCCTGG CCTGGCCCCT GGCCCAGCCC 2460
CCAGTCCGGC CCCCAGCCCC ACAGTAGCCC CTGACCCAAC CCCAGATGCT TATCGCCCAG 2520
TGGGTCTGAC CAAGGCCGTG CTGTCCCTGC ACACACAGAA GGAAGAGCAA GCCTTCCTCA 2580
ACCGCTTCAG AGATCTTGGC AGGCTTCGTG GACTTGACAC CTCTTCTGTG GCCCCCTCAG 2640
CCCCTGGCTG CCACCATGGC CCCATTCCCC CTGGTCGCCG ACACCACTGC CGATCTAAAG 2700
CAAAGCGTTC CCGCCACCAC CACCACCAGA CCCCCCGGCC CGAAACTCCC TGCTATGTCT 2760
CCCATCCTTC ACCTGTGCCC TCTTCTGGAC CCTGGCCACC CCCACCAGCC ACGACCCCCT 2820
TCCCAGCAAT GGTCCAGCCC TACCCACTCC CAGTATTCTC CCCTCGAGGA GGACCCCAGC 2880
CCCTTCCCCC TGCCCCTACA TCTGTGTCCC CTGCTACCTT CCCTTCTCCC TTAGTGACCC 2940
CAATGGTGGC CTTGGTGCTC CCTAACTATC TATTCCCTAC CCCACCTAGT TATCCATATG 3000
GGGTGTCCCA GGCCCCTGTT GAGGGGCCAC CCACGCCTGC TTCCCACTCG CCCTCTCCAT 3060
CCCTGCCCCC ACCACCTCTC AGCCCCCCCC ACCGCCCAGA CTCCCCACTG TTCAACTCGA 3120
GATGCAGCTC CCCACTCCAG CTCAATCTGC TGCAGCTTGA GGAGTCCCCC CGCACGGAGG 3180
GGGGCGCTGC TGCAGGAGGC CCAGGAAGCA GTGCTGGGCC CCTGCCTCCC AGTGAGGAGA 3240
CTGCTGAGCC AGAGGCCAGA TTGGTGGAGG TTACTGAGTC GTCCAATCAG GATGCACTTT 3300
CAGGCTCCAG CGACCTGCTG GAGCTACTGC TCCAAGAAGA CTCTCGCTCG GGCACAGGCT 3360
CCGCAGCCTC AGGCTCCCTG GGCTCTGGCC TGGGCTCTGG GTCTGGTTCA GGATCCCACG 3420
AAGGGGGAAG CACCTCAGCC AGCATCACCC GCAGCAGTCA GAGCAGCCAT ACAAGCAAGT 3480
ACTTTGGCAG CATCGACTCT TCCGAGGCTG AAGCTGGGGC TGCTCGGGCC AGGACTGAGC 3540
CTGGGGACCA GGTCATTAAG TGTGTGCTCC AGGACCCCAT CTGGCTGCTC ATGGCCAATG 3600
CCGACCAGCG TGTCATGATG ACATACCAGG TGCCGTCCAG GGATGCAGCC TCTGTGCTGA 3660
AGCAAGACCG GGAGAGGCTC CGGGCCATGC AGAAACAGCA GCCACGGTTC TCAGAGGACC 3720
AGAGGCGGGA ACTGGGTGCT GTGCACTCCT GGGTCCGGAA GGGCCAGCTG CCTCGGGCCC 3780
TTGATGTGAC GGCGTGTGTG GACTGTGGCA GCAGCGTTCA AGATCCTGGC CACTCTGATG 3840
ACCCCCTCTT CTCAGAACTG GATGGATTGG GGCTGGAGCC CATGGAAGAG GGTGGAGGCG 3900
AGGGTGGTGG GTGTGGTGTT GGCGGTGGTG GGGGTGATGG TGGTGAGGAG GCCCAGACCC 3960
AAATTGGGGC TAAGGGTTCA AGCTCTCAGG ACTCTGCCAT GGAGGAAGAA GAGCAAGGTG 4020
GGGGCTCATC CAGCCCAGCT TTACCTGCAG AAGAAAACAG CACCAGCTAG ACTCCATTTT 4080
GGGGCCGCTT ACAGCAGTCT AATGAGAGGC TTCCTTTCGA CCATGTTGGG GTTCTTATAA 4140
CTCAAGATAC AGCTGGACCA ACCAATAGGA AACTGCCCCA GCTTCTCCCA ACATAGGGGG 4200
CTGGACCCCC ATTACCAGCC CAGGCACAGG AGCTGCCTCT AGCTTCTTAG CAGAGTGGAA 4260
GTTCTCAGCC CCATTTGGAG GATTGTCCAC GCCCGTCCCA CTGAGGAGAC GGGCGGGTCT 4320
TCGGTTAAGG TTGCTGACAA GCTGCTGAAG TGGTCTGTCC AAATCCCAGC TGAGCCTGAG 4380
TCCCAGTCGC AGGGTTGGGG CTGCACTTAT TTATTTGGGA GAGACAGCTC ACTCTCCCAC 4440
CTCACCCCAA GATGGGAGGA GGGGAACCTG GGATCTGTGT AGGATCCAGG TCCGTGAACC 4500
CCTAGCTGCT CCAGGGTGGG GGAGGTTGGT GGACCATGGA GTCCCTGGTG CTGCCCCTCA 4560
GGTGGGACCC AGGTGTTCTC AGCTCTACCC TCTACCAATG ACATTTGTGT TTTTGATATT 4620
GTGTCTGTTA TTTTTTTTTT AATACAAAAT GACAAAATGA AAAACCAAAA A 4671
Sequence Source Ensembl
Gene Ontology

GO:0005737--cytoplasm
GO:0005634--nucleus
GO:0005515--protein binding
GO:0045944--positive regulation of transcription from RNA polymerase II promoter
GO:0006351--transcription, DNA-templated
GO:0008134--transcription factor binding
GO:0045892--negative regulation of transcription, DNA-templated
GO:0005829--cytosol
GO:0000978--RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0005654--nucleoplasm
GO:0000122--negative regulation of transcription from RNA polymerase II promoter
GO:0000989--transcription factor activity, transcription factor binding
GO:0043966--histone H3 acetylation
GO:0010608--posttranscriptional regulation of gene expression
GO:0070932--histone H3 deacetylation
GO:0031625--ubiquitin protein ligase binding
GO:0019900--kinase binding
GO:0043967--histone H4 acetylation
GO:0007623--circadian rhythm
GO:0051591--response to cAMP
GO:0032922--circadian regulation of gene expression
GO:0000976--transcription regulatory region sequence-specific DNA binding
GO:0043124--negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0031490--chromatin DNA binding
GO:0002028--regulation of sodium ion transport
GO:0046329--negative regulation of JNK cascade
GO:0042752--regulation of circadian rhythm
GO:0042634--regulation of hair cycle
GO:0070888--E-box binding
GO:2000323--negative regulation of glucocorticoid receptor signaling pathway
GO:0009416--response to light stimulus
GO:0043153--entrainment of circadian clock by photoperiod
GO:0097167--circadian regulation of translation
GO:1900015--regulation of cytokine production involved in inflammatory response
GO:1900744--regulation of p38MAPK cascade