CGDB Gene Information


Tag Content
CGDB ID CGD-MuM-011351
Uniprot Accession A6H669; A6H669; A6H669_MOUSE
Protein Name Bardet-Biedl syndrome 4 (Human)
Gene Name Bbs4; mCG_22638
Genbank Protein ID NP_780534.1
Genbank Nucleotide ID NM_175325.3
Organism Mus musculus (Mouse)
NCBI Taxa ID 10090
Circadian Information
Evidence Phase Amplitude
(FOLD)
Sentence Tissue/Cell Data type PMID
Peak Trough External
condition
High-throughput ZT 22 ZT 10 LD 2.58 This study provides an important chronobiological resource (www.wgpembroke.com/shiny/SCNseq/) and allows us to propose that transcriptional timing in the SCN is gating clock resetting mechanisms. SCN RNA-seq [1]
Protein Sequence
(Fasta)
MAEVKLGMKT QVPASVESQK PRSKKAPDFP IVEKQNWLIH LHYIRKDYEA CKAVIKEQLQ 60
ETQGLCEYAI YVQALIFRLE GNIQESLELF QTCAVLSPQC ADNLKQVARS LFLLGKHKAA 120
TEVYNEAAKL NQKDWEICHN LGVCYTYLKQ FNKAQDQLHS ALQLNKHDLT YIMLGKIHLL 180
QGDLDKAIEI YKKAVEFSPE NTELLTTLGL LYLQLGVYQK AFEHLGNALT YDPANYKAIL 240
AAGSMMQTHG DFDVALTKYR VVACAIPESP PLWNNIGMCF FGKKKYVAAI SCLKRANYLA 300
PFDWKILYNL GLVHLTMQQY ASAFHFLSAA INFQPKMGEL YMLLAVALTN LEDIENARRA 360
YVEAVRLDKC NPLVNLNYAV LLYNQGEKKS ALAQYQEMEK KVNFLKDNSP LEFDSEMVEM 420
AQKLGAALQV GEALVWTKPV KDPKTKHRTN SGSKSATLQQ PLGSIQALGQ AMSSAAAYRK 480
ILSGAVGAQL PKPPSLPLEP EPEPTVEASP TEASEQKKEK
Sequence Source Uniprot/ENA
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Gene Ontology

GO:0034464--C:BBSome
GO:0034451--C:centriolar satellite
GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0060170--C:ciliary membrane
GO:0035869--C:ciliary transition zone
GO:0031514--C:motile cilium
GO:0005634--C:nucleus
GO:0000242--C:pericentriolar material
GO:0003777--F:microtubule motor activity
GO:0051297--P:centrosome organization
GO:0051457--P:maintenance of protein location in nucleus
GO:0034454--P:microtubule anchoring at centrosome
GO:0000281--P:mitotic cytokinesis
GO:0035058--P:nonmotile primary cilium assembly
GO:0071539--P:protein localization to centrosome
GO:0061512--P:protein localization to cilium
GO:0032465--P:regulation of cytokinesis

Interpro

IPR028786--BBS4
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat

PROSITE

PS50005--TPR
PS50293--TPR_REGION

Pfam

PF13414--TPR_11
PF13181--TPR_8