| Tag |
Content |
| CGDB ID |
CGD-MuM-014865 |
| Uniprot Accession |
Q564D0; Q564D0; Q564D0_MOUSE
|
| Protein Name |
Fusion, derived from t(12;16) malignant liposarcoma (Human), isoform CRA_a |
| Gene Name |
Fus; mCG_133502 |
| Genbank Protein ID |
NP_631888.1 |
| Genbank Nucleotide ID |
NM_139149.2 |
| Organism |
Mus musculus (Mouse) |
| NCBI Taxa ID |
10090 |
Circadian Information
|
| Evidence |
Phase |
Amplitude
(FOLD) |
Sentence |
Tissue/Cell |
Data type |
PMID |
| Peak |
Trough |
External
condition |
| High-throughput |
CT 6 |
CT 17 |
DD2 |
5.07 |
Identified over 3,000 different transcripts in the mouse liver that cycle with a period length of approximately 24 hours. |
liver |
Microarray |
[1] |
| High-throughput |
CT 6 |
CT 18 |
DD1 |
1.10 |
The circadian clock modulates renal function and identifies the 20-HETE synthesis pathway as one of its principal renal targets. |
kidney |
Microarray |
[1] |
| High-throughput |
ZT 7 |
ZT 19 |
LD |
1.77 |
Peripheral circadian desynchrony marks an early event in the metabolic disruption associated with chronic shiftwork. |
liver |
Microarray |
[1] |
| High-throughput |
ZT 10 |
ZT 18 |
LD |
1.22 |
Mice are most sensitive to UVB-induced DNA damage in the epidermis at night. |
anagen epidermis |
Microarray |
[1] |
| High-throughput |
ZT 8 |
ZT 20 |
LD |
2.17 |
It is specifically the nutritional challenge, and not the development of obesity, that causes the reprogramming of the clock and the effects of diet on the clock are reversible. |
liver |
Microarray |
[1] |
| High-throughput |
CT 15 |
CT 3 |
DD2 |
1.51 |
Sleep or learning and memory disturbances observed in patients with intellectual disability are probably not related to the circadian clock in the hippocampus. |
hippocampus |
Microarray |
[1] |
|
Protein Sequence
(Fasta) |
MASNDYTQQA TQSYGAYPTQ PGQGYSQQSS QPYGQQSYSG YGQSADTSGY GQSSYGSSYG 60
QTQNTGYGTQ SAPQGYGSTG GYGSSQSSQS SYGQQSSYPG YGQQPAPSST SGSYGGSSQS 120
SSYGQPQSGG YGQQSGYGGQ QQSYGQQQSS YNPPQGYGQQ NQYNSSSGGG GGGGGGNYGQ 180
DQSSMSGGGG GGGYGNQDQS GGGGGGYGGG QQDRGGRGRG GGGGYNRSSG GYEPRGRGGG 240
RGGRGGMGGS DRGGFNKFGG PRDQGSRHDS EQDNSDNNTI FVQGLGENVT IESVADYFKQ 300
IGIIKTNKKT GQPMINLYTD RETGKLKGEA TVSFDDPPSA KAAIDWFDGK EFSGNPIKVS 360
FATRRADFNR GGGNGRGGRG RGGPMGRGGY GGGGSGGGGR GGFPSGGGGG GGQQRAGDWK 420
CPNPTCENMN FSWRNECNQC KAPKPDGPGG GPGGSHMGGN YGDDRRGRGG YDRGGYRGRG 480
GDRGGFRGGR GGGDRGGFGP GKMDSRGEHR QDRRERPY 518Fasta Sequence
>CGD-MuM-014865|Q564D0|Fusion, derived from t(12;16) malignant liposarcoma (Human), isoform CRA_a|Mus musculus (Mouse)
MASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYGQSADTSGYGQSSYGSSYGQTQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQSYGQQQSSYNPPQGYGQQNQYNSSSGGGGGGGGGNYGQDQSSMSGGGGGGGYGNQDQSGGGGGGYGGGQQDRGGRGRGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHRQDRRERPY |
| Sequence Source |
Uniprot/ENA |
| Keyword |
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
|
| Gene Ontology |
GO:0044327--C:dendritic spine head
GO:0005654--C:nucleoplasm
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0005844--C:polysome
GO:0000166--F:nucleotide binding
GO:0044822--F:poly(A) RNA binding
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0071277--P:cellular response to calcium ion
|
| Interpro |
IPR012677--Nucleotide-bd_a/b_plait
IPR000504--RRM_dom
IPR001876--Znf_RanBP2
|
| PROSITE |
PS50102--RRM
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
|
| Pfam |
PF00076--RRM_1
PF00641--zf-RanBP
|
