| Tag |
Content |
| CGDB ID |
CGD-MuM-013924 |
| Uniprot Accession |
Q3TDI2; Q3TDI2; Q3TDI2_MOUSE
|
| Protein Name |
Wolfram syndrome 1 homolog (Human) |
| Gene Name |
Wfs1; mCG_20615 |
| Genbank Protein ID |
NP_035846.1 |
| Genbank Nucleotide ID |
NM_011716.2 |
| Organism |
Mus musculus (Mouse) |
| NCBI Taxa ID |
10090 |
Circadian Information
|
| Evidence |
Phase |
Amplitude
(FOLD) |
Sentence |
Tissue/Cell |
Data type |
PMID |
| Peak |
Trough |
External
condition |
| High-throughput |
ZT 22 |
ZT 14 |
LD |
1.21 |
Mice are most sensitive to UVB-induced DNA damage in the epidermis at night. |
anagen epidermis |
Microarray |
[1] |
|
Protein Sequence
(Fasta) |
MNSGTPPPSP SGPPPPPAPQ PQARARLNAT ASLEQDKIEP PRAPRPQADP SAGRSAGEAA 60
APEPRAPQTG SREETDRAGP MKADVEIPFE EVLEKAKAGD PKAQTEVGKH YLRLANDADE 120
ELNSCSAVAW LILAAKQGRR EAVKLLRRCL ADRKGITSEN EAEVKQLSSE TDLERAVRKA 180
ALVMYWKLNP KKKKQVAVSE LLENVGQVNE QDGGAQPGPV PKSLQKQRRM LERLVSSESK 240
NYIALDDFVE LTKKYAKGII PTNLFLQDED EDEDELAGKS PEDLPLRQKV VKYPLHAIME 300
IKEYLIDVAS KAGMHWLSTI VPTHHINALI FFFIISNLTI DFFAFFIPLV VFYLSFVSMV 360
ICTLKVFQDS KAWENFRTLT DLLLRFEPNL DVEQAEVNFG WNHLEPYIHF LLSVVFVIFS 420
FPLASKDCIP CSELAVISTF FTVTSYMSLS SSAEPYTRRA LVTEVAAGLL SLLPTVPVDW 480
RFLKVLGQTF FTVPVGHFII LNVSLPCLLY VYLFYLFFRM AQLRNFKGTY CYLVPYLVCF 540
MWCELSVVIL LQSTGLGLVR ASIGYFLFLF ALPILVAGLA LMGTVQFARW FLSLDLTKIM 600
VTTVICGVPL LFRWWTKANF SVMGMVKSLT KSSMVKLILV WLTAILLFCW FYVYRSEGMK 660
VYNSTLTWQQ YGFLCGPRAW KETNMARTQI LCSHLEGHRV TWTGRFKYVR VTEIDNSAES 720
AINMLPFFLG DWMRCLYGEA YPSCSSGNTS TAEEELCRLK QLAKHPCHIK KFDRYKFEIT 780
VGMPFGTNGN RGHEEDDITK DIVLRASSEF KDVLLNLRQG SLIEFSTILE GRLGSKWPVF 840
ELKAISCLNC MTQLSPARRH VKIEQDWRST VHGALKFAFD FFFFPFLSAA Fasta Sequence
>CGD-MuM-013924|Q3TDI2|Wolfram syndrome 1 homolog (Human)|Mus musculus (Mouse)
MNSGTPPPSPSGPPPPPAPQPQARARLNATASLEQDKIEPPRAPRPQADPSAGRSAGEAAAPEPRAPQTGSREETDRAGPMKADVEIPFEEVLEKAKAGDPKAQTEVGKHYLRLANDADEELNSCSAVAWLILAAKQGRREAVKLLRRCLADRKGITSENEAEVKQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVSELLENVGQVNEQDGGAQPGPVPKSLQKQRRMLERLVSSESKNYIALDDFVELTKKYAKGIIPTNLFLQDEDEDEDELAGKSPEDLPLRQKVVKYPLHAIMEIKEYLIDVASKAGMHWLSTIVPTHHINALIFFFIISNLTIDFFAFFIPLVVFYLSFVSMVICTLKVFQDSKAWENFRTLTDLLLRFEPNLDVEQAEVNFGWNHLEPYIHFLLSVVFVIFSFPLASKDCIPCSELAVISTFFTVTSYMSLSSSAEPYTRRALVTEVAAGLLSLLPTVPVDWRFLKVLGQTFFTVPVGHFIILNVSLPCLLYVYLFYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLQSTGLGLVRASIGYFLFLFALPILVAGLALMGTVQFARWFLSLDLTKIMVTTVICGVPLLFRWWTKANFSVMGMVKSLTKSSMVKLILVWLTAILLFCWFYVYRSEGMKVYNSTLTWQQYGFLCGPRAWKETNMARTQILCSHLEGHRVTWTGRFKYVRVTEIDNSAESAINMLPFFLGDWMRCLYGEAYPSCSSGNTSTAEEELCRLKQLAKHPCHIKKFDRYKFEITVGMPFGTNGNRGHEEDDITKDIVLRASSEFKDVLLNLRQGSLIEFSTILEGRLGSKWPVFELKAISCLNCMTQLSPARRHVKIEQDWRSTVHGALKFAFDFFFFPFLSAA |
| Sequence Source |
Uniprot/ENA |
| Keyword |
KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
|
| Gene Ontology |
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0000502--C:proteasome complex
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0030433--P:ER-associated ubiquitin-dependent protein catabolic process
GO:0042593--P:glucose homeostasis
GO:0001822--P:kidney development
GO:1903892--P:negative regulation of ATF6-mediated unfolded protein response
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:2000675--P:negative regulation of type B pancreatic cell apoptotic process
GO:0051928--P:positive regulation of calcium ion transport
GO:0031398--P:positive regulation of protein ubiquitination
GO:0050821--P:protein stabilization
GO:0003091--P:renal water homeostasis
GO:0007605--P:sensory perception of sound
GO:0007601--P:visual perception
|
| Interpro |
IPR026208--Wolframin
IPR026209--Wolframin_fam
|
