CGDB Gene Information

Tag Content
CGDB ID CGD-MuM-021427
Uniprot Accession P56393; P56393; COX7B_MOUSE
Protein Name Cytochrome c oxidase subunit 7B, mitochondrial; Cytochrome c oxidase polypeptide VIIb
Gene Name Cox7b
Ensembl Information ENSMUST00000033582; ENSMUSP000000335
Genbank Protein ID NP_079655.1
Genbank Nucleotide ID NM_025379.2
Organism Mus musculus (Mouse)
NCBI Taxa ID 10090
Circadian Information
Evidence Phase Amplitude
(FOLD)		 Sentence Tissue/Cell Data type PMID
Peak Trough External
condition
Small-scale ZT 14 ZT 6 LD 2.00 Chronic circadian desynchronization disrupts mitochondrial oxidative metabolism genes (Ndufa1, Sdha, Cyc1, Atp5g2, Cox7b, Ndufv1, Uqcrc1 and Uqcrq) in the heart. heart Small-scale [1]
DescriptionThis protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Plays a role in proper central nervous system (CNS) development in vertebrates (By similarity).(View all)
PTM Sites
Count: 2
PositionPeptideTypePMID
75 PVGRVTPKEWRDQ ubiquitination 22790023
32 SHQKRAPSFHDKYGN phosphorylation 29574602; 22135298
Protein Sequence
(Fasta)		 MLPLAKNALS RLQVRSIQQV VARQSHQKRA PSFHDKYGNA ILAGGAIFCV STWTYTATQI 60
GIEWNMSPVG RVTPKEWRDQ
Sequence Source Uniprot/ENA
Orthology
CGDB IDSpieces IdentityE-ValueScore
CGD-AiM-053901Ailuropoda melanoleuca76.25 8.90e-34 139
CGD-AnP-048322Anas platyrhynchos57.81 3.50e-19 90.51
CGD-AnC-034256Anolis carolinensis73.91 7.70e-06 46.21
CGD-AsM-062716Astyanax mexicanus46.84 1.20e-14 75.48
CGD-BoT-037802Bos taurus81.25 2.30e-34 141
CGD-CaJ-029246Callithrix jacchus82.5 9.20e-36 145.6
CGD-CaF-062619Canis familiaris76.25 6.60e-34 139.4
CGD-CaP-029627Cavia porcellus82.5 5.40e-36 146.4
CGD-ChS-037656Chlorocebus sabaeus68.75 1.70e-29 124.8
CGD-ChH-029959Choloepus hoffmanni80.49 3.10e-15 77.41
CGD-DaR-038464Danio rerio48.1 1.80e-15 78.18
CGD-DaN-028711Dasypus novemcinctus76.25 3.60e-32 133.7
CGD-DiO-034518Dipodomys ordii58.18 3.30e-12 67.4
CGD-EcT-047267Echinops telfairi80 7.10e-36 146
CGD-EqC-030533Equus caballus67.5 2.20e-29 124.4
CGD-FeC-064637Felis catus78.75 7.80e-35 142.5
CGD-FiA-058126Ficedula albicollis53.16 3.50e-19 90.51
CGD-GaG-058508Gallus gallus50 1.80e-18 88.2
CGD-GoG-053735Gorilla gorilla80 2.10e-35 144.4
CGD-HoS-031981Homo sapiens (Human)78.75 7.80e-35 142.5
CGD-LaC-043570Latimeria chalumnae57.5 9.00e-23 102.4
CGD-LeO-040167Lepisosteus oculatus55 2.60e-22 100.9
CGD-LoA-038350Loxodonta africana82.5 1.60e-35 144.8
CGD-MaM-070413Macaca mulatta82.5 1.40e-36 148.3
CGD-MaE-037558Macropus eugenii68.18 1.40e-23 105.1
CGD-MeT-035639Medicago truncatula35.14 1.70e+00 28.49
CGD-MiM-061905Microcebus murinus77.5 2.10e-32 134.4
CGD-MoD-062974Monodelphis domestica66.18 1.40e-23 105.1
CGD-MuP-034496Mustela putorius furo62.5 7.10e-28 119.4
CGD-MyL-041611Myotis lucifugus86.08 4.10e-36 146.7
CGD-NoL-044840Nomascus leucogenys78.75 1.70e-34 141.4
CGD-OrA-049832Ornithorhynchus anatinus72.5 2.60e-30 127.5
CGD-OrC-051414Oryctolagus cuniculus80 7.10e-36 146
CGD-OrL-065602Oryzias latipes57.45 1.70e-13 71.63
CGD-OtG-028990Otolemur garnettii78.75 1.50e-33 138.3
CGD-OvA-030561Ovis aries75 5.40e-31 129.8
CGD-PaT-041084Pan troglodytes80 2.10e-35 144.4
CGD-PaA-066427Papio anubis82.5 1.40e-36 148.3
CGD-PeS-045109Pelodiscus sinensis68.75 3.20e-28 120.6
CGD-PoA-071115Pongo abelii80 2.10e-35 144.4
CGD-PrC-052178Procavia capensis80.49 5.40e-15 76.64
CGD-PtV-038306Pteropus vampyrus83.75 2.40e-36 147.5
CGD-RaN-060681Rattus norvegicus90 1.40e-39 158.3
CGD-SaH-033668Sarcophilus harrisii60 1.10e-15 78.95
CGD-SoA-046397Sorex araneus76.36 1.50e-20 95.13
CGD-SuS-058064Sus scrofa81.25 2.10e-35 144.4
CGD-TaG-051508Taeniopygia guttata51.9 4.60e-19 90.12
CGD-TaS-041241Tarsius syrichta65.38 8.70e-26 112.5
CGD-TeN-058922Tetraodon nigroviridis51.52 6.90e-15 76.26
CGD-TuB-055708Tupaia belangeri67.5 2.70e-27 117.5
CGD-TuT-071352Tursiops truncatus82.5 2.70e-35 144.1
CGD-ViP-054919Vicugna pacos82.5 2.10e-35 144.4
CGD-XeT-048339Xenopus tropicalis58.75 2.10e-24 107.8
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005746--C:mitochondrial respiratory chain
GO:0005739--C:mitochondrion
GO:0004129--F:cytochrome-c oxidase activity
GO:0007417--P:central nervous system development
Interpro

IPR008433--Cyt_c_oxidase_suVIIB
IPR023272--Cyt_c_oxidase_suVIIB_dom
Pfam

PF05392--COX7B