| Tag |
Content |
| CGDB ID |
CGD-MuM-011148 |
| Uniprot Accession |
A2AEG2; A2AEG2; A2AEG2_MOUSE
|
| Protein Name |
Oral-facial-digital syndrome 1 gene homolog (Human) |
| Gene Name |
Ofd1; mCG_116029 |
| Genbank Protein ID |
NP_803178.2 |
| Genbank Nucleotide ID |
NM_177429.3 |
| Organism |
Mus musculus (Mouse) |
| NCBI Taxa ID |
10090 |
Circadian Information
|
| Evidence |
Phase |
Amplitude
(FOLD) |
Sentence |
Tissue/Cell |
Data type |
PMID |
| Peak |
Trough |
External
condition |
| High-throughput |
ZT 8 |
ZT 20 |
LD |
1.40 |
It is specifically the nutritional challenge, and not the development of obesity, that causes the reprogramming of the clock and the effects of diet on the clock are reversible. |
liver |
Microarray |
[1] |
| High-throughput |
ZT 4 |
ZT 16 |
LD |
2.88 |
This study provides an important chronobiological resource (www.wgpembroke.com/shiny/SCNseq/) and allows us to propose that transcriptional timing in the SCN is gating clock resetting mechanisms. |
SCN |
RNA-seq |
[1] |
|
Protein Sequence
(Fasta) |
MRMAQSNMPH KSDVLSQDEL RKKLYQTFKD RGVLDTLQTQ LRNQLIHELM HPVLSGEVKP 60
PSISVEGSAL LIGASNSLVA DHLQRCGYEY SLSVFFPESG LAKEKIFTMQ DLLQLIRINP 120
SSSLYKSLIS GFDKENKKGF LMSFLKELAE YYQAKESCDA ETQTSTTFPS QVSLAEKFQL 180
IDAQFADGFP HRSKLESLET KLNEYKKEVQ HQLQVEMCHK LKYFREAEIT KVKMEERRKY 240
EKELAEFQNE FERTCQAKNE ALISQEKNSL ERIKKHREME SKEIYAQRQL LLNDIALLRG 300
REAELKERIE TFELTQKLQE EKIKSEAEAL ERREQNLKNI EDTYDQKLKT ELLKYQLELK 360
DDYITRTNKL LEEERKNKEK TIHLQEELTV INSKKEELSK SVKHMKEVEL ELESVKAQFL 420
AISKQNHLLN EKVREMSDYS QLKEEKVELQ AQNKLLKLQL EETRNENLRL LDRITQPPPE 480
LVIFQKELQK TEKAMELEHK DFETHRQALE KQLQSEIENS AQLRTQIAEY DASVKRLTVQ 540
VAELKSQLKQ TQIALENEVY RNPKHSLIHS LSGLLLSGKM APHSEDKSGD FLNVPLEQNK 600
VIAGAVMSRV PPYVNTATEA SSPESDFEFI ASSTKAKVRE LEQEAERLEK AFRTYYQRAT 660
QNPSTSPQPA KSPPSVNSVA ALRSIASSSM DRPVSAEDRV VSEQPLGDML KEEMSDMSKA 720
FMGSVVSRPR RTSSSTRLSS TPHPKSRRSL DNEMYLEGLG RLHMTSSSPL LDRVSASPAA 780
SPSPCPERTA QASPVPSRHS FSGLPEQNAC LYQRQTETQD KSELSNVDKQ SLKDEKFEPP 840
FRWNKTEQFE AEGLHPAGDM PGIDFAVATQ SSRLISYDYP SAVQSQTGEQ DEQELWELHM 900
KERRQREEQR HNERQEALER ERRELGKLEQ ERRMIEESLK MEMEEELEKS VQDQKDKSAH 960
CENTLEKYMK IIQQRQEESN ADKSSKKSGK ECSLVDMMMP SDKDESSPGF SHEEPDDMW 1019Fasta Sequence
>CGD-MuM-011148|A2AEG2|Oral-facial-digital syndrome 1 gene homolog (Human)|Mus musculus (Mouse)
MRMAQSNMPHKSDVLSQDELRKKLYQTFKDRGVLDTLQTQLRNQLIHELMHPVLSGEVKPPSISVEGSALLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPSSSLYKSLISGFDKENKKGFLMSFLKELAEYYQAKESCDAETQTSTTFPSQVSLAEKFQLIDAQFADGFPHRSKLESLETKLNEYKKEVQHQLQVEMCHKLKYFREAEITKVKMEERRKYEKELAEFQNEFERTCQAKNEALISQEKNSLERIKKHREMESKEIYAQRQLLLNDIALLRGREAELKERIETFELTQKLQEEKIKSEAEALERREQNLKNIEDTYDQKLKTELLKYQLELKDDYITRTNKLLEEERKNKEKTIHLQEELTVINSKKEELSKSVKHMKEVELELESVKAQFLAISKQNHLLNEKVREMSDYSQLKEEKVELQAQNKLLKLQLEETRNENLRLLDRITQPPPELVIFQKELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQIAEYDASVKRLTVQVAELKSQLKQTQIALENEVYRNPKHSLIHSLSGLLLSGKMAPHSEDKSGDFLNVPLEQNKVIAGAVMSRVPPYVNTATEASSPESDFEFIASSTKAKVRELEQEAERLEKAFRTYYQRATQNPSTSPQPAKSPPSVNSVAALRSIASSSMDRPVSAEDRVVSEQPLGDMLKEEMSDMSKAFMGSVVSRPRRTSSSTRLSSTPHPKSRRSLDNEMYLEGLGRLHMTSSSPLLDRVSASPAASPSPCPERTAQASPVPSRHSFSGLPEQNACLYQRQTETQDKSELSNVDKQSLKDEKFEPPFRWNKTEQFEAEGLHPAGDMPGIDFAVATQSSRLISYDYPSAVQSQTGEQDEQELWELHMKERRQREEQRHNERQEALERERRELGKLEQERRMIEESLKMEMEEELEKSVQDQKDKSAHCENTLEKYMKIIQQRQEESNADKSSKKSGKECSLVDMMMPSDKDESSPGFSHEEPDDMW |
| Sequence Source |
Uniprot/ENA |
| Keyword |
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
|
| Gene Ontology |
GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0016020--C:membrane
|
| Interpro |
IPR006594--LisH
|
| PROSITE |
PS50896--LISH
|
| Pfam |
PF16045--LisH_2
|
